Gene Information

Name : clp (SmuNN2025_1073)
Accession : YP_003484991.1
Strain : Streptococcus mutans NN2025
Genome accession: NC_013928
Putative virulence/resistance : Virulence
Product : Clp-like ATP-dependent protease ATP-binding subunit
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0542
EC number : -
Position : 1123553 - 1125658 bp
Length : 2106 bp
Strand : +
Note : similar to (nr):(gi|24379399|ref|NP_721354.1|), BLASTP E():0, 99.9% identity in 700 aa overlap.

DNA sequence :
ATGGCAAATTTTAATGGACGCGATCCTTTTGGAAATATGGACGATATTTTTAATCAATTAATGGGTAATATGGGGGGATA
CAACTCTGAAAACCGTCGATATTTGATTAACGGTCGTGAAGTAAGTCCCGAAGAATTCGCACAATACAGACAAACAGGTA
AGCTTCCTGGCAATCCAGAAATACAGCAAGCTCAAGCTGCTGCTAGAACTCCAAAAGAAGACAGTATTTTGACTAAGCTT
GGTAACAATTTAACCGAAGAAGCCAGACAAGGTAACCTTGATCCTGTTATTGGACGGAATAAAGAAATTCAAGAAACTGC
TGAGATCTTAGCTCGGCGGACTAAAAACAATCCTGTTCTGGTCGGTGATGCCGGTGTTGGTAAAACAGCTGTCGTTGAAG
GCTTAGCACAGGCTATTGTTAACGGTGATGTCCCTGCCAGTATTAAAAATAAGGAAGTTATTTCTATTGATATTTCAGGA
TTAGAAGCTGGTACACAATACCGCGGTGCTTTCGAAGAAAATATTCAAAACTTGGTTAAAGAAGTCAAAGAAGCTGGCAA
TATCATCCTCTTCTTTGATGAAATTCATCAAATTTTAGGTGCTGGTTCAACTGGTGGTGACAGTGGTTCTAAAGGTTTGG
CAGACATTATCAAACCTGCTTTATCTCGCGGTGAATTGACTGTTATCGGTGCTACTACGCAAGATGAATACCGCAATACC
ATTATGAAAAACGCTGCATTGGCACGTCGTTTCAACGAAGTCAAAGTAAATGCACCTTCTGCTGAGGATACTTACGAAAT
TTTAAAAGGTATTTCAGCTCTCTACGAACAACATCATAATGTTATTTTGCCTAAGGAAGTTTTAAAAGCTGCTGTTGACT
TATCCGTACAATACATCCCGCAACGCAGTCTGCCTGATAAGGCCATTGACCTTGTTGATATGACAGCTGCTCATCTGGCT
GCTCAACATCCAGCAACTGATGTTAAGACACTTGAAAAAGAAATTCAAACTGAAAAAGATAAACAACAAGCTGCTGCTGA
AAAAGAAGATTATGAGGAAGCTCTTAAATCAAAAACTAAAATTGATAAACTGCAAGCACAAATTGACAATCATACTGAAG
GGCAAAAGGTCACTGCTACTATCAACGATGTGGCTGAGGCAGTTGAACGTTTGACAGGTATCCCTGTTTCGCAAATGGGA
AGCAGTGACATTGAACGTCTAAAAGAAATGAATTCTCGTCTCAAAGGCAAAGTTATTGGTCAAGATGAAGCTGTTGAAGC
TGTTTCACGCGCTATTCGCCGTAACCGTGCTGGTTTTGATGAAGGCAACCGTCCAATCGGCAGTTTCCTTTTTGTCGGAC
CTACTGGTGTTGGTAAAACAGAATTGGCTAAGCAGTTAGCCTTGGATATGTTTGGTTCTAAAGACTCTATTATCCGTCTT
GATATGTCAGAGTACAGTGATCGTACAGCTGTTTCCAAATTGATTGGTACTACTGCCGGTTATGTCGGCTATGATGATAA
CAGCAATACATTGACTGAACGTGTTCGCCGCAATCCTTATTCTATCGTTTTACTTGATGAGATTGAAAAGGCTGACTCTC
AAGTCATCACTCTTCTCCTTCAAGTATTGGATGATGGTCGTTTGACAGACGGACAAGGTAATACCATTAACTTTAAGAAT
ACCGTGATTATTGCAACTTCTAATGCTGGTTTTGGTAATGAAACCTTAACTGGTCAGGAAGATAAGGACATGAAGATCAT
GGATCGCATTGCCCCTTACTTCCGTCCCGAGTTTTTAAACCGTTTCAATGCAGTCATTGAATTCTCTCACTTAAGCAAAG
AAGACTTGGATGAAATTGTTAATCTCATGCTATCTGAAGTGAATACCACGCTTGCTAAGAAAGGAATTGATCTTGTTGTC
AGTGACAGCGCCAAGGCACATTTGATTGAAGAAGGTTATGACGAAGCAATGGGTGTTCGTCCATTACGCCGAGTTATCGA
GCAAGAAATTCGTGATAAAGTAACTGACTTCTATCTTGATCATACAGATGTTAAACATCTCAAAGCTGAAATGCAAGATG
ATAAATTGATTATTGAAGAAACTTAA

Protein sequence :
MANFNGRDPFGNMDDIFNQLMGNMGGYNSENRRYLINGREVSPEEFAQYRQTGKLPGNPEIQQAQAAARTPKEDSILTKL
GNNLTEEARQGNLDPVIGRNKEIQETAEILARRTKNNPVLVGDAGVGKTAVVEGLAQAIVNGDVPASIKNKEVISIDISG
LEAGTQYRGAFEENIQNLVKEVKEAGNIILFFDEIHQILGAGSTGGDSGSKGLADIIKPALSRGELTVIGATTQDEYRNT
IMKNAALARRFNEVKVNAPSAEDTYEILKGISALYEQHHNVILPKEVLKAAVDLSVQYIPQRSLPDKAIDLVDMTAAHLA
AQHPATDVKTLEKEIQTEKDKQQAAAEKEDYEEALKSKTKIDKLQAQIDNHTEGQKVTATINDVAEAVERLTGIPVSQMG
SSDIERLKEMNSRLKGKVIGQDEAVEAVSRAIRRNRAGFDEGNRPIGSFLFVGPTGVGKTELAKQLALDMFGSKDSIIRL
DMSEYSDRTAVSKLIGTTAGYVGYDDNSNTLTERVRRNPYSIVLLDEIEKADSQVITLLLQVLDDGRLTDGQGNTINFKN
TVIIATSNAGFGNETLTGQEDKDMKIMDRIAPYFRPEFLNRFNAVIEFSHLSKEDLDEIVNLMLSEVNTTLAKKGIDLVV
SDSAKAHLIEEGYDEAMGVRPLRRVIEQEIRDKVTDFYLDHTDVKHLKAEMQDDKLIIEET

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
clpC YP_005163377.1 ATP-dependent Clp protease ATP-binding subunit Not tested Not named Protein 7e-135 45

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
clp YP_003484991.1 Clp-like ATP-dependent protease ATP-binding subunit VFG0080 Protein 9e-153 48
clp YP_003484991.1 Clp-like ATP-dependent protease ATP-binding subunit VFG0079 Protein 4e-141 45