Gene Information

Name : HMPREF0868_0489 (HMPREF0868_0489)
Accession : YP_003474820.1
Strain : Clostridiales genomosp. UPII9-5
Genome accession: NC_013895
Putative virulence/resistance : Unknown
Product : putative type I restriction-modification system, M subunit
Function : -
COG functional category : V : Defense mechanisms
COG ID : COG0286
EC number : -
Position : 1325234 - 1326739 bp
Length : 1506 bp
Strand : -
Note : identified by match to protein family HMM PF02384

DNA sequence :
ATGGCAGATAAATCAAAAGCTACTCTTGGTTTTGAGAAGCAAATCTGGGATGCGGCATGCGTGCTGTGGGGGCACATTCC
GGCATCAGAATATAGAAACGTAATTATCGGGCTTATTTTCTTGAAGTACATTTCTACGGCATTTGACAAGAAATATCAAC
AGCTTATTGCTGAAGGAGATGGATTTGAGAATGATCCTGATGCATATCTTGAAGATAACGTATTCTTCGTACCGGAGGAT
GCCCGTTGGGAAAAGATTGCCAAAGCAGCACATGAGCCGGAAATTGGAAAAGTTATTGATGAAGCCATGCGTGCAATCGA
GGCTGATAATAAAAAACTCAAAAACGTACTTCCAAAGAATTATGCCAGTCCGGATCTTGATAAGAAAATCCTCGGCAATG
TCGTTGACCTCTTTACAAACATGGATATGAGCGATACGGAAGGCAACCGTGATGTTCTCGGCAGAACCTACGAATACTGC
ATCGCTCAATTCGCCGAAAAAGAAGGCAAAGGTGGCGGTGAATTCTATACGCCGTCAAGCATCGTAAATACACTAGTGGC
AATTTTAAAGCCTTATGCAAATTGTCGCGTATATGATTGCTGCTGTGGCAGTGGCGGCATGTTCGTACAGAGTGCAAAGT
TCATTCAGGCACACTCCGGTAACCGAGGCTCAATTTCAATTTATGGTCAGGAAGCTAATCCGGATACATGGAAGATGGCA
ATCATGAATCTTACGATTCGCGGGCTTGATGCAGACCTTGGTGCTTATCATGCAGACACATTTACAAATGACCTTCATCC
AACATTGAAAGCAGACTTCATTCTCGCCAACCCTCCCTTCAACTACAATCCGTGGGGACAGGAAGATCTGAAGGACGACG
TTCGCTGGAAATACGGTGTACCTCCTGCAAGCAATGCCAACTATGCATGGATTCAACATATGATTCATCATCTTGCCCCG
AGCGGAAAAATCGGGCTAGTTCTTGCAAACGGAGCATTGTCTTCCCAGAATGGTGGCGAGGGCGAGATCAGAAAGAAAAT
CATTGAAGATGACTTAATCGAAGGTATCATCGCTATGCCTCCCCAACTCTTCTATAGCGTAACTATCCCCGCGACGCTTT
GGTTCATTACAAAGGGCAAGAAACAAAAAGGCAAAACAGTTTTTATCGATGCACGAAAAATGGGACACATGGTAGACCGT
AAGCATCGAGACTTTACCGAAGAAGATATCCAAAAGCTCGCAGATACAATTGAGGCTTTCCAGAACGGCACGCTTGAAGA
TGAAAAAGGTTTCTGCTCTGTAGCGACGATTCAGGATATAGCAAAGCAGGATTACGTTTTGACTCCGGGACGCTATGTTG
GTATTGAAGAGCAGGAAGATGATGGTGAACCGTTTGATGAGAAAATGACCAGACTGACATCAGAACTTTCTGACATGTTC
GAACGCTCTCATGAGCTTGAAGACGAGATTCGTAAGAAGTTGGGGGCAATTGGATATGAAATATAA

Protein sequence :
MADKSKATLGFEKQIWDAACVLWGHIPASEYRNVIIGLIFLKYISTAFDKKYQQLIAEGDGFENDPDAYLEDNVFFVPED
ARWEKIAKAAHEPEIGKVIDEAMRAIEADNKKLKNVLPKNYASPDLDKKILGNVVDLFTNMDMSDTEGNRDVLGRTYEYC
IAQFAEKEGKGGGEFYTPSSIVNTLVAILKPYANCRVYDCCCGSGGMFVQSAKFIQAHSGNRGSISIYGQEANPDTWKMA
IMNLTIRGLDADLGAYHADTFTNDLHPTLKADFILANPPFNYNPWGQEDLKDDVRWKYGVPPASNANYAWIQHMIHHLAP
SGKIGLVLANGALSSQNGGEGEIRKKIIEDDLIEGIIAMPPQLFYSVTIPATLWFITKGKKQKGKTVFIDARKMGHMVDR
KHRDFTEEDIQKLADTIEAFQNGTLEDEKGFCSVATIQDIAKQDYVLTPGRYVGIEEQEDDGEPFDEKMTRLTSELSDMF
ERSHELEDEIRKKLGAIGYEI

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
hsdM BAD24842.1 HsdM protein Not tested Type-V SCCmec Protein 8e-137 56
hsdM YP_251979.1 type I restriction-modification system DNA methylase Not tested SCCmec Protein 1e-137 56
hsdM BAH57701.1 type I restriction-modification system DNA methylase Not tested Type-VII SCCmec Protein 3e-138 56
api49 CAF28523.1 putative HsdM-like N-methyl transferase Not tested YAPI Protein 1e-102 45