Gene Information

Name : Nmag_2605 (Nmag_2605)
Accession : YP_003480726.1
Strain : Natrialba magadii ATCC 43099
Genome accession: NC_013922
Putative virulence/resistance : Virulence
Product : pyruvate kinase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0469
EC number : 2.7.1.40
Position : 2686344 - 2688110 bp
Length : 1767 bp
Strand : +
Note : TIGRFAM: pyruvate kinase; KEGG: hmu:Hmuk_2510 pyruvate kinase; PFAM: pyruvate kinase barrel; pyruvate kinase alpha/beta

DNA sequence :
ATGAGAAACGCAAAGATCGTCTGTACGCTGGGTCCCGCCTCGAGCGATCAGCGGACGATCCGCGACCTCGCCGACGCCGG
GATGTCCGTCGCCCGGCTGAACGCGAGCCACGGTAGCCGCGCGGACCGAGCCGAACTCATCGACCGCGTCCGGACGGTCG
ACGAGCAACGCGAGAAGCCAGTCGCCGTCATGCTCGACATGCAGGGCCCCGAGATTCGCACCGCCCCGCTTCCTGACGGC
GAAACGGTGACACTCGAGTCCGGCTCCGAAATCGAGTTCGTCGAGAGCGACCAGGTCTCGGCCGAACGGGTGGGGCTCTC
GCTGCCGATCGACGCCGTCGAAGTGGGTGATCGTATTTTGCTCGACGACGGATTGATCGAGACGACAGTTCGCGAGCACG
AGGACGAGGGCGACACGATACGGGCACACGTCGACACGGGCGGCGAACTCGGCGGCCGGAAGGGTGTGAACGTCCCCGGC
GTCGATCTGGACCTCGATGTCGTCACCGAGTCCGACCGTCGGGACCTGGAACTGGCCGCCGAGAAGGAGGTCGACTTCGT
CGCGGCGAGTTTCGTCCGTGACGCCGAAGACGTCTTCGAGGTTAGCGAGGTACTCGAGAGTTTCGGCGCGGAGATCCCGA
TCGTATCGAAGATCGAGCGCGCAGGTGCGGTAGACAACTTGGACGAGATCATCGACGCGTCGGACGGAATCATGGTTGCC
CGCGGCGATCTGGGCGTCGAGTGTCCGATGGAGGACGTGCCGATGATCCAGAAGCGAATGATCCGGAAGTGTCGCGAGGC
AGGCCTGCCGGTTATTACGGCGACGGAGATGCTGGACTCGATGGTTCACGCGCGCCGACCGACGAGAGCGGAGGCCTCGG
ACGTGGCCAACGCCGTTCTCGACGGCACGGATGCGGTGATGCTCTCGGCGGAGACCGCCATCGGCGACCACCCTGTCGCC
GTCGTCGACGCGATGGACAGTATCGTCCGCGAGGTCGAGAACTCTGGGGAGTACGACGAACTGTTAGAACAGCGCGTTCC
CGCGGCCGGCGAGGCCCGAACGGACGCGCTGGCACGATCGGCTCGCTTCCTTGCACGCGACGTTGGCGCCGACGCAGTCG
TCGCGGCAACCGAATCTGGCTACACGGCATTGAAGACCGCGAAGTACCGGCCCGGTGTTCCGGTCGTCGCCTCGACGCCG
AGCCACCGCGTTCGGCGGAAACTCGCCCTCTCGTGGGGCGTCACGCCGCTGTATGCCGAAATCTCCGATCAGGGGGCTGA
TACCGTCGTCGAGAAGGCAGTACAGGCAGCACTCGAGGCCGGGATCGCCGAGAGCGGTGCCACCGTCGTTGTTCTCTGTG
GGATGATGACCGAACTCGAGGGTGCGAGCACGACGAACATGTTGAAGGTCCACGTCGCCGCGGAGGCACTGACGACGGGC
CGTGTCGTCGTCGAGGGCCGAGCCACGGGACCGCTCGCCCGCGTCCCGGACGGCGACCTCACCGACGTGCCGGACGGTGC
TATCATCGCTCTCCCAGCGGATTTCGACGAGGAGTTCACGGGTGATTTGAACACGATTGGTGGCATCGTCAACGCCCAGC
GTGGGATGACGGGGTACCCGGCACTGGTCGCCCGAGAGATCAACGTGCCGATGGTCAGTGGGGCAGATATTCCGGATGCT
GCTTCCGGAACCGTCGTGACCGTCGACGCAGAGCGTGGCGTCGTCTACGAAGGTAACATCAGTGACCGGCGCAACCAGGA
CGAGTAA

Protein sequence :
MRNAKIVCTLGPASSDQRTIRDLADAGMSVARLNASHGSRADRAELIDRVRTVDEQREKPVAVMLDMQGPEIRTAPLPDG
ETVTLESGSEIEFVESDQVSAERVGLSLPIDAVEVGDRILLDDGLIETTVREHEDEGDTIRAHVDTGGELGGRKGVNVPG
VDLDLDVVTESDRRDLELAAEKEVDFVAASFVRDAEDVFEVSEVLESFGAEIPIVSKIERAGAVDNLDEIIDASDGIMVA
RGDLGVECPMEDVPMIQKRMIRKCREAGLPVITATEMLDSMVHARRPTRAEASDVANAVLDGTDAVMLSAETAIGDHPVA
VVDAMDSIVREVENSGEYDELLEQRVPAAGEARTDALARSARFLARDVGADAVVAATESGYTALKTAKYRPGVPVVASTP
SHRVRRKLALSWGVTPLYAEISDQGADTVVEKAVQAALEAGIAESGATVVVLCGMMTELEGASTTNMLKVHVAAEALTTG
RVVVEGRATGPLARVPDGDLTDVPDGAIIALPADFDEEFTGDLNTIGGIVNAQRGMTGYPALVAREINVPMVSGADIPDA
ASGTVVTVDAERGVVYEGNISDRRNQDE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
pykF YP_216386.1 pyruvate kinase Not tested SPI-2 Protein 9e-69 42
pykF NP_805051.1 pyruvate kinase Not tested SPI-2 Protein 9e-69 42
STY1744 NP_456147.1 pyruvate kinase Not tested SPI-2 Protein 8e-69 42
pykF CAA68205.1 pyruvate kinase like protein Not tested SPI-2 Protein 3e-68 42

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Nmag_2605 YP_003480726.1 pyruvate kinase VFG0479 Protein 4e-69 42