Gene Information

Name : pyk2 (SCAB_28241)
Accession : YP_003488482.1
Strain : Streptomyces scabiei 87.22
Genome accession: NC_013929
Putative virulence/resistance : Virulence
Product : pyruvate kinase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0469
EC number : -
Position : 3227703 - 3229133 bp
Length : 1431 bp
Strand : +
Note : cluster 0606 with SCAB68861

DNA sequence :
ATGCGCCGTTCGAAAATCGTCTGTACTCTCGGCCCCGCGGTCGACTCCCACGAGCAACTGGTCGCCCTCATCGAGGCCGG
CATGAACGTGGCCCGTTTCAATTTCAGCCACGGCAGTCACGCCGAGCACCAGGGCCGCTACGACCGGGTCCGGGCCGCCG
CCGCCGAGACCGGTGCGGCCATCGGTGTCCTCGCCGACCTCCAGGGCCCCAAGATCCGCCTGGAGACCTTCGCCGAGGGC
CCGGTGGAGCTGGTGCGCGGTGACGAGTTCACCATCACCGCCGAGGACGTGCCGGGCGACAGGCAGATCTGCGGCACGAC
GTACAAGGGCCTGCCCGGAGACGTCACCGCGGGCGACCAGATCCTCATCAACGACGGCAACGTCGAGCTGAAGGTCATCG
AGGTCGACGGCCCCCGGGTGCGGACCGAGGTCATCGAGGGCGGTGTCATCTCCGACCACAAGGGCATCAACCTGCCCGGC
GCGGCCGTCAACGTGCCCGCGCTGTCCGAGAAGGACGTCGAGGACCTGCGGTTCGCGCTGCGGATGGGCTGCGACCTGGT
GGCGCTGTCCTTCGTGCGGGACGCCGAGGACGTGCGGGACGTCCACAAGGTGATGGACGAGGTGGGCCGCCGGGTCCCCG
TCATCGCCAAGGTGGAGAAGCCGCAGGCGGTGGAGAACATGGAGGACGTCGTGATGGCGTTCGACGGCGTCATGGTCGCC
CGTGGCGACCTGGCCGTCGAGTACCCGCTCGAGAAGGTCCCCATGGTGCAGAAGCGGCTCATCGAGCTGTGCCGCCGCAA
CGCCAAGCCGGTGATCGTGGCGACCCAGATGATGGAGTCGATGATCACCAACTCCCGCCCCACGCGCGCCGAGGCGTCCG
ACGTCGCCAACGCGATCCTGGACGGCGCGGACGCGGTCATGCTGTCGGCGGAGTCCAGTGTGGGCGCGTACCCGCTGGAG
ACGGTCCGCACGATGTCGAAGATCGTGACGGCCGCCGAGCAGGAGCTGCTCTCCAAGGGCCTGCAGCCGCTGGTGCCGGG
CAAGAAGCCGCGTACGCAGGGCGGTTCGATCGCCCGTGCCGCCTGCGAGATCGCCGACTTCCTCGGCGGCCGGGCCCTGG
TGGCCTTCACGCAGTCCGGTGACACCGCCCGCCGGCTCTCGCGCTACCGCGCCTCCCAGCCGATCGTCGCGTTCACCACC
GACGAGTCCACCCGCAACCAGCTGGCGCTCAGCTGGGGTGTCGAGTCGCACGTCGTGCCGTTCGTGAACAGCACCGACGA
GATGGTCGACCTGGTGGACGGGGAGATGGTCAAGCTCAAGCGCTTCCAGGAGGGCGACATCGCGGTCATCACCGCCGGCT
CGCCCCCCGGTGTGCCGGGCACCACGAACATGGTCCGGGTGCACCACCTGGGCGGCGGCGCCCGCGACTGA

Protein sequence :
MRRSKIVCTLGPAVDSHEQLVALIEAGMNVARFNFSHGSHAEHQGRYDRVRAAAAETGAAIGVLADLQGPKIRLETFAEG
PVELVRGDEFTITAEDVPGDRQICGTTYKGLPGDVTAGDQILINDGNVELKVIEVDGPRVRTEVIEGGVISDHKGINLPG
AAVNVPALSEKDVEDLRFALRMGCDLVALSFVRDAEDVRDVHKVMDEVGRRVPVIAKVEKPQAVENMEDVVMAFDGVMVA
RGDLAVEYPLEKVPMVQKRLIELCRRNAKPVIVATQMMESMITNSRPTRAEASDVANAILDGADAVMLSAESSVGAYPLE
TVRTMSKIVTAAEQELLSKGLQPLVPGKKPRTQGGSIARAACEIADFLGGRALVAFTQSGDTARRLSRYRASQPIVAFTT
DESTRNQLALSWGVESHVVPFVNSTDEMVDLVDGEMVKLKRFQEGDIAVITAGSPPGVPGTTNMVRVHHLGGGARD

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
pykA NP_273151.1 pyruvate kinase Not tested IHT-A Protein 5e-64 43
STY1744 NP_456147.1 pyruvate kinase Not tested SPI-2 Protein 7e-76 42
pykF YP_216386.1 pyruvate kinase Not tested SPI-2 Protein 4e-76 42
pykF NP_805051.1 pyruvate kinase Not tested SPI-2 Protein 4e-76 42
pykF CAA68205.1 pyruvate kinase like protein Not tested SPI-2 Protein 2e-75 42

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
pyk2 YP_003488482.1 pyruvate kinase VFG0479 Protein 2e-76 42