Gene Information

Name : tir (G2583_4416)
Accession : YP_003501867.1
Strain : Escherichia coli CB9615
Genome accession: NC_013941
Putative virulence/resistance : Virulence
Product : translocated intimin receptor Tir
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 4487440 - 4489110 bp
Length : 1671 bp
Strand : -
Note : -

DNA sequence :
ATGCCTATTGGTAATCTTGGTCATAATCCCAATGTGAATAATTCAATTCCTCCTGCACCTCCATTACCTTCACAAACCGA
CGGTGCAGGGGGGCGTGGTCAGCTCATTAACTCTACGGGGCCGTTGGGATCTCGTGCGCTATTTACGCCTGTAAGGAATT
CTATGGCTGATTCTGGCGACAATCGTGCCAGTGATGTTCCTGGACTTCCTGTAAATCCGATGCGCCTGGCGGCGTCTGAG
ATAACACTGAATGATGGATTTGAAGTTCTTCATGATCATGGTCCGCTCGATACTCTTAACAGGCAGATTGGCTCTTCGGT
ATTTCGAGTTGAAACTCAGGAAGATGGTAAACATATTGCTGTCGGTCAGAGGAATGGTGTTGAGACCTCTGTTGTTTTAA
GTGATCAAGAGTACGCTCGCTTGCAGTCCATTGATCCTGAAGGTAAAGACAAATTTGTATTTACTGGAGGCCGTGGTGGT
GCTGGGCATGCTATGGTCACCGTTGCTTCAGATATCACGGAAGCCCGCCAAAGGATACTGGAGCTGTTAGAGCCCAAAGG
GACCGGGGAGTCCAAAGGTGCTGGGGAGTCAAAAGGCGTTGGGGAGTTGAGGGAGTCAAATAGCGGTGCGGAAAACACCA
CAGAAACTCAGACCTCAACCTCAACTTCCAGCCTTCGTTCAGATCCTAAACTTTGGTTGGCGTTGGGGACTGTTGCTACA
GGTCTGATAGGGTTGGCGGCGACGGGTATTGTACAGGCGCTTGCATTGACGCCGGAGCCGGATAGCCCAACCACGACCGA
CCCTGATGCAGCTGCAAGTGCAACTGAAACTGCGACAAGAGATCAGTTAACGAAAGAAGCGTTCCAGAACCCAGATAATC
AAAAAGTTAATATCGATGAGCTCGGAAATGCGATTCCGTCAGGGGTATTGAAAGATGATGTTGTTGCGAATATAGAAGAG
CAGGCTAAAGCAGCAGGCGAAGAGGCCAAACAGCAAGCCATTGAAAATAATGCTCAGGCGCAAAAAAAATATGATGAACA
ACAAGCTAAACGCCAGGAGGAGCTGAAAGTTTCATCGGGGGCTGGCTACGGTCTTAGTGGCGCATTGATTCTTGGTGGGG
GAATTGGTGTTGCCGTCACCGCTGCGCTTCATCGAAAAAATCAGCCGGTAGAACAAACAACAACAACAACTACTACAACT
ACAAGCGCACGTACGGTAGAGAATAAGCCTGCAAATAATACACCTGCACAGGGCAATGTAGATACCCCTGGGTCAGAAGA
TACCATGGAGAGCAGACGTAGCTCGATGGCTAGCACCTCGTCGACTTTCTTTGACACTTCCAGCATAGGGACCGTGCAGA
ATCCGTATGCTGATGTTAAAACATCGCTGCATGATTCGCAGGTGCCGACTTCTAATTCTAATACGTCTGTTCAGAATATG
GGGAATACAGATTCTGTTGTATATAGCACCATTCAACATCCTCCCCGGGATACTACTGATAACGGCGCACGGTTATTAGG
AAATCCAAGTGCGGGGATTCAAAGCACTTATGCGCGTCTGGCGCTAAGTGGTGGATTACGCCATGACATGGGAGGATTAA
CGGGGGGGAGTAATAGCGCTGTGAATACTTCGAATAACCCACCAGCGCCGGGATCCCATCGTTTCGTCTAA

Protein sequence :
MPIGNLGHNPNVNNSIPPAPPLPSQTDGAGGRGQLINSTGPLGSRALFTPVRNSMADSGDNRASDVPGLPVNPMRLAASE
ITLNDGFEVLHDHGPLDTLNRQIGSSVFRVETQEDGKHIAVGQRNGVETSVVLSDQEYARLQSIDPEGKDKFVFTGGRGG
AGHAMVTVASDITEARQRILELLEPKGTGESKGAGESKGVGELRESNSGAENTTETQTSTSTSSLRSDPKLWLALGTVAT
GLIGLAATGIVQALALTPEPDSPTTTDPDAAASATETATRDQLTKEAFQNPDNQKVNIDELGNAIPSGVLKDDVVANIEE
QAKAAGEEAKQQAIENNAQAQKKYDEQQAKRQEELKVSSGAGYGLSGALILGGGIGVAVTAALHRKNQPVEQTTTTTTTT
TSARTVENKPANNTPAQGNVDTPGSEDTMESRRSSMASTSSTFFDTSSIGTVQNPYADVKTSLHDSQVPTSNSNTSVQNM
GNTDSVVYSTIQHPPRDTTDNGARLLGNPSAGIQSTYARLALSGGLRHDMGGLTGGSNSAVNTSNNPPAPGSHRFV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ECs4561 NP_312588.1 hypothetical protein Virulence LEE Protein 0.0 99
tir AAC31506.1 L0027 Virulence LEE Protein 0.0 99
tir AAY25390.1 translocated intimin receptor Virulence LEE Protein 0.0 99
tir AAY25391.1 translocated intimin receptor Virulence LEE Protein 0.0 99
tir AAY25392.1 translocated intimin receptor Virulence LEE Protein 0.0 99
tir ACU09451.1 translocated intimin receptor protein Tir Virulence LEE Protein 0.0 99
tir NP_290261.1 translocated intimin receptor protein Not tested LEE Protein 0.0 99
espE CAC81869.1 EspE protein Virulence LEE II Protein 8e-116 67
tir YP_003232160.1 translocated intimin receptor Tir Virulence LEE Protein 1e-115 67
tir AAL57549.1 Tir Virulence LEE Protein 2e-115 66
tir YP_003223468.1 translocated intimin receptor Tir Virulence LEE Protein 2e-113 66
tir CAI43867.1 translocated intimin receptor Not tested LEE Protein 1e-113 66
tir AAK26722.1 Tir Virulence LEE Protein 2e-115 66
tir AAC38390.1 Tir Virulence LEE Protein 6e-86 60
tir YP_003236081.1 putative translocated intimin receptor Tir Not tested LEE Protein 4e-82 60
tir AAY25393.1 translocated intimin receptor Virulence LEE Protein 1e-81 60
tir AAY25395.1 translocated intimin receptor Virulence LEE Protein 1e-81 60
tir AAY25394.1 translocated intimin receptor Virulence LEE Protein 4e-82 60
unnamed AAL06376.1 translocated intimin receptor Tir Virulence LEE Protein 1e-79 59

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
tir YP_003501867.1 translocated intimin receptor Tir VFG0805 Protein 0.0 99
tir YP_003501867.1 translocated intimin receptor Tir VFG0737 Protein 3e-86 60