Gene Information

Name : Thit_1421 (Thit_1421)
Accession : YP_003477241.1
Strain : Thermoanaerobacter italicus Ab9
Genome accession: NC_013921
Putative virulence/resistance : Resistance
Product : cystathionine gamma-synthase
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0626
EC number : 2.5.1.48
Position : 1438149 - 1439330 bp
Length : 1182 bp
Strand : +
Note : KEGG: tpd:Teth39_0897 cystathionine gamma-synthase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein

DNA sequence : 
ATGGATTTAAGTTTTAAAACAAAAGTAGTACATACTGGAAACTACATAAATAAAGAAATTCCTCCAATGCCAAAAACTCT
TCCTATCTATCAAACTTCTGTTTTCACTTTTGATACGCTGGAAGAAGTTTACGATTATCTTGGTGGTAATCCTTCAAGGT
ATATGTACACAAGACTTGGAAACCCTAATCAAACAGCAGTAGAAGAATTAATTGCCAGTTTAGAAGGTGCAGAAGCAGGA
CAGTCTTGTTCATCCGGAATGGCGGCAATTTCTTCAGCTTTGTTGGCAGAAGTAAATTCAGGAGACCACATAATCGCCGC
AAAAGATATTTACGGTGGTACAAACAGTCTTTTTAATGCAGAATTTAAAAGACTTAATATTGATGTAACTTTAGTGGATT
TCTCCGATTTAGAAGCTGTTGAAAAAGCTATAAAACCAAACACTAAAGTGATATACATGGAAATCATGACAAATCCTCTA
ATAAGAGTTTTTGACGTAGTAGAAGTTGCAAATATCGCAAAAAAGCACAATATAAAATTGTTTGTTGACAATACTTTCAC
AACCCCTTATTTGATAAAACCAATTAAATTAGGAGCCTATGCTGTAATACACAGTGCAACAAAATACATTAACGGCCACA
GCGATGTCATTGCCGGACTTATAGCAGGCAATAAAGAATTTATCTCACGTACAAAAAGAATTACGCAAAACTTTGGCGGT
TCAATGAGCCCCTTTGATGCATGGCTGACCTTAAGAGGAGCAAAAACTCTATTCTTAAGAATGAGAGAACACTGTAAAAA
TGCAATGGAACTGGCTAAATTTTTAGAAAGTCATTCCAAAGTCAAAAAAGTATATTATCCTGGACTTCCTTCTCATCCCG
ACTACAGTGTTTCAAAGAAGCTGTTTAAAGATGAGTTTGGAGGTATGTTAAGTTTTGAAATAGAAGGTGGAGAACCTGAA
GTAGATAAGTTTATGCAAGGACTTAAACTTGTTAAATTTGCTCCTTCACTGGCAGGAGTACAAACTATGATAACTCATCC
AAAATCCACGTCCCATAGGTCTCTCAGCAAGGAAGAATTAAACGCGTTAGGAATTTCAGAAGGGCTTATAAGAGTTTCTG
TTGGAATAGAGGAGATAGAGGATATTATAAAAGACTTTAAACAAGCTCTTGACAAGATATAA

Protein sequence : 
MDLSFKTKVVHTGNYINKEIPPMPKTLPIYQTSVFTFDTLEEVYDYLGGNPSRYMYTRLGNPNQTAVEELIASLEGAEAG
QSCSSGMAAISSALLAEVNSGDHIIAAKDIYGGTNSLFNAEFKRLNIDVTLVDFSDLEAVEKAIKPNTKVIYMEIMTNPL
IRVFDVVEVANIAKKHNIKLFVDNTFTTPYLIKPIKLGAYAVIHSATKYINGHSDVIAGLIAGNKEFISRTKRITQNFGG
SMSPFDAWLTLRGAKTLFLRMREHCKNAMELAKFLESHSKVKKVYYPGLPSHPDYSVSKKLFKDEFGGMLSFEIEGGEPE
VDKFMQGLKLVKFAPSLAGVQTMITHPKSTSHRSLSKEELNALGISEGLIRVSVGIEEIEDIIKDFKQALDKI

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
metB YP_281510.1 cystathionine beta-lyase Not tested Not named Protein 1e-54 42

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Thit_1421 YP_003477241.1 cystathionine gamma-synthase BAC0207 Protein 3e-62 41