Gene Information

Name : guaA (HMPREF0868_1066)
Accession : YP_003475359.1
Strain : Clostridiales genomosp. UPII9-5
Genome accession: NC_013895
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : 6.3.5.2
Position : 692298 - 693875 bp
Length : 1578 bp
Strand : +
Note : identified by match to protein family HMM PF00117; match to protein family HMM PF00958; match to protein family HMM PF06508; match to protein family HMM TIGR00884; match to protein family HMM TIGR00888

DNA sequence :
ATGAGTAAACAGATTTTAAACTTGGATTTGAGCCATGCTGGACTGATAGACGAAAAAATAGCTGTGCTGGATTTCGGCGG
ACAGTATAAACAATTGATCGCACGTCGCGTCAGAGAAGCCGGGGTTTACTGCGAAATTTTGCCGGCAGAGACCTCAGCCG
CGACAATTGTTGCCGGAGGATATTGCGGTGTGATTTTAAGCGGGGGTCCGAACTCCGTCTATGATGAAGCCGGGATAAGC
GCTGACATGGGTATCATTACTTTAGGCATACCGCTGCTGGGAATTTGCTATGGAGCTCAGTGGTTGGCTCATATTATGGG
CGGCAAAGTGGTGGCGGCCGGCAAAGGTGAATACGGCAAACGTGAAGTTCAAGTTAAAGACAACGGCACGTTATTGGCTT
CTGTCGCCTCGACGACACAAGTTTGGATGAGCCATCGTGACCAAATAATTTCCCTGCCGAACGGCTTCACTGTGTTGGCG
GCCTCAGAAACTTGCCCGATTGCAGCTTATGCCGACGAAAAACGCAAAATTTATGGCATCCAGTTTCATCCTGAAGTCGA
ACATACCTTAGAAGGCAGAACAATGTTGGACAATTTTATTTATAAAGTTTGCCGCGCGAAAGGCAGCTGGTCGATGAATG
ATTTTGCTGGTGCCATGGTTAAAAAATTGTGTGAGGCGATAGGATCGGCAAAAGTGATTTGTGCATTCAGTGGCGGAGTT
GATTCAGCGGTTGCGGCCTTGCTTGTTCATAAAGCCATCGGTAACAATCTGACGTGCATTTTCGTTGATCATGGCTTGCT
ACGCTTGGGCGAGTCGGAGCAGGTTATGGAAGTTTTTGGGAAAAATTACAATATGAATATTCGGCGTATTGATGCCAAAC
AACAGTTTTTGACTGCTTTGCAAGGTGTTGCCGACCCGGAGAAAAAACGTAAAATTATTGGCGCCGAATTTATTAAAGTA
TTTGAAAGAATTGCTGACGAATATCACAATGTTGATTATTTGGTACAGGGAACGATTTATCCGGACGTTATCGAAAGTGG
TACGGATAAGGCGGCCGTAATCAAAAGCCATCACAACGTCGGAGGCCTGCCGGATAAGATTAATTTTAAAGCGATTATAG
AGCCGTTGCGAAATCTTTTCAAAGACGAAGTACGAAAAGTCGGCATGACTTTGGGGATGCCGGAAGAATTGGCTTGGCGT
CAACCATTCCCCGGACCGGGCTTGGCGGTTCGTGTTTTGGGTGAAATTACCGAAGCCAAGTTGAATATTTTGCGCGCCGC
CGACGCTATTTTCCGTGAGGAAATTTTCAATTTCGGTCTGCACCGGCAAATTTCGCAGTACTTTGCCGTCCTCACACCAC
TTAAATCAGTGGGCGTCATGGGTGATGCACGGACTTATGACTATATTGCAGCTTTACGCGCCATCATAACTAATGATTTC
ATGACAGGGGAGTGGGCAAAACTGCCATGGGAGTTGCTCGAAAAGGTGAGTTACCGTATCGTAAATGAGGTCAAAGGGAT
TAATCGGGTTGTGTATGATGTTACAGGCAAACCGCCAGCGACGATCGAATGGGAATAA

Protein sequence :
MSKQILNLDLSHAGLIDEKIAVLDFGGQYKQLIARRVREAGVYCEILPAETSAATIVAGGYCGVILSGGPNSVYDEAGIS
ADMGIITLGIPLLGICYGAQWLAHIMGGKVVAAGKGEYGKREVQVKDNGTLLASVASTTQVWMSHRDQIISLPNGFTVLA
ASETCPIAAYADEKRKIYGIQFHPEVEHTLEGRTMLDNFIYKVCRAKGSWSMNDFAGAMVKKLCEAIGSAKVICAFSGGV
DSAVAALLVHKAIGNNLTCIFVDHGLLRLGESEQVMEVFGKNYNMNIRRIDAKQQFLTALQGVADPEKKRKIIGAEFIKV
FERIADEYHNVDYLVQGTIYPDVIESGTDKAAVIKSHHNVGGLPDKINFKAIIEPLRNLFKDEVRKVGMTLGMPEELAWR
QPFPGPGLAVRVLGEITEAKLNILRAADAIFREEIFNFGLHRQISQYFAVLTPLKSVGVMGDARTYDYIAALRAIITNDF
MTGEWAKLPWELLEKVSYRIVNEVKGINRVVYDVTGKPPATIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 9e-138 57
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 9e-138 57
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 1e-137 56
guaA NP_938969.1 GMP synthase Not tested Not named Protein 4e-119 49