Gene Information

Name : Thit_0811 (Thit_0811)
Accession : YP_003476651.1
Strain : Thermoanaerobacter italicus Ab9
Genome accession: NC_013921
Putative virulence/resistance : Unknown
Product : DNA polymerase I
Function : -
COG functional category : L : Replication, recombination and repair
COG ID : COG0749
EC number : -
Position : 874860 - 877478 bp
Length : 2619 bp
Strand : +
Note : TIGRFAM: DNA polymerase I; PFAM: DNA-directed DNA polymerase; 5'-3' exonuclease, SAM-fold domain; 3'-5' exonuclease; 5'-3' exonuclease, N-terminal resolvase-like domain; KEGG: tpd:Teth39_1474 DNA polymerase I; SMART: 5'-3' exonuclease; DNA-directed DNA po

DNA sequence :
ATGTATAAATTTTTAATAATTGATGGAAGTAGCCTCATGTACAGAGCCTATTATGCCTTGCCCATGCTTACTACAAGTGA
GGGATTGCCTACAAATGCTCTGTATGGTTTTACTATGATGCTTATAAAACTTATCGAGGAGGAAAAACCTGATTACATAG
CTATTGCTTTTGACAAAAAAGCTCCTACTTTTAGACACAAAGAATATCAAGACTACAAAGCTACAAGACAAGCTATGCCT
GAAGAACTTGCTGAACAAGTAGACTATTTGAAAGAAATTATAGATGGCTTTAATATAAAGACATTAGAATTAGAAGGTTA
TGAAGCTGATGACATTATAGGGACTATTTCAAAGCTGGCAGAGGAAAAAGGAATGGAAGTGCTTGTAGTTACAGGAGACA
GAGATGCTCTTCAATTAGTTTCAGATAAAGTGAAGATAAAAATTTCTAAAAAGGGTATTACTCAGATGGAAGAGTTTGAC
GAAAAGGCTATTTTAGAAAGGTATGGAATAACTCCTCAGCAGTTTATAGATTTAAAAGGGCTTATGGGAGATAAATCTGA
TAATATCCCTGGAGTACCTAATATAGGGGAAAAAACTGCGATTAAGCTATTAAAGGATTTTGGAACAATTGAAAATTTAA
TCCAAAATCTTTCTCAGCTTAAAGGTAAAATAAAAGAAAATATAGAAAACAATAAAGAGTTAGCTATAATGAGTAAGAGG
CTTGCTACTATAAAAAGAGACATTCCCATTGAGATAGATTTTGAGGAGTATAAAGTAAAAAAATTTAATGAGGAGAAGCT
TTTAGAGCTTTTTAATAAATTAGAATTCTTTAGTTTAATTGATAACATAAAGAAAGAAAGTAGCATAGAGATTGTAGATA
ATCATAAAGTTGAAAAATGGTCAAAAGTAGATATAAAAGAATTAGTAACTTTGTTGCAAGATAACAGAAATATTGCTTTT
TACCCGTTAATTTATGAAGGGGAAATAAAAAAAATAGCCTTTTCTTTTGGAAAGGATACGGTTTATATTGACGTTTTCCA
AACAGAAGATTTAAAGGAGATTTTTGAAAAAGAAGATTTTGAATTTACAACCCATGAAATAAAGGATTTTTTAGTGAGGC
TTTCTTATAAAGGAATAGAGTGTAAAAGCAAGTACATAGATACTGCTGTAATGGCTTATCTTCTGAATCCTTCTGAGTCT
AACTATGACTTAGACCGTGTGCTAAAAAAATATTTAAAGGTAGATGTGCCTTCTTATGAAGGAATATTTGGCAAAGGTAG
GGATAAAAAGAAAATTGAAGAGATTGACGAAAACATACTTGCTGATTATATTTGCAGTAGATGTGTGTATCTATTTGATT
TAAAAGAAAAGCTGATGAATTTTATTGAAGAGATGGATATGAAAAAACTTCTATTAGAAATAGAAATGCCTCTTGTAGAA
GTTTTAAAATCAATGGAGGTAAGTGGTTTTACATTGGATAAAGAAGTTCTAAAAGAGCTTTCACAAAAGATAGATGATAG
AATAGGAGAAATACTAGATAAAATTTATAAAGAGGCAGGATATCAATTTAATGTAAATTCACCTAAGCAATTAAGTGAAT
TTTTGTTTGAAAAGTTAAACTTACCAGTAATAAAGAAAACAAAAACAGGATACTCTACGGATTCTGAAGTTTTGGAACAA
TTGGTTCCTTATAATGATATTGTCAGCGATATAATAGAGTATCGGCAACTTACAAAACTTAAATCTACTTATATAGATGG
ATTTTTGCCTCTTATGGATGAAAACAATAGAGTACATTCTAATTTTAAACAAATGGTTACTGCTACAGGTAGAATAAGCA
GCACCGAGCCAAATCTACAAAATATACCTATAAGAGAAGAGTTTGGCAGACAAATTAGAAGGGCTTTTATTCCGAGGAGT
AGAGATGGATATATTGTTTCAGCAGATTATTCTCAGATTGAACTGAGGGTTTTAGCACATGTTTCGGGAGATGAAAAGCT
AATAGAATCTTTTATGAATAATGAAGATATACATTTAAGGACAGCTTCGGAGGTTTTTAAAGTTCCTATGGAAAAAGTTA
CACCGGAGATGAGAAGAGCAGCAAAAGCCGTAAATTTTGGCATAATATATGGCATAAGCGATTATGGGCTTTCTCGAGAC
CTTAAAATATCAAGAAAAGAAGCAAAAGAGTACATAAATAATTATTTTGAAAGATATAAAGGAGTAAAAGAATATATTGA
AAAAATAGTACGATTTGCAAAAGAAAATGGCTATGTGACTACAATAATGAACAGAAGAAGATATATTCCTGAAATAAACT
CAAGAAATTTTACTCAAAGATCGCAGGCCGAAAGGTTAGCAATGAATGCTCCGATACAGGGAAGTGCGGCTGATATAATA
AAAATGGCAATGGTTAAGGTATACAACGATTTAAAAAAATTAAAGCTTAAGTCTAAGCTTATATTGCAAGTTCATGACGA
GCTTGTAGTGGATACTTATAAGGATGAAGTAGATATCATAAAAAAGATACTTAAAGAAAATATGGAAAATGTAGTGCAAT
TAAAAGTTCCTCTGGTTGTTGAAATTGGCGTAGGGCCTAATTGGTTTTTGGCCAAGTGA

Protein sequence :
MYKFLIIDGSSLMYRAYYALPMLTTSEGLPTNALYGFTMMLIKLIEEEKPDYIAIAFDKKAPTFRHKEYQDYKATRQAMP
EELAEQVDYLKEIIDGFNIKTLELEGYEADDIIGTISKLAEEKGMEVLVVTGDRDALQLVSDKVKIKISKKGITQMEEFD
EKAILERYGITPQQFIDLKGLMGDKSDNIPGVPNIGEKTAIKLLKDFGTIENLIQNLSQLKGKIKENIENNKELAIMSKR
LATIKRDIPIEIDFEEYKVKKFNEEKLLELFNKLEFFSLIDNIKKESSIEIVDNHKVEKWSKVDIKELVTLLQDNRNIAF
YPLIYEGEIKKIAFSFGKDTVYIDVFQTEDLKEIFEKEDFEFTTHEIKDFLVRLSYKGIECKSKYIDTAVMAYLLNPSES
NYDLDRVLKKYLKVDVPSYEGIFGKGRDKKKIEEIDENILADYICSRCVYLFDLKEKLMNFIEEMDMKKLLLEIEMPLVE
VLKSMEVSGFTLDKEVLKELSQKIDDRIGEILDKIYKEAGYQFNVNSPKQLSEFLFEKLNLPVIKKTKTGYSTDSEVLEQ
LVPYNDIVSDIIEYRQLTKLKSTYIDGFLPLMDENNRVHSNFKQMVTATGRISSTEPNLQNIPIREEFGRQIRRAFIPRS
RDGYIVSADYSQIELRVLAHVSGDEKLIESFMNNEDIHLRTASEVFKVPMEKVTPEMRRAAKAVNFGIIYGISDYGLSRD
LKISRKEAKEYINNYFERYKGVKEYIEKIVRFAKENGYVTTIMNRRRYIPEINSRNFTQRSQAERLAMNAPIQGSAADII
KMAMVKVYNDLKKLKLKSKLILQVHDELVVDTYKDEVDIIKKILKENMENVVQLKVPLVVEIGVGPNWFLAK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
polA YP_281523.1 DNA polymerase I Not tested Not named Protein 1e-147 41