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Name : pykF (SmuNN2025_0856) Accession : YP_003484774.1 Strain : Streptococcus mutans NN2025 Genome accession: NC_013928 Putative virulence/resistance : Virulence Product : pyruvate kinase Function : - COG functional category : G : Carbohydrate transport and metabolism COG ID : COG0469 EC number : - Position : 894077 - 895579 bp Length : 1503 bp Strand : + Note : similar to (nr):(gi|24379618|ref|NP_721573.1|), BLASTP E():0, 100.0% identity in 500 aa overlap. DNA sequence : ATGAATAAACGCGTAAAAATTGTTGCAACTTTAGGTCCAGCGGTAGAAATCCGTGGTGGTAAAAAATTTGGTGAAGATGG CTATTGGGGTGAAAAACTTGATGTTGAAGCTTCAGCAGCAAAAATTGCTGAATTGATTACAGAAGGAGCCAATGTTTTTC GTTTTAACTTTTCACATGGTGACCATGCTGAGCAAGGTGAACGTATGGCGACTGTACGTCGCGCGGAAGAATTGGCACGT CAAAAGGTTGGATTTCTTCTTGATACTAAAGGACCTGAAATGCGTACAGAATTGTTTGCAGATGGTGTCAAAGAATATGA ATATAAGACTGGTGATAAACTTCGTATAGCAACTAAACAAGGTATTGAATCAACTAAGGATGTCATTGCTTTAAATGTTG CAGGCGGTCTTGATATTTATGATGATGTTGCTGTCGGTCAGACTATTCTTATTGATGATGGGAAACTTGGCCTTACAGTA ACTGCTAAAGATATTACAACTCGCGAGTTTGAAGTAACCGTTGAAAATGATGGTATTATTGCTAAACAAAAAGGTGTCAA TATTCCTAATACTAAAATTCCTTTCCCAGCACTTGCTGAGCGTGATAATGCAGATATTCGCTTTGGTTTGGAACAAGGTC TTAACTTTATTGCTATTTCTTTTGTTCGTACTGCTAAGGATGTTAATGAAGTTCGTCAAATTTGTAAAGAAACAGGTAAC GAGCACGTAAAACTTTTTGCTAAAATTGAAAATCAACAAGGTATTGATAACATTGATGAAATCATTGATGCAGCTGACGG TATCATGATTGCTCGCGGTGACATGGGTATTGAAGTGCCGTTTGAAATGGTTCCAGTATATCAAAAAATGATTATCACGA AAGTTAATGCAGCAGGGAAGTCAGCTATCACAGCAACAAATATGCTTGAAACAATGACTGACAAACCACGTGCAACACGT TCCGAAGTCTCTGATGTCTTTAATGCTGTCATTGATGGTACTGATGCAACAATGCTTTCTGGTGAATCAGCTAATGGTAA GTATCCAGTTGAAGCTGTTCGTACCATGGCAACAATTGATAAGAATGCTCAAACACTTCTTAATGAATATGGCCGTTTGA ATTCAGATAATTTGCCACGTACCAACAAGACTGAAGTTGTCGCTTCAGCTGTTAAAGATGCGACTAAATCAATGGATATT AAATTGGTTGTTACAATTACGGAATCTGGTAACACAGCTCGTTTAATTTCAAAATACCGTCCGGATGCAGATATCTTAGC TTTAACATTTGATGAAAAAGTCCAAAAATCGTTGATGATTAACTGGGGAGTTATTCCAATCTTAACAGAAAAACCTGCAT CTACTGATGATATGTTTGAAATTGCAGAAAAAGCAGCTCTTAAATCAGGTTTGGTAGAGTCTGGTGACAACATCGTTATT GTTGCTGGTGTACCGGTTGGATCTGGTGGTACCAATACTATGCGTGTTCGTACCGTTCAATAA Protein sequence : MNKRVKIVATLGPAVEIRGGKKFGEDGYWGEKLDVEASAAKIAELITEGANVFRFNFSHGDHAEQGERMATVRRAEELAR QKVGFLLDTKGPEMRTELFADGVKEYEYKTGDKLRIATKQGIESTKDVIALNVAGGLDIYDDVAVGQTILIDDGKLGLTV TAKDITTREFEVTVENDGIIAKQKGVNIPNTKIPFPALAERDNADIRFGLEQGLNFIAISFVRTAKDVNEVRQICKETGN EHVKLFAKIENQQGIDNIDEIIDAADGIMIARGDMGIEVPFEMVPVYQKMIITKVNAAGKSAITATNMLETMTDKPRATR SEVSDVFNAVIDGTDATMLSGESANGKYPVEAVRTMATIDKNAQTLLNEYGRLNSDNLPRTNKTEVVASAVKDATKSMDI KLVVTITESGNTARLISKYRPDADILALTFDEKVQKSLMINWGVIPILTEKPASTDDMFEIAEKAALKSGLVESGDNIVI VAGVPVGSGGTNTMRVRTVQ |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| pykF | NP_805051.1 | pyruvate kinase | Not tested | SPI-2 | Protein | 3e-70 | 43 |
| pykF | CAA68205.1 | pyruvate kinase like protein | Not tested | SPI-2 | Protein | 2e-70 | 43 |
| STY1744 | NP_456147.1 | pyruvate kinase | Not tested | SPI-2 | Protein | 1e-69 | 43 |
| pykF | YP_216386.1 | pyruvate kinase | Not tested | SPI-2 | Protein | 3e-70 | 43 |
| Gene | GenBank Accn | Product | ID of source DB | Alignment Type | E-val | Identity |
| pykF | YP_003484774.1 | pyruvate kinase | VFG0479 | Protein | 1e-70 | 43 |
