Gene Information

Name : Thit_1232 (Thit_1232)
Accession : YP_003477058.1
Strain : Thermoanaerobacter italicus Ab9
Genome accession: NC_013921
Putative virulence/resistance : Virulence
Product : flagellar protein export ATPase FliI
Function : -
COG functional category : N : Cell motility
COG ID : COG1157
EC number : 3.6.3.14
Position : 1260462 - 1261775 bp
Length : 1314 bp
Strand : -
Note : SMART: ATPase AAA; TIGRFAM: flagellar protein export ATPase FliI; ATPase, FliI/YscN family; KEGG: tpd:Teth39_1254 flagellar protein export ATPase FliI; PFAM: H+transporting two-sector ATPase alpha/subunit beta central region; H+transporting two-sector ATP

DNA sequence :
ATGAGTGAGATTATTTTCACTAAATATAAAAGAGCTCTTCAAGAAAAAAGATTAATTCAATACTATGGAAAAGTTTCTCA
AGTAATAGGATTGACAATCGAAAGTACAGGGCCTCTTTCCAATATAGGAGAGATATGTAATATCAAGACTACCAATGGAA
ATATAATCTCAGCAGAAGTTGTGGGCTTTAAAGAAGAAAAAGTGTATCTCATGCCTTTAGGAAATATGGAGGGAATAGGA
GCAGGCAGCAAAGTTATAGCTACAGGTCAAACCCTAAGGGTTAGCGTAGGGAAGGAGCTTCTTGGGAGGATATTAGATGG
TTTGGGCAATCCTATAGATAGTAAAGGACCAGTTAAATTTGAAAAATCTATTCCTATCAATAATGTACCACCTGACCCTT
TAGAAAGGAAGAGAATTAGAGAGGTTATGCCTCTTGGAATAAAAGCGATAGATGGACTTCTTACCTGCGGCAAAGGGCAG
AGAATTGGTATCTTTGCGGGGAGCGGTGTAGGGAAAAGTACATTGCTAGGCATGATGGCAAGAAACGCCAAAGCTGATTT
AAATGTGATAGCTCTTATAGGCGAAAGAGGAAGAGAGGTAAATGAATTTTTGGAAAAAGATCTAGGAGAAGAAGGTTTAA
AAAAATCTGTAGTTGTAGTAGCTACCTCTGATACTCCAGCACTTATACGAGTAAAAGGTGCTATGACTGCCACTGCTATA
GCTGAATATTTTAGAGATCAAGGATTAGATGTCCTTTTGATGATGGATTCAGTAACTCGCTTTGCCATGGCTCAAAGAGA
AGTAGGCTTGTCTATAGGTGAAGCTCCTGTTTCACGAGGTTATACTCCTTCTGTTTTTTCAGTTTTGCCTAAGCTTTTGG
AACGCTCTGGATGCTCTAAAAAAGGTTCTATTACAGCCCTTTATACAGTATTGGTGGATGGAGACGACTTAAATGAACCA
ATTGCTGATGCAGTAAGGGGTATACTTGATGGACACATAGTTTTGTCTCGAAAACTTGCCAATAAGAATCACTATCCTGC
TATTGATGTATTAGCAAGTGTTAGCAGGGTGATGAATGACATAATTACAGAAGAACACAAAGAATTAATAGCGAGATTTA
AAGATATTTTGGCATCTTACACAGAAGCGGAAGATTTAATAAACATAGGGGCATATAATTTTGGCAGCAATCCTAAAATT
GACGAGGCCATTGAGTTAAACGACAAAATGAACAATTTCTTAAGGCAGAGAATAGACGAATCCTATGACTTTGAAACTAC
AAAACAACTGCTATATGAATCTATTAAAAGGTGA

Protein sequence :
MSEIIFTKYKRALQEKRLIQYYGKVSQVIGLTIESTGPLSNIGEICNIKTTNGNIISAEVVGFKEEKVYLMPLGNMEGIG
AGSKVIATGQTLRVSVGKELLGRILDGLGNPIDSKGPVKFEKSIPINNVPPDPLERKRIREVMPLGIKAIDGLLTCGKGQ
RIGIFAGSGVGKSTLLGMMARNAKADLNVIALIGERGREVNEFLEKDLGEEGLKKSVVVVATSDTPALIRVKGAMTATAI
AEYFRDQGLDVLLMMDSVTRFAMAQREVGLSIGEAPVSRGYTPSVFSVLPKLLERSGCSKKGSITALYTVLVDGDDLNEP
IADAVRGILDGHIVLSRKLANKNHYPAIDVLASVSRVMNDIITEEHKELIARFKDILASYTEAEDLINIGAYNFGSNPKI
DEAIELNDKMNNFLRQRIDESYDFETTKQLLYESIKR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
lscN AAO18044.1 LscN Virulence TTSS locus Protein 8e-108 55
hrcN YP_362163.1 type III secretion system ATPase Virulence Hrp PAI Protein 6e-105 53
hrcN YP_198730.1 type III secretion system ATPase Virulence Hrp PAI Protein 3e-105 53
hrpB6 AAB08461.1 HrpB6 Virulence Hrp PAI Protein 4e-105 53
hrpB6 BAB07852.1 HrpB6 Virulence Hrp PAI Protein 2e-105 53
hrpB6 AAF61281.1 HrpB6 Virulence Hrp PAI Protein 2e-105 53
hrcN NP_640767.1 type III secretion system ATPase Virulence Hrp PAI Protein 2e-104 52
hrcN AAP34339.1 HrcN Virulence Hrp PAI Protein 3e-105 51
escN AAL57542.1 EscN Virulence LEE Protein 2e-92 51
escN AAC38383.1 EscN Virulence LEE Protein 2e-92 51
escN NP_290268.1 hypothetical protein Virulence LEE Protein 3e-92 51
escN CAC81862.1 EscN protein Virulence LEE II Protein 1e-92 51
ECs4568 NP_312595.1 EscN Virulence LEE Protein 3e-92 51
escN CAI43874.1 EscN protein Virulence LEE Protein 7e-93 51
escN YP_003232153.1 T3SS structure protein EscN Virulence LEE Protein 2e-92 51
escN YP_003223475.1 translocator EscN Virulence LEE Protein 9e-93 51
escN AAC31513.1 L0034 Virulence LEE Protein 2e-92 51
escN YP_003236088.1 translocator EscN Virulence LEE Protein 8e-93 51
unnamed ACU09458.1 type III secretion apparatus H+-transporting two-sector ATPase Virulence LEE Protein 2e-92 51
escN AAK26715.1 EscN Virulence LEE Protein 2e-92 51
escN AFO66300.1 putative LEE-encoded type III secretion system ATPase Virulence SESS LEE Protein 5e-89 51
escN AFO66415.1 putative LEE-encoded type III secretion system ATPase Virulence SESS LEE Protein 5e-89 51
hrcN NP_636610.1 type III secretion system ATPase Virulence Hrp PAI Protein 3e-102 51
XC_3006 YP_244074.1 type III secretion system ATPase Virulence Hrp PAI Protein 3e-102 51
unnamed AAL06369.1 EscN Virulence LEE Protein 2e-90 50
YPO0267 YP_002345348.1 type III secretion system ATPase Virulence Not named Protein 5e-93 50
ssaN YP_216423.1 type III secretion system ATPase Virulence SPI-2 Protein 1e-85 49
ssaN NP_456113.1 putative type III secretion ATP synthase Virulence SPI-2 Protein 2e-84 49
ssaN NP_805086.1 type III secretion system ATPase Virulence SPI-2 Protein 2e-84 49
ssaN CAA70537.1 secretion system apparatus Virulence SPI-2 Protein 1e-85 49
ssaN NP_460380.1 type III secretion system ATPase Virulence SPI-2 Protein 1e-85 49
hrcN AAG33879.1 HrcN Virulence Hrp PAI Protein 4e-79 46
hrcN NP_791227.1 type III secretion cytoplasmic ATPase HrcN Virulence Hrp PAI Protein 1e-81 46
hrcN AAR25633.1 type III secretion cytoplasmic ATPase HrcN Not tested Not named Protein 4e-78 46
hrcN AAB06001.1 HrcN Virulence Hrp PAI Protein 3e-91 46
hrcN AAT96195.1 HrcN Virulence T-PAI Protein 7e-83 45
hrcN AAT96141.1 HrcN Virulence T-PAI Protein 7e-83 45
hrpJ4 AAA81942.1 HrpJ4 Virulence Hrp PAI Protein 4e-78 44
hrcN ABQ88354.1 HrcN Virulence Hrp PAI Protein 4e-78 44
hrcN AAT96258.1 HrcN Virulence S-PAI Protein 6e-81 44
hrcN AAT96299.1 HrcN Virulence S-PAI Protein 2e-81 44
hrcN AAT96339.1 HrcN Virulence S-PAI Protein 2e-81 44
hrcN ABA47275.1 HrcN Virulence S-PAI Protein 7e-87 44
invC AAS66861.1 InvC Not tested SSR-2 Protein 2e-76 43
ysaN AAS66842.1 YsaN Not tested SSR-1 Protein 2e-74 42
invC YP_217813.1 ATP synthase SpaL Virulence SPI-1 Protein 9e-74 42
spaI NP_457288.1 secretory apparatus ATP synthase (associated with virulence) Virulence SPI-1 Protein 9e-74 42
spaI NP_806497.1 ATP synthase SpaL Virulence SPI-1 Protein 9e-74 42
invC NP_461815.1 ATP synthase SpaL Virulence SPI-1 Protein 9e-74 42
ECs3730 NP_311757.1 ATP synthase SpaL Not tested LIM Protein 2e-72 42

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Thit_1232 YP_003477058.1 flagellar protein export ATPase FliI VFG2144 Protein 6e-113 56
Thit_1232 YP_003477058.1 flagellar protein export ATPase FliI VFG0048 Protein 8e-110 55
Thit_1232 YP_003477058.1 flagellar protein export ATPase FliI VFG0390 Protein 3e-107 54
Thit_1232 YP_003477058.1 flagellar protein export ATPase FliI VFG0192 Protein 8e-110 53
Thit_1232 YP_003477058.1 flagellar protein export ATPase FliI VFG0812 Protein 1e-92 51
Thit_1232 YP_003477058.1 flagellar protein export ATPase FliI VFG0730 Protein 9e-93 51
Thit_1232 YP_003477058.1 flagellar protein export ATPase FliI VFG1254 Protein 9e-104 50
Thit_1232 YP_003477058.1 flagellar protein export ATPase FliI VFG0515 Protein 6e-86 49
Thit_1232 YP_003477058.1 flagellar protein export ATPase FliI VFG2331 Protein 8e-94 48
Thit_1232 YP_003477058.1 flagellar protein export ATPase FliI VFG2499 Protein 3e-97 48
Thit_1232 YP_003477058.1 flagellar protein export ATPase FliI VFG1778 Protein 5e-73 44
Thit_1232 YP_003477058.1 flagellar protein export ATPase FliI VFG1008 Protein 5e-73 43
Thit_1232 YP_003477058.1 flagellar protein export ATPase FliI VFG2459 Protein 4e-81 42
Thit_1232 YP_003477058.1 flagellar protein export ATPase FliI VFG0555 Protein 4e-74 42