Gene Information

Name : thcA (SCAB_79811)
Accession : YP_003493471.1
Strain : Streptomyces scabiei 87.22
Genome accession: NC_013929
Putative virulence/resistance : Virulence
Product : aldehyde dehydrogenase
Function : -
COG functional category : C : Energy production and conversion
COG ID : COG1012
EC number : -
Position : 8844834 - 8846357 bp
Length : 1524 bp
Strand : -
Note : -

DNA sequence :
ATGACCCGTTTCGCAGCGCCCGGTACGGACGGCGCGGTCGTCTCCTTCGAGGCGCGGTACGACCATTTCATCGGGGGCGA
GTACGTGCCGCCGGCGCGTGGGCAGTACTTCGAGAACCCGAGTCCGGTGAACGGGCTGCCGTTCACGGAGATCGCGCGCG
GTACGAGTGAGGACGTGGAGCGCGCGCTGGACGCGGCGCACGCGGCCGCGCCCGGCTGGGGGCGGTCGTCCGTGACGGAG
CGTTCGGACGTGCTGCGGAAGATCGCCGACCGGATGGAGGCGAACCTGGAGCTGCTGGCGGTCGCGGAGAGCTGGGAGAA
CGGAAAGCCGGTGCGGGAGACGCTGGCCGCCGACATTCCTCTCGCGATCGACCACTTCCGGTATTTCGCGGGGGCGATCC
GCGCGCAGGAGGGTTCGCTCGCGGAGCTGGACGACGACACGGTGGCGTACCACTTCCATGAGCCGCTGGGTGTGGTCGCT
CAGATCATCCCGTGGAACTTCCCGATCCTGATGGCGACCTGGAAGCTGGCTCCCGCGTTGGCGGCAGGCAACGCGGTCGT
ACTGAAGCCGGCCGAGCAGACCCCGGCCTCCATCCATGTCTGGCTGAGCGTGGTGGCGGATCTGCTGCCGCCGGGTGTGC
TGAACATCGTCAACGGGTTCGGGGTCGAGGCGGGCAAGCCGCTGGCGTCGAGTCCCCGGGTGGCGAAGGTGGCGTTCACG
GGCGAGACGACCACCGGGAGGCTGATCATGCAGTACGCCTCGGAGAACATCACGCCGGTGACGCTCGAACTCGGGGGCAA
GTCGCCGAACATCTTCTTCGACGACGTGTGGTCCGCGAACGACGACTTCCGGGACAAGGCCCTCGAAGGCTTCACGATGT
TCGCGCTCAACCAGGGCGAGGTGTGCACCTGTCCGTCGCGGGCGCTGGTGCAGCGCGGCAACTACGCGGAGTTCATGGAG
GCGGCGGTCGCCCGCACCGAGCAGATCGTGACGGGGCATCCGCTGGACACCGACACCATGATCGGCGCCCAGGCGTCCAA
CGACCAGTTGGAGAAGATCCTCTCCTATCTGGACATCGGCCGGCAGGAAGGCGCGAAGATCCTGACCGGTGGTGAACGTA
TCGAGCACGACGGCGAGTTGAAGGGCGGCTACTACGTCCAGCCGACGATCTTCGAGGGCCACAACCGTATGCGGATCTTC
CAGGAGGAGATCTTCGGCCCGGTCGTCTCCGTGACCCCGTTCGACGACTTCGACGACGCCATCAAGATCGCGAACGACAC
CTTGTACGGTCTGGGGGCGGGCGTCTGGACTCGGGACGCCAACACGGCCTACCGCGCGGGCCGTTCCATCCAGGCGGGCC
GTGTCTGGACCAACTGCTACCACGCGTACCCGGCCCACGCCGCGTTCGGTGGCTACAAGGGTTCGGGCATCGGCCGCGAG
ACCCACAAGATGATGCTGGACCACTACCAGCAGACGAAGAACCTCCTGGTGAGCTACTCGCCGAAGAAGCTGGGCTTCTT
CTAG

Protein sequence :
MTRFAAPGTDGAVVSFEARYDHFIGGEYVPPARGQYFENPSPVNGLPFTEIARGTSEDVERALDAAHAAAPGWGRSSVTE
RSDVLRKIADRMEANLELLAVAESWENGKPVRETLAADIPLAIDHFRYFAGAIRAQEGSLAELDDDTVAYHFHEPLGVVA
QIIPWNFPILMATWKLAPALAAGNAVVLKPAEQTPASIHVWLSVVADLLPPGVLNIVNGFGVEAGKPLASSPRVAKVAFT
GETTTGRLIMQYASENITPVTLELGGKSPNIFFDDVWSANDDFRDKALEGFTMFALNQGEVCTCPSRALVQRGNYAEFME
AAVARTEQIVTGHPLDTDTMIGAQASNDQLEKILSYLDIGRQEGAKILTGGERIEHDGELKGGYYVQPTIFEGHNRMRIF
QEEIFGPVVSVTPFDDFDDAIKIANDTLYGLGAGVWTRDANTAYRAGRSIQAGRVWTNCYHAYPAHAAFGGYKGSGIGRE
THKMMLDHYQQTKNLLVSYSPKKLGFF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
VC0819 NP_230467.2 aldehyde dehydrogenase Not tested VPI-1 Protein 2e-147 60
aldA AAK20776.1 aldehyde dehydrogenase Virulence VPI Protein 6e-153 59
aldA AAC12273.1 aldehyde dehydrogenase Virulence VPI Protein 6e-153 59
aldA AAK20747.1 aldehyde dehydrogenase Virulence VPI Protein 6e-153 59
aldA-1 YP_001216300.1 aldehyde dehydrogenase Not tested VPI-1 Protein 1e-152 59

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
thcA YP_003493471.1 aldehyde dehydrogenase VFG0082 Protein 8e-148 60