Gene Information

Name : guaA (SmuNN2025_0970)
Accession : YP_003484888.1
Strain : Streptococcus mutans NN2025
Genome accession: NC_013928
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : -
Position : 1012504 - 1014105 bp
Length : 1602 bp
Strand : -
Note : similar to (nr):(gi|24379503|ref|NP_721458.1|), BLASTP E():0, 99.6% identity in 517 aa overlap.

DNA sequence :
ATGTCTTTTACTAGTAAGCCTAGTAAAACTGTAGAAGAAAGGGAGATAATGACTGATATTAAAGATATTCAAAAAATTAT
CGTACTTGACTACGGCAGTCAGTACAATCAGCTGATCGCACGCCGCATTCGTGAATTTGGTATTTTTTCTGAATTGAGAA
GCCATAAGGTAACAGCCGACGAAGTCCGTGCTATCAATCCAATTGGTATTGTCCTTTCAGGAGGACCAAGTTCAGTTTAT
GCTGAAGATGCCTTTGACATTGATAAGGAAATCCTTGATCTTGGAATCCCCGTTTTAGGTATTTGTTATGGTATGCAGCT
TCTTACAGAAAAACTTGGCGGTAAAGTTGTTCCTGCTGGACAAACTGGCAATAGTGAATATGGTCAGTCTACCCTTCATT
TGACAGAAAATTCAGAGCTTTTTAAGGAAACTCCTGCTGAACAAACTGTTTTGATGAGCCATGGCGATGCTGTTACTGAA
ATTCCCGAAGGCTTTCAATTGGTTGGCGAATCAAGCGACTGCCCTTATGCTGCCATTGAAAATGTCGAAAAGAAAATCTT
TGGCATTCAATTTCACCCAGAAGTTCGTCATACGGAATATGGTAATGCGATTTTACGCAATTTTGCTTTTAATGTTTGTA
AAGCCAAAGGTGATTGGTCAATGGACAGTTTCATTGATATGGAAATTGAAAAAATCCGTGAACAAGTTGGTAATCGTAAG
GTTCTTCTGGGGCTTTCGGGCGGTGTGGACTCTTCTGTTGTTGGCGTGCTTTTGCAAAAAGCTATAGGTGACCAATTAAC
CTGTATCTTCGTTGATCATGGCCTTCTTCGTAAGGGTGAAGGCGATCAGGTTATGGAAATGTTGGGTGGTAGATTTGGAC
TCAATATTATTCGTGTTGATGCTTCCAAACGCTTTTTGGATCTTCTTGCTGGTATTGATGATCCTGAGAAAAAGCGTAAA
ATCATTGGGAATGAATTTGTCTATGTTTTTGATGATGAAGCCAGCAAACAAAAAGGCGTTGATTTCTTGGCACAAGGAAC
GCTTTATACAGATGTCATCGAATCCGGCACAGAAACAGCCCAAACCATTAAATCACACCACAATGTCGGTGGTCTTCCAG
AAGACATGCAGTTTGAATTAATAGAGCCGTTAAACACACTGTTCAAGGATGAAGTTCGTACTCTGGGGACTGCTTTGGGA
ATGCCAGATGAAATTGTTTGGCGGCAGCCCTTCCCAGGACCTGGACTTGCTATTCGTGTGATGGGAGAAATTACTGCTGA
AAAACTTGAAACGGTTCGTGAATCTGACGCTATTTTACGCGAAGAAATTGCTGCAGCAGGTCTGAATCGTGACATTTGGC
AATATTTTACTGTCAATACTGGCGTTCGTTCAGTCGGAGTTATGGGAGATGGTCGTACCTATGACTATACCATCGCTATT
CGCGCCATCACTTCTATTGACGGCATGACAGCAGACTTTGCCCGTATTCCTTGGGAGGTTCTCCAAAAGATCTCTGTTCG
TATTGTCAACGAAGTGAAACACGTCAACCGCATCGTCTACGACATTACCAGCAAACCACCAGCAACCGTTGAGTGGGAAT
AA

Protein sequence :
MSFTSKPSKTVEEREIMTDIKDIQKIIVLDYGSQYNQLIARRIREFGIFSELRSHKVTADEVRAINPIGIVLSGGPSSVY
AEDAFDIDKEILDLGIPVLGICYGMQLLTEKLGGKVVPAGQTGNSEYGQSTLHLTENSELFKETPAEQTVLMSHGDAVTE
IPEGFQLVGESSDCPYAAIENVEKKIFGIQFHPEVRHTEYGNAILRNFAFNVCKAKGDWSMDSFIDMEIEKIREQVGNRK
VLLGLSGGVDSSVVGVLLQKAIGDQLTCIFVDHGLLRKGEGDQVMEMLGGRFGLNIIRVDASKRFLDLLAGIDDPEKKRK
IIGNEFVYVFDDEASKQKGVDFLAQGTLYTDVIESGTETAQTIKSHHNVGGLPEDMQFELIEPLNTLFKDEVRTLGTALG
MPDEIVWRQPFPGPGLAIRVMGEITAEKLETVRESDAILREEIAAAGLNRDIWQYFTVNTGVRSVGVMGDGRTYDYTIAI
RAITSIDGMTADFARIPWEVLQKISVRIVNEVKHVNRIVYDITSKPPATVEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 1e-174 70
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 8e-175 70
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 7e-175 70
guaA NP_938969.1 GMP synthase Not tested Not named Protein 4e-120 51