Gene Information

Name : metB (SmuNN2025_0442)
Accession : YP_003484360.1
Strain : Streptococcus mutans NN2025
Genome accession: NC_013928
Putative virulence/resistance : Unknown
Product : cystathionine gamma-synthase
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0626
EC number : -
Position : 474679 - 475773 bp
Length : 1095 bp
Strand : +
Note : possible bifunctional enzyme, similar to (nr):(gi|24380053|ref|NP_722008.1|), BLASTP E():0, 99.7% identity in 364 aa overlap.

DNA sequence : 
ATGACTGAAGACTATAAATTAGATACTATTCTGGCACATGCAGGAATTAATACGGACAAGACAACAGGAGCTCTGACGGC
TCCTATTCATTTGTCAACAACTTATCAGCATCCTCAATTTGGTCAATCAACAGGTTTTGATTACACACGGACAAAAAATC
CTACCCGCACTGTTCTTGAAGAAACGCTGGCTAAAATTGAAAAGGCTAAATACGCTTTAGTAACATCGTCGGGTATGGCG
GCGCTTGTTTTGCTTTTTACTGGCTTTCCTATTGGGAGTAAGGTAGTTGCGGCGCGTGATTTATATGGTGGTTCTTTTCG
TTGGTTTAACGAACAGGAAAAAGCAGGAAGATTTTCTTTTGTTTACACCAATACAGAAACTGATATGATTGCTGCCATTT
CAGATGAGACCGATTATGTTTTTATCGAAACGCCAACCAATCCGCTCATGATTGAATTTGACATTAGTAAAGTTGCTCAA
GCAGCTCATAAGCATGGTGCCAAGGTCATTGTTGATAACACTTTTTACAGCCCTATTTATCAAAATCCGCTCGTTTTAGG
TGCTGATGTGGTTTTGCATTCAGCAACCAAGTATCTATCAGGTCATAATGATGTTCTTGCCGGTGTTTTAATGACTAGCG
ATCAAGAAATTTACGATAAGCTTTTTTATGACCAAAATACAACAGGTCCAACACTCTCGCCCTTAGATGCTTATTTGCTG
ATGCGCGGTCTGAAAACACTTAAATTGCGTATGGAAAAAGCAACACAAAATGCTAAGACAGTTGTTGCTTATTTAGAAAA
ATCACCTGCTGTTAAAGAGGTACTTTATACAGGAAAAGGCGGAATGATTTCTTTTAAAGTTGTGGATGAAAAAAAAATTC
CGCAAATTCTCAATCATTTACAGCTGTTCACCTTTGCAGAAAGTTTAGGTGGCGTTGAAAGTTTAATTACTTATCCAGCG
ACACAGACACACTTGGATATACCGGAGGAAGTGCGTCATTCCTATGGTTTGACAGATGACTTACTGCGTCTGTCCATTGG
AATTGAAGATGCGGAAGACTTGATTGATGATTTAAAAGCTGCTTTAGAAGCTTAA

Protein sequence : 
MTEDYKLDTILAHAGINTDKTTGALTAPIHLSTTYQHPQFGQSTGFDYTRTKNPTRTVLEETLAKIEKAKYALVTSSGMA
ALVLLFTGFPIGSKVVAARDLYGGSFRWFNEQEKAGRFSFVYTNTETDMIAAISDETDYVFIETPTNPLMIEFDISKVAQ
AAHKHGAKVIVDNTFYSPIYQNPLVLGADVVLHSATKYLSGHNDVLAGVLMTSDQEIYDKLFYDQNTTGPTLSPLDAYLL
MRGLKTLKLRMEKATQNAKTVVAYLEKSPAVKEVLYTGKGGMISFKVVDEKKIPQILNHLQLFTFAESLGGVESLITYPA
TQTHLDIPEEVRHSYGLTDDLLRLSIGIEDAEDLIDDLKAALEA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAS0418 YP_042545.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 3e-62 43
SAR0460 YP_039909.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 3e-61 43