Gene Information

Name : Mrub_1333 (Mrub_1333)
Accession : YP_003507115.1
Strain : Meiothermus ruber DSM 1279
Genome accession: NC_013946
Putative virulence/resistance : Unknown
Product : 5-carboxymethyl-2-hydroxymuconate semialdehyde dehydrogenase
Function : -
COG functional category : C : Energy production and conversion
COG ID : COG1012
EC number : 1.2.1.8
Position : 1366857 - 1368374 bp
Length : 1518 bp
Strand : -
Note : TIGRFAM: 5-carboxymethyl-2-hydroxymuconate semialdehyde dehydrogenase; PRIAM: Betaine-aldehyde dehydrogenase; PFAM: Aldehyde Dehydrogenase; InterPro IPR015590:IPR016160:IPR011985; KEGG: rpb:RPB_1706 5-carboxymethyl-2-hydroxymuconate semialdehyde dehydroge

DNA sequence :
ATGAAGGTATCGGAGAAAACCCAGGCCATCCGCCCTGAGTTCATCGCGCAGGTGCGGAACAAAATTGCCACCCACACCGT
AACGCACTTCATCAACGGGGCCTTTGTGCCGGGGGTGCGGGGCGAGCTGTTCGAGAGCCTCGACCCCTCCAACAACCAGG
TGCTGGCCTACGCCTACAGGGGCCACGCCGAGGACGTGGACAAAGCCGCCAAAGCCGCCAAGGCAGCGTTTCCCCGGTGG
AAACAGAGCGCCAAAACCCGCAAGAGATACCTGCTCAAGATTGCCGAGGTGCTGGAGAAGCACGGCGACGAGCTAGCGGT
GATGGAGTGCCTGGACGCCGGGCAGGCCCTGCGGATCGTGCGGGCCCAGGTGGCGCGGGCCGCCGAGAACTTTAGCTTTT
ACGCCGAGTACGCCGAGCGGGCCATGGACGGGCGCAGCTACCCGGTGGACAGCGAGTGGCTCAACTACAGCATTCGCGTA
CCGGTCGGGGTCTGCGGCATCATCACCCCCTGGAACGCCCCCATGATGCTCTCCACCTGGCGCATTGCCCCGGCCCTGGC
TTTCGGCAACACGGTGGTCTTGAAACCCGCCGAGTGGTCGCCCCTGACCGCCTGGAAGCTGGCGGAGATCATGCAGGAAG
CCGACCTGCCGCCGGGGGTCTTCAATGTGGTGCAGGGCTTCGGCGAGGAGGCCGGCGACGCGGTGGTGCGCCATCCGGAC
ATCCCCCTAATCGCCTTCACCGGGGAGACCACCACCGGCAGCCTCATCACCCGCAACAGCGCGGAGCACCTCAAGCGGCT
CTCCCTCGAGCTCGGCGGGAAATCCCCCGCCATCATCTTCGAGGACGCCGACCTCGAGCGGGCCCTGGATGCTACCATCT
TCCAGATTTATAGCTTCAACGGCGAGCGCTGCACCGCCAACTCACGGGCGCTGGTGCAGGAAAGCATCTTTGAAGAGTTC
GTGCAACGGGTGGCCGAACGGGCTGCCCGGATCAAGGTGGGGCATCCCCTCGAGCCCGACACCGAGGTGGGCCCCCTGAT
CCACCCCGAGCACCTGCAGCGCGTGCTGGGCTACGTGGAAATTGGCAAACAGGAGTCCCAGCACATCTTCGGCGGTGAGC
GGGTGGGCACCGAGGGCAACTATGTGCGGCCCGGCCTGTTTGTGGCCGAAAACCACCACCGCATCGCCCAGGAGGAGATT
TTTGGCCCCATCCTGACCGTCATCCCCTTCAAGGACGAGGCCGACGCCCTGCAAAAGGCCAACGACTCCAAGTACGGCCT
GGCCTCCTACGTCTGGACGCGGGACGTAGCCCGGGCGCACCGCATGGCCCTGCACCTGGAGGCCGGTATGACCTGGATCA
ACTCGCACAACGTGCGGCACCTGCCCACCCCCTTTGGCGGGGTCAAGATGAGCGGCACCCACCGCGAGGGCGGCGAGCAC
AGCCTGGAGTTCTACACCGAGCTGAAGCACATCGCCCTGCCGCTCACCGAGCACGCAATTCCGAAGTTTGGGAAGTGA

Protein sequence :
MKVSEKTQAIRPEFIAQVRNKIATHTVTHFINGAFVPGVRGELFESLDPSNNQVLAYAYRGHAEDVDKAAKAAKAAFPRW
KQSAKTRKRYLLKIAEVLEKHGDELAVMECLDAGQALRIVRAQVARAAENFSFYAEYAERAMDGRSYPVDSEWLNYSIRV
PVGVCGIITPWNAPMMLSTWRIAPALAFGNTVVLKPAEWSPLTAWKLAEIMQEADLPPGVFNVVQGFGEEAGDAVVRHPD
IPLIAFTGETTTGSLITRNSAEHLKRLSLELGGKSPAIIFEDADLERALDATIFQIYSFNGERCTANSRALVQESIFEEF
VQRVAERAARIKVGHPLEPDTEVGPLIHPEHLQRVLGYVEIGKQESQHIFGGERVGTEGNYVRPGLFVAENHHRIAQEEI
FGPILTVIPFKDEADALQKANDSKYGLASYVWTRDVARAHRMALHLEAGMTWINSHNVRHLPTPFGGVKMSGTHREGGEH
SLEFYTELKHIALPLTEHAIPKFGK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
hpaE AAO17179.1 HpaE Not tested tcd island Protein 1e-106 49
ORF SG19 AAN62241.1 putative aldehyde dehydrogenase Not tested PAGI-3(SG) Protein 1e-72 42