Gene Information

Name : SCAB_1411 (SCAB_1411)
Accession : YP_003485938.1
Strain : Streptomyces scabiei 87.22
Genome accession: NC_013929
Putative virulence/resistance : Virulence
Product : AMP-binding NRPS ligase
Function : -
COG functional category : Q : Secondary metabolites biosynthesis, transport and catabolism
COG ID : COG1021
EC number : -
Position : 149399 - 150997 bp
Length : 1599 bp
Strand : -
Note : -

DNA sequence :
GTGAGACCGCCCGCCGAGATGATCCGGCGGTACCGGGAACGCGGGTACTGGACGGACGAGACACTCGGCGAGTGGCCGTA
CCGGACCCCCGACCACAGCGCCCGGATCGCCGTGGTCACCCCGGACCGCTCCCTGACCTTCGGCGCACTCGACCTGGCCG
CCGACCGTACGGCCGCGGGACTGCGGGCCCGCGGACTGCGGGCCGGCGAGCGCGTGGTCGTGCAACTGCCCAACTCGCCC
GAGCTGGTGGTGCTCTCGCTGGCGCTGTTCCGGCTGGGTGCTGTGCCGGTGTTCGCGCTCCCCGCCCACCGGGAGGCGGA
GATCACCCACCTGGTGGACACGGCCGAGGCCACCGTCTACGTCTGTCCGTCGGAGACCGTGGACGGTGACTACGCCCGGC
TCGCCAAGGAGGTCGCGGCCCGCTGCGGCACCCTGCGGGAGGTGCTGGTCGCGGGTGGCGGCGGTGCGTTCACGCCCCTC
GACGAGGTGGACGCGGAGCCTGTCGAACTGCCCGCGCCCGACCCGCTCGACGTGGCACTGTTCCTGCTCTCCGGCGGCAC
CACGGGCCGGCCCAAGCTGATCCCCCGTACCCACGCCGACTACACGTACCAGTTGCGGGAGAGCGCACGGCTGTGCGGCT
TCGGCCCGGACAGCCGCTACCTGGCGGCGCTGCCCATGGCGCACAACTTCGCGCTGGCCTGTCCGGGCGTGCTCGGCGTG
CTGCGGCTCGGCGGAACAGCCGTACTGGCACCGGTCCCGACACCGGACGTGTGCTTTCCGCTGGTCGAGCAGGCCCGGGC
CACGGCCTCCTCCCTGGTTCCGCCGCTGCTGCGCCTGTGGCTGGAGGCCGCGGAGTGGAACGACTGCGACCTCTCGTCCC
TGGGGCTGCTCCAGGTGGGCGGTGCGAAGCTGGACCCCGACACCGCGCGGCGGGTGCCCGCCACGCTCGGCTGCAGGCTG
CAGCAGGTCTACGGAATGGCCGAGGGCCTGCTCAACTTCACCCGCCTGGACGACCCTTCGGACGTCGTGTGCAACACCCA
GGGACGCCCGATGTCGCCGGCCGACGAGATCCTCGTGCTGCGCCGGGACGGCCGGCCCGCCGCCCCGGGCGAGCCGGGCG
AGCTGCTCACCCGCGGCCCCTACACCCTGCGCGGCTACTACCGGGCGTCCGACCACAACAGGACGAGTTTCACCGAGGAC
GGCTACTTCCGCACCGGTGACCTGGTGACCCGCACCACGGACGGGAACCTGGAAGTGGTGGGCCGGGTCAACGACGTGGT
CAACCGGGGCGGCGAGAAGGTGCCTGCGCTGGAGCTGGAGGAGCATCTGCTCGCCGACGACCGCATCAGGGCCGCCGCGG
TCATCGCGCTGCCCGACGAGCTGATGGGGGAGAGCACGTGCGCGTGCGTCGTGCCCCACGACCCGGGTGATCCGCCGACG
CTCCGCGAGGTACAGGCGGCCCTGAGGACGCGCGGGATCGCCGCCTACAAGCTGCCCGACCGCCTGGTGGTGCGGGCGAG
GCTGCCGCTGACGGGCGTGGGCAAGGTCGACAAGAAGGCGCTGCGCGCCCAGGTGCTCGACGAGGGACCGGTCGGCTGA

Protein sequence :
MRPPAEMIRRYRERGYWTDETLGEWPYRTPDHSARIAVVTPDRSLTFGALDLAADRTAAGLRARGLRAGERVVVQLPNSP
ELVVLSLALFRLGAVPVFALPAHREAEITHLVDTAEATVYVCPSETVDGDYARLAKEVAARCGTLREVLVAGGGGAFTPL
DEVDAEPVELPAPDPLDVALFLLSGGTTGRPKLIPRTHADYTYQLRESARLCGFGPDSRYLAALPMAHNFALACPGVLGV
LRLGGTAVLAPVPTPDVCFPLVEQARATASSLVPPLLRLWLEAAEWNDCDLSSLGLLQVGGAKLDPDTARRVPATLGCRL
QQVYGMAEGLLNFTRLDDPSDVVCNTQGRPMSPADEILVLRRDGRPAAPGEPGELLTRGPYTLRGYYRASDHNRTSFTED
GYFRTGDLVTRTTDGNLEVVGRVNDVVNRGGEKVPALELEEHLLADDRIRAAAVIALPDELMGESTCACVVPHDPGDPPT
LREVQAALRTRGIAAYKLPDRLVVRARLPLTGVGKVDKKALRAQVLDEGPVG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ybtE NP_993003.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 1e-93 49
ybtE YP_070120.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 1e-93 49
ybtE CAA21394.1 - Virulence HPI Protein 1e-93 49
ybtE YP_853079.1 yersiniabactin siderophore biosynthetic protein Virulence PAI IV APEC-O1 Protein 9e-94 49
irp5 CAA73130.1 Irp5 protein Virulence HPI Protein 1e-92 49
ybtE AAA93464.1 yersiniabactin 2,3-dihydoxybenzoate-AMP ligase Virulence HPI Protein 8e-94 49
irp5 YP_001006819.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 2e-92 49
irp5 YP_002346898.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 1e-93 49
ybtE NP_669710.1 salicyl-AMP ligase Virulence HPI Protein 1e-93 49

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
SCAB_1411 YP_003485938.1 AMP-binding NRPS ligase VFG0168 Protein 8e-93 48
SCAB_1411 YP_003485938.1 AMP-binding NRPS ligase VFG1817 Protein 2e-90 47
SCAB_1411 YP_003485938.1 AMP-binding NRPS ligase VFG0932 Protein 2e-87 45