Gene Information

Name : eae (G2583_4414)
Accession : YP_003501865.1
Strain : Escherichia coli CB9615
Genome accession: NC_013941
Putative virulence/resistance : Virulence
Product : Gamma intimin
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 4483968 - 4486772 bp
Length : 2805 bp
Strand : -
Note : -

DNA sequence :
ATGATTACTCATGGTTGTTATACCCGGACCCGGCACAAGCATAAGCTAAAAAAAACATTGATTATGCTTAGTGCTGGTTT
AGGATTGTTTTTTTATGTTAATCAGAATTCATTTGCAAATGGTGAAAATTATTTTAAATTGGGTTCGGATTCAAAACTGT
TAACTCATGATAGCTATCAGAATCGCCTTTTTTATACGTTGAAAACTGGTGAAACTGTTGCCGATCTTTCTAAATCGCAA
GATATTAATTTATCGACGATTTGGTCGTTGAATAAGCATTTATACAGTTCTGAAAGCGAAATGATGAAGGCCGCGCCTGG
TCAGCAGATCATTTTGCCACTCAAAAAACTTCCCTTTGAATACAGTGCACTACCACTTTTAGGTTCGGCACCTCTTGTTG
CTGCAGGTGGTGTTGCTGGTCACACGAATAAACTGACTAAAATGTCCCCGGACGTGACCAAAAGCAACATGACCGATGAC
AAGGCATTAAATTATGCGGCACAACAGGCGGCGAGTCTCGGTAGCCAGCTTCAGTCGCGATCTCTGAACGGCGATTACGC
GAAAGATACCGCTCTTGGTATCGCTGGTAACCAGGCTTCGTCACAGTTGCAGGCCTGGTTACAACATTATGGAACGGCAG
AGGTTAATCTGCAGAGTGGTAATAACTTTGACGGTAGTTCACTGGACTTCTTATTACCGTTCTATGATTCCGAAAAAATG
CTGGCATTTGGTCAGGTCGGAGCGCGTTACATTGACTCCCGCTTTACGGCAAATTTAGGTGCGGGTCAGCGTTTTTTCCT
TCCTGCAAACATGTTGGGCTATAACGTCTTCATTGATCAGGATTTTTCTGGTGATAATACCCGTTTAGGTATTGGTGGCG
AATACTGGCGAGACTATTTCAAAAGTAGCGTTAACGGCTATTTCCGCATGAGCGGCTGGCATGAGTCATACAATAAGAAA
GACTATGATGAGCGCCCAGCAAATGGCTTCGATATCCGTTTTAATGGCTATCTACCGTCATATCCGGCATTAGGCGCCAA
GCTGATATATGAGCAGTATTATGGTGATAATGTTGCTTTGTTTAATTCTGATAAGCTGCAGTCGAATCCTGGTGCGGCGA
CCGTTGGTGTAAACTATACTCCGATTCCTCTGGTGACGATGGGGATCGATTACCGTCATGGTACGGGTAATGAAAATGAT
CTCCTTTACTCAATGCAGTTCCGTTATCAGTTTGATAAATCGTGGTCTCAGCAAATTGAACCACAGTATGTTAACGAGTT
AAGAACATTATCAGGCAGCCGTTACGATCTGGTTCAGCGTAATAACAATATTATTCTGGAGTACAAGAAGCAGGATATTC
TTTCTCTGAATATTCCGCATGATATTAATGGTACTGAACACAGTACGCAGAAGATTCAGTTGATCGTTAAGAGCAAATAC
GGTCTGGATCGTATCGTCTGGGATGATAGTGCATTACGCAGTCAGGGCGGTCAGATTCAGCATAGCGGAAGCCAAAGCGC
ACAAGACTACCAGGCTATTTTGCCTGCTTATGTGCAAGGTGGCAGCAATATTTATAAAGTGACGGCTCGCGCCTATGACC
GTAATGGCAATAGCTCTAACAATGTACAGCTTACTATTACCGTTCTGTCGAATGGTCAAGTTGTCGACCAGGTTGGGGTA
ACGGACTTTACGGCGGATAAGACTTCGGCTAAAGCGGATAACGCCGATACCATTACTTATACCGCGACGGTGAAAAAGAA
TGGGGTAGCTCAGGCTAATGTCCCTGTTTCATTTAATATTGTTTCAGGAACTGCAACTCTTGGGGCAAATAGTGCCAAAA
CGGATGCTAACGGTAAGGCAACCGTAACGTTGAAGTCGAGTACGCCAGGACAGGTCGTCGTGTCTGCTAAAACCGCGGAG
ATGACTTCAGCACTTAATGCCAGTGCGGTTATATTTTTTGATCAAACCAAGGCCAGCATTACTGAGATTAAGGCTGATAA
GACAACTGCAGTAGCAAATGGTAAGGATGCTATTAAATATACTGTAAAAGTTATGAAAAACGGTCAGCCAGTTAATAATC
AATCCGTTACATTCTCAACAAACTTTGGGATGTTCAACGGTAAGTCTCAAACGCAAGCAACCACGGGAAATGATGGTCGT
GCGACGATAACACTAACTTCCAGTTCCGCCGGTAAAGCGACTGTTAGTGCGACAGTCAGTGATGGGGCTGAGGTTAAAGC
GACTGAGGTCACTTTTTTTGATGAACTGAAAATTGACAACAAGGTTGATATTATTGGTAACAATGTCAGAGGCGAGTTGC
CTAATATTTGGCTGCAATATGGTCAGTTTAAACTGAAAGCAAGCGGTGGTGATGGTACATATTCATGGTATTCAGAAAAT
ACCAGTATCGCGACTGTCGATGCATCAGGGAAAGTCACTTTGAATGGTAAAGGCAGTGTCGTAATTAAAGCCACATCTGG
TGATAAGCAAACAGTAAGTTACACTATAAAAGCACCGTCGTATATGATAAAAGTGGATAAGCAAGCCTATTATGCTGATG
CTATGTCCATTTGCAAAAATTTATTACCATCCACACAGACGGTATTGTCAGATATTTATGACTCATGGGGGGCTGCAAAT
AAATATAGCCATTATAGTTCTATGAACTCAATAACTGCTTGGATTAAACAGACATCTAGTGAGCAGAGTTCTGGAGTATC
AAGCACTTATAACCTAATAACACAAAACCCTCTTCCTAGGGTTAATGTTAATACTCCAAATGTCTATGCGGTTTGTGTAG
AATAA

Protein sequence :
MITHGCYTRTRHKHKLKKTLIMLSAGLGLFFYVNQNSFANGENYFKLGSDSKLLTHDSYQNRLFYTLKTGETVADLSKSQ
DINLSTIWSLNKHLYSSESEMMKAAPGQQIILPLKKLPFEYSALPLLGSAPLVAAGGVAGHTNKLTKMSPDVTKSNMTDD
KALNYAAQQAASLGSQLQSRSLNGDYAKDTALGIAGNQASSQLQAWLQHYGTAEVNLQSGNNFDGSSLDFLLPFYDSEKM
LAFGQVGARYIDSRFTANLGAGQRFFLPANMLGYNVFIDQDFSGDNTRLGIGGEYWRDYFKSSVNGYFRMSGWHESYNKK
DYDERPANGFDIRFNGYLPSYPALGAKLIYEQYYGDNVALFNSDKLQSNPGAATVGVNYTPIPLVTMGIDYRHGTGNEND
LLYSMQFRYQFDKSWSQQIEPQYVNELRTLSGSRYDLVQRNNNIILEYKKQDILSLNIPHDINGTEHSTQKIQLIVKSKY
GLDRIVWDDSALRSQGGQIQHSGSQSAQDYQAILPAYVQGGSNIYKVTARAYDRNGNSSNNVQLTITVLSNGQVVDQVGV
TDFTADKTSAKADNADTITYTATVKKNGVAQANVPVSFNIVSGTATLGANSAKTDANGKATVTLKSSTPGQVVVSAKTAE
MTSALNASAVIFFDQTKASITEIKADKTTAVANGKDAIKYTVKVMKNGQPVNNQSVTFSTNFGMFNGKSQTQATTGNDGR
ATITLTSSSAGKATVSATVSDGAEVKATEVTFFDELKIDNKVDIIGNNVRGELPNIWLQYGQFKLKASGGDGTYSWYSEN
TSIATVDASGKVTLNGKGSVVIKATSGDKQTVSYTIKAPSYMIKVDKQAYYADAMSICKNLLPSTQTVLSDIYDSWGAAN
KYSHYSSMNSITAWIKQTSSEQSSGVSSTYNLITQNPLPRVNVNTPNVYAVCVE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
eaeA AAC31504.1 L0025 Virulence LEE Protein 0.0 99
unnamed ACU09449.1 gamma intimin Virulence LEE Protein 0.0 99
eae NP_290259.1 intimin adherence protein Virulence LEE Protein 0.0 99
ECs4559 NP_312586.1 gamma intimin Virulence LEE Protein 0.0 99
eae YP_003236079.1 theta intimin Not tested LEE Protein 0.0 90
eae CAC81871.1 Intimin Not tested LEE II Protein 0.0 83
eae YP_003232162.1 intimin Not tested LEE Protein 0.0 83
eae AAK26724.1 intimin Virulence LEE Protein 0.0 83
eae AAL57551.1 Eae Virulence LEE Protein 0.0 83
eae AAC38392.1 intimin Virulence LEE Protein 0.0 83
eae YP_003223466.1 intimin epsilon Not tested LEE Protein 0.0 82
eae CAI43865.1 intimin epsilon Virulence LEE Protein 0.0 82
unnamed AAL06378.1 intimin Virulence LEE Protein 0.0 78
eae AFO66392.1 intimin-like protein Virulence SESS LEE Protein 0.0 60
eae AFO66294.1 intimin-like protein Not tested SESS LEE Protein 0.0 59

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
eae YP_003501865.1 Gamma intimin VFG0803 Protein 0.0 99
eae YP_003501865.1 Gamma intimin VFG0739 Protein 0.0 83