Gene Information

Name : Thit_2272 (Thit_2272)
Accession : YP_003478044.1
Strain : Thermoanaerobacter italicus Ab9
Genome accession: NC_013921
Putative virulence/resistance : Unknown
Product : homoserine dehydrogenase
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0460
EC number : 1.1.1.3
Position : 2320039 - 2321295 bp
Length : 1257 bp
Strand : -
Note : KEGG: tpd:Teth39_0140 homoserine dehydrogenase; PFAM: homoserine dehydrogenase; amino acid-binding ACT domain protein; homoserine dehydrogenase NAD-binding

DNA sequence :
ATGAAAATAGGACTAATGGGGCTTGGCACAGTTGGAACAGGCGTAGTTCATTTAATAAACCAAAACGGTAAAAACATTGA
AAAAAAGTTGGGGGAAAAAATTGAGATAAAGAAGATACTTGTAAAAGACCCTAATAAAAAAAGGGCATCCTTTGCAGAAG
GGAAAATAACTTTTGATGCAAACGACATTTTAGAAGATGAAGAAATAGATGTAGTGGTTGAGGTGATGGGGAAAGAACAT
CCTGCTTTGGAATATATCATAAAAGCCCTTAAGAAAGGCAAGCATGTCGTCACTGCTAACAAAGAAGTTATAGCAGTTCA
CGGGAAAGAGCTAATAAAACTTGCAACTGAAAATAAAGTAAATCTTCTCTATGAGGCATCAGTTGGTGGAGGCATTCCAA
TTATCAGGCCATTAAAACAATGTCTTGCGGCGAATAAAATATACGAAATCAAAGGAATATTAAATGGAACTACAAATTAT
ATATTGACAGAAATGAAAGAAAAAGGTTTAGACTTTGAAGAAGCTTTAAAAGAGGCTCAGCAAAAAGGTTATGCAGAAGC
AGACCCCACAGATGACGTGGAAGGTTTCGATGCGGCAAGAAAACTTGCTATACTCTGCACTTTAGCATTTAACAAATTCA
TTTTGCCTGAAAAAATTTACACAAAAGGTATAAAGTCCATTTCTAAATCTGACATAAAATATGCCGAAGAATTGGGGTAC
CATGTAAAACTCATAGCTTATGCAAAAATTGACGAAAACGAGCGATTAGAAGCATGGGTACATCCTGTTATGATAAAAAA
AGACAATCCTTTAAGCAGCGTAAATGGAGTCTTTAACGCTATTTTAGTTGACGGAAATGCGGTAGGTGAAGTCATGTTTT
ATGGGCAAGGAGCGGGTATGATGCCTACTGCTAGTGCGGTTGTTGCAGACATAATGGATGTGAAAAACCACATTGTAATT
CAAAATGGCTGCGAGGATGCGGACCTTCTTCCTGTTGTGGATACTGCATCCAAATATTATATAAGACTCATAGCCATTGA
TAAACCTGGTGTAATGAGCAAAATTACTGGAATATTAGGAGACAAAGGGATAAGTCTTTTATCGGTGGTGCAAAAAGGGG
TTTTGAAAGATACTGCAGAGATTGTTTTGATTACTCATATTGCGAATACAGGGAAGGTGTTTGAAGCTTTAGATGAAATA
CAAAACATGAAAGAAGTAGAAAGCATAGAAAGCGTCATAAGAGTAGAGGAGGAATAA

Protein sequence :
MKIGLMGLGTVGTGVVHLINQNGKNIEKKLGEKIEIKKILVKDPNKKRASFAEGKITFDANDILEDEEIDVVVEVMGKEH
PALEYIIKALKKGKHVVTANKEVIAVHGKELIKLATENKVNLLYEASVGGGIPIIRPLKQCLAANKIYEIKGILNGTTNY
ILTEMKEKGLDFEEALKEAQQKGYAEADPTDDVEGFDAARKLAILCTLAFNKFILPEKIYTKGIKSISKSDIKYAEELGY
HVKLIAYAKIDENERLEAWVHPVMIKKDNPLSSVNGVFNAILVDGNAVGEVMFYGQGAGMMPTASAVVADIMDVKNHIVI
QNGCEDADLLPVVDTASKYYIRLIAIDKPGVMSKITGILGDKGISLLSVVQKGVLKDTAEIVLITHIANTGKVFEALDEI
QNMKEVESIESVIRVEEE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB0868_00309 YP_008211635.1 Homoserine dehydrogenase Not tested AbaR26 Protein 3e-57 48
BJAB07104_00305 YP_008207770.1 Homoserine dehydrogenase Not tested AbaR25 Protein 3e-57 48