Gene Information

Name : Thit_0566 (Thit_0566)
Accession : YP_003476429.1
Strain : Thermoanaerobacter italicus Ab9
Genome accession: NC_013921
Putative virulence/resistance : Unknown
Product : GMP synthase, large subunit
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : -
Position : 612252 - 613790 bp
Length : 1539 bp
Strand : +
Note : KEGG: tpd:Teth39_1719 GMP synthase; TIGRFAM: GMP synthase, large subunit; GMP synthase, small subunit; PFAM: GMP synthase domain protein; tRNA methyl transferase-like; glutamine amidotransferase class-I

DNA sequence :
ATGGGGATTAAACGGGAAGTAGTGTTAGTTTTAGATTTTGGAGGCCAATACACACAATTAATAGCGAGGAGAATAAGAGA
AGCAAATGTCTTTTGCGAGATTGTTCCTTACAATATTTCTCCAGAGGAAGTACGAAAAAAAGAGCCAAAGGGAATTGTTC
TTTCTGGAGGACCTGCTAGTGTCTATGCAAAAAATGCTCCTAAATGCGATAAGGGAATTTTCGAATTAGGATATCCTGTG
CTAGGTATATGTTATGGTGCACAACTTATGACAGAGCTTTTAGGTGGAAAAGTTGCTCCAGCACCTGTGAAGGAATATGG
CAAGACAGAAATTGTTTTAAACAATACTATCCCTTTGTTTAAAGGCATAGAAAGAGACACTATTGTTTGGATGAGTCATA
CTGATCACATAGAACTTCCCCCTCCAGATTTTAAGGTGGTAGCTTCTACTGACAATTGCCCAATTGCAGCTATTGCGAAT
GTAGAAAAGAAATTGTACGCAGTTCAATTCCATCCTGAAGTTTCACATACCCATAGAGGAACAGAGATCATAAGAAATTT
CTTATTTGAAGTATGTGATTGCGCGGCAGATTGGACAATGGATTCTTTGATTGAGCAGACAGTAAAAGAAATAAAAGCAA
AAGTAGGAAAACACAAAGCTGTATGCGCTCTGTCTGGTGGTGTAGATTCTTCGGTTGCTGCTGTTTTAGTAGACAGAGCC
ATTCACGACCAATTGGTGTGCATTTTTGTTGATACTGGGCTTTTAAGGAAAAATGAAGGAGATATGGTTATCGAAACTTT
TAGAAAGAATTATGACATGAACATAATCCGGGTAGATGCAAAGGATAGATTTTTGTCACGGCTTAAAGGAGTTACGGATC
CAGAAGAAAAGAGAAAAATTATTGGTAATGTTTTTATAGAAGTTTTTAAAGAAGAAGCTTTAAAAATAGGAGACGTTAAG
TTTTTGGTGCAAGGGACTTTGTATCCTGATGTAATAGAAAGTGGCAATGGTGTATCTTCCACTATTAAAAGCCATCACAA
TGTGGGAGGTTTGCCTGAAGATATAGGCTTTGAACTTATTGAACCTTTGAAAATGCTTTTTAAAGATGAAGTGAGGCAAG
TAGGAAAAGAATTAGGAATTCCTGAGGAAATATTATATAGGCAGCCATTCCCCGGCCCAGGCCTTGCAGTCAGGATCCTC
GGAGAAGTTACAGAAGAAAAGTTAGAAATTTTAAGGCAAGCTGACAGCATAGTTCTAAGAGAGATGAAAAAATTTGGCTG
GTATAATAAAGTGTGGCAATCTTTTGCAGTTTTGCCTGGCGTAAAAAGTGTTGGAGTTATGGGAGATGAAAGAACTTACG
CTTATGCCATAATTTTGAGGGTAGTAGATAGCTACGATGGAATGACAGCGGATTGGACAAAGCTTCCTTATGAAATTTTG
GAAAGCATATCAACAAGCATTACTAATGAAGTCCCAGGAGTAAACAGAGTGCTTTACGATATTACTTCAAAGCCTCCAGC
AACCATAGAGTGGGAATAA

Protein sequence :
MGIKREVVLVLDFGGQYTQLIARRIREANVFCEIVPYNISPEEVRKKEPKGIVLSGGPASVYAKNAPKCDKGIFELGYPV
LGICYGAQLMTELLGGKVAPAPVKEYGKTEIVLNNTIPLFKGIERDTIVWMSHTDHIELPPPDFKVVASTDNCPIAAIAN
VEKKLYAVQFHPEVSHTHRGTEIIRNFLFEVCDCAADWTMDSLIEQTVKEIKAKVGKHKAVCALSGGVDSSVAAVLVDRA
IHDQLVCIFVDTGLLRKNEGDMVIETFRKNYDMNIIRVDAKDRFLSRLKGVTDPEEKRKIIGNVFIEVFKEEALKIGDVK
FLVQGTLYPDVIESGNGVSSTIKSHHNVGGLPEDIGFELIEPLKMLFKDEVRQVGKELGIPEEILYRQPFPGPGLAVRIL
GEVTEEKLEILRQADSIVLREMKKFGWYNKVWQSFAVLPGVKSVGVMGDERTYAYAIILRVVDSYDGMTADWTKLPYEIL
ESISTSITNEVPGVNRVLYDITSKPPATIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 3e-148 57
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 3e-148 57
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 3e-148 57
guaA NP_938969.1 GMP synthase Not tested Not named Protein 3e-135 53