Gene Information

Name : Thit_1629 (Thit_1629)
Accession : YP_003477442.1
Strain : Thermoanaerobacter italicus Ab9
Genome accession: NC_013921
Putative virulence/resistance : Virulence
Product : pyruvate kinase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0469
EC number : -
Position : 1641623 - 1643374 bp
Length : 1752 bp
Strand : -
Note : KEGG: tex:Teth514_1195 pyruvate kinase., pyruvate, water dikinase; TIGRFAM: pyruvate kinase; PFAM: pyruvate kinase barrel; pyruvate kinase alpha/beta; PEP-utilising protein mobile region

DNA sequence :
ATGCGCAGAACAAAAATAGTATGTACAATAGGACCTGCCAGCGAAGACTATAATATACTGAGAAAATTAATTGAGAAAGG
CATGAACGTTGCACGACTTAATTTTTCTCATGGAGATTTTGCAGAACATGGAGCGAGAATTGACAATATAAAAAAAATAA
GGCAAGAGGTGGGGTTGCCTGTTGCTATTTTATTAGACACAAAAGGTCCTGAGATAAGAACAGGAAAGTTTAAAAATGGC
GAAGTACAATTAAAAGAAGGACAAACTTTTGTCATTACGACAAGAGATGTATTAGGAGACGAAACTATATGCAGTGTATC
CTACAAAGGGTTGCCTCAAGATGTGGAAAGAGGCAGCCGCATATTAATTGACGATGGGTTAATTTCTTTGAAGGTTACAG
ATGTTAAAGGAGAAGATATAGTTTGTATTGTAGAAAATTCTGGTCCTGTAAAAGATCATAAAGGAGTAAATGTTCCAGGG
GTAAAACTCAATCTTCCTGCATTAACTCAAAAAGACATAGACGATATAGAGTTTGGAATTCAAAAAGGCATTGATATGAT
TGCTGCTTCTTTTGTTAGAAAGGCTTCTGATGTTTTGGCAATAAGAAGACTTTTAGAAGAGAATAAGGCAGAGCATATTT
TAATTATTGCCAAAATAGAGAATCGCGAAGGAGTAGAAAATATAGACGAAATTATAAAGGTTTCAGATGGAATAATGGTA
GCCAGAGGAGACTTAGGGGTTGAGATTCCTCTTGAAGAAATACCAATCGTTCAAAAGATGATTATACAAAAATGCAATAA
AGCTGGGAAACCGGTAATTACTGCAACTCAAATGTTGGACTCTATGATGAGAAATCCAAGGCCTACAAGAGCAGAAGTTA
CAGATGTAGCAAATGCTATTCTTGATGGAACAGATGCTATAATGTTATCAGGGGAGACAGCCCAAGGTAAATACCCAATA
GAGGCCTTTGAGACAATGGCTAAGATTGCAGAAAAGACAGAAGCCTACGTGGGATACAAAGATATAATCGATAGAAATAT
TGATACAAATGTTTCTATTACAAACGCTATAAGCCATGCAACTTGTACTACAGCGAGAGATATAGGTGCAGCTGCTATAA
TAACTTGTACTAAATCTGGCTATACAGCAAGAATGGTGTCAAGGTACAGACCTCAAGCTCCGATTATTGCTACTACTCCA
AGCGAAAATGTTGCAAGGAAACTCTCTATAGTATGGGGCGTATATCCTTTAGTTACAGAAGAGGTTTCTACTACAGATGA
AATGATAGATGTGGCAATACAAAGTGCATTAACTGCAGGATTTATAAGGAATGGCGATATCGTAGTAATTTCCGCAGGAA
TTCCTGTAGCTATGGCAGGTACCACCAACATGTTGAAAGTACATATAGTAGGGGATGTTTTATTAAGAGGAATAGGTATA
GGTTCTAAAGCTACTACAGGTGCTGTATGTGTTATTAATGATATAAGTAAAGATAAAGATAAGTTCCGAGAAGGAGATAT
AATAGTTGCTGCAAAGACTGAAAGAGATTTTATGCCTCTTATAGAAAAAGCTTCGGCTATAATCACAGAAGAAGGAGGGC
TTACTTCTCACGCTGCTATTGTGGGGCTAAACCTAGGAATCCCTGTAATTGTAGGGTGCGAAGGAGCAACTTCTAAACTC
AAAGATGGCATGACTGTAACGGTTGACACCGTTAGAGGATTTGTGTATAAAGGAACTGTAAATATTAAATAA

Protein sequence :
MRRTKIVCTIGPASEDYNILRKLIEKGMNVARLNFSHGDFAEHGARIDNIKKIRQEVGLPVAILLDTKGPEIRTGKFKNG
EVQLKEGQTFVITTRDVLGDETICSVSYKGLPQDVERGSRILIDDGLISLKVTDVKGEDIVCIVENSGPVKDHKGVNVPG
VKLNLPALTQKDIDDIEFGIQKGIDMIAASFVRKASDVLAIRRLLEENKAEHILIIAKIENREGVENIDEIIKVSDGIMV
ARGDLGVEIPLEEIPIVQKMIIQKCNKAGKPVITATQMLDSMMRNPRPTRAEVTDVANAILDGTDAIMLSGETAQGKYPI
EAFETMAKIAEKTEAYVGYKDIIDRNIDTNVSITNAISHATCTTARDIGAAAIITCTKSGYTARMVSRYRPQAPIIATTP
SENVARKLSIVWGVYPLVTEEVSTTDEMIDVAIQSALTAGFIRNGDIVVISAGIPVAMAGTTNMLKVHIVGDVLLRGIGI
GSKATTGAVCVINDISKDKDKFREGDIIVAAKTERDFMPLIEKASAIITEEGGLTSHAAIVGLNLGIPVIVGCEGATSKL
KDGMTVTVDTVRGFVYKGTVNIK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
STY1744 NP_456147.1 pyruvate kinase Not tested SPI-2 Protein 3e-106 51
pykF YP_216386.1 pyruvate kinase Not tested SPI-2 Protein 2e-106 51
pykF NP_805051.1 pyruvate kinase Not tested SPI-2 Protein 2e-106 51
pykF CAA68205.1 pyruvate kinase like protein Not tested SPI-2 Protein 8e-106 51

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Thit_1629 YP_003477442.1 pyruvate kinase VFG0479 Protein 7e-107 51