Gene Information

Name : Thal_0722 (Thal_0722)
Accession : YP_003473482.1
Strain : Thermocrinis albus DSM 14484
Genome accession: NC_013894
Putative virulence/resistance : Virulence
Product : urease subunit alpha
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0804
EC number : -
Position : 688897 - 690600 bp
Length : 1704 bp
Strand : +
Note : KEGG: ttu:TERTU_4206 urease, subunit alpha; TIGRFAM: urease, subunit alpha; PFAM: amidohydrolase; Urease alpha-subunit domain protein

DNA sequence :
ATGAGGATATCTAAACAATCTTATGCCAGACTTTATGGTCCAACAAAAGGTGACAGAATAAGGTTAGGTGATACAAATTT
GATAATAGAAGTTGAGGAAGATTTCAATTTGTACGGTGAGGAAGTTTGTTTTGGTGGAGGGAAAGTTATAAGGGATGGTA
TGGGTCAATGTCAACTTTCGCGAAAGGATGGTACTCCTGATTTAGTTATAGTAGGTGCTGTAATCGTAGATTATTGGGGC
ATAGTAAAGGCTGATGTAGGAATAAGAGATGGAAAGATAGTTGCCATAGGTAAAGCTGGAAATCCAAATATTCAAGATGG
TGTGACCCCTGGCTTGGAAATAGGTCCATGTACGGAAGTTATTGATGCACGAGGGAAAATACTAACAGCAGGGGGTATTG
ATTGCCATGTACATTTTATATGTCCTCAACAAATATGGGAAGCTCTTTATAGTGGTATAACCACAATGATTGGTGGAGGC
ACAGGACCTACAGAAGGTACCAAGGCAACCACATGTACACCAGGACCGTGGAACATAATACATATGCTAAAGGCTTTAGA
AGCTTTTCCAATGAACTTTGGACTTCTCGGGAAAGGAAATTCATCTTTACCTTCCCCCCTTATAGAGCAAATAGAAGCTG
GGGCAATGGGATTAAAAATTCACGAAGATTGGGGGGCAACTCCAGCGGTTATAGATTGCGCTCTTACGGTGGCGGATGAA
TACGATATACAAATAGCGATACATACTGATACTTTAAATGAGTGTGGTTATGTTGAAGATACGATCAAGGCCTTTAAAGG
AAGAACCATTCATACATATCATTCAGAAGGTGCAGGCGGAGGACATGCACCCGATATAATGAAAGTGGTTTCTCATATAA
ATGTTTTGCCTTCTAGTACTAACCCTACTATGCCGTATACCGTAAACACATTTGATGAGCATTTTGATATGTTAATGGTG
TGTCATCACCTATCTCCAAATATACCAGAGGACGTAGCTTTTGCGGAATCCAGAATAAGACCAGAAACAATGGCTGCGGA
GGATGTACTTCACGATATAGGGGCTATTTCTATGATGTCCAGTGATTCGCAGGCCATGGGGAGGGTAGGAGAGGTAATAA
TTAGAACATGGCAAACTGCCCATAAAATGAAGGAAGAAAGGGGTAAACTTCCGGAGGATTCGGATAGAAATGATAATTTC
AGAGTAAAGAGATATATCAGTAAATACACAATTAATCCAGCGATAGCCTTTGGTATAGCTGAGTACGTTGGTTCAGTAGA
GGTAGGGAAAATTGCTGACCTTGTTATATGGGATCCAAAATTCTTTGGCGTTAAACCCGACTTGGTAATAAAGGGTGGAA
TGGTGGTTGCGTCATTAATGGGAGATCCAAATGCTTCAATTCCTACACCTCAACCTGTACTTTACAGACCCATGTTTGCT
TCGTTTGGTAGTGCAGTTAACAAGGTTTCTGCATTCTTTGTTTCTCAAGTATCCTTAGAAAAAGGTTGGATAGATGATCT
AAAAAGACCATTACTTCCAGTAAGAAAAACAAGAGTAATATCAAAAAAAGACATGATATTAAATGATGCATTACCTAACA
TAAAGATAGATCCAGAAACCTACAAAGTTTACATCGATGGTGAACTTATAACGAGTAAGCCAGCCAAAAGCTTACCCCTA
ACTCAGCGATATTTCCTATTCTAG

Protein sequence :
MRISKQSYARLYGPTKGDRIRLGDTNLIIEVEEDFNLYGEEVCFGGGKVIRDGMGQCQLSRKDGTPDLVIVGAVIVDYWG
IVKADVGIRDGKIVAIGKAGNPNIQDGVTPGLEIGPCTEVIDARGKILTAGGIDCHVHFICPQQIWEALYSGITTMIGGG
TGPTEGTKATTCTPGPWNIIHMLKALEAFPMNFGLLGKGNSSLPSPLIEQIEAGAMGLKIHEDWGATPAVIDCALTVADE
YDIQIAIHTDTLNECGYVEDTIKAFKGRTIHTYHSEGAGGGHAPDIMKVVSHINVLPSSTNPTMPYTVNTFDEHFDMLMV
CHHLSPNIPEDVAFAESRIRPETMAAEDVLHDIGAISMMSSDSQAMGRVGEVIIRTWQTAHKMKEERGKLPEDSDRNDNF
RVKRYISKYTINPAIAFGIAEYVGSVEVGKIADLVIWDPKFFGVKPDLVIKGGMVVASLMGDPNASIPTPQPVLYRPMFA
SFGSAVNKVSAFFVSQVSLEKGWIDDLKRPLLPVRKTRVISKKDMILNDALPNIKIDPETYKVYIDGELITSKPAKSLPL
TQRYFLF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ureC NP_286680.1 urease subunit alpha Virulence TAI Protein 5e-166 66
ureC NP_287088.1 urease subunit alpha Not tested TAI Protein 5e-166 66
ureC YP_005684266.1 Urease alpha subunit Not tested PiCp 7 Protein 5e-154 60
ureC YP_005682174.1 Urease alpha subunit Not tested PiCp 7 Protein 9e-154 60
ureC YP_003784325.1 urease subunit alpha Not tested PiCp 7 Protein 9e-154 60
ureC YP_005686358.1 Urease alpha subunit Not tested PiCp 7 Protein 9e-154 60

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Thal_0722 YP_003473482.1 urease subunit alpha VFG0270 Protein 2e-155 62