Gene Information

Name : Thal_0299 (Thal_0299)
Accession : YP_003473061.1
Strain : Thermocrinis albus DSM 14484
Genome accession: NC_013894
Putative virulence/resistance : Virulence
Product : nucleotide sugar dehydrogenase
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG0677
EC number : -
Position : 298263 - 299576 bp
Length : 1314 bp
Strand : +
Note : KEGG: dvl:Dvul_0210 UDP-glucose/GDP-mannose dehydrogenase; TIGRFAM: nucleotide sugar dehydrogenase; PFAM: UDP-glucose/GDP-mannose dehydrogenase; UDP- glucose/GDP-mannose dehydrogenase dimerisation; UDP- glucose/GDP-mannose dehydrogenase

DNA sequence :
ATGGTTTCACTGGAGGATCTGGAAAAGGGAAAGGAGAGTATATGTGTGGTAGGCTTAGGATACGTAGGTTTACCTTTGGC
TGTAGCCCTCTCTAAGCATTTCCGTGTTTTCGGGTACGACAAAAACACCAAGAGGGTAGAGGAGCTTAAGGTGGGTATAG
ACTCCACAGGAGAGGTAGAAGCTGAGAAGTTAATAGGTACCAACGTTCAGTTTTCCTCAGATCCCTCCGTCATATCCCAA
TCCAGGTTTATAATAGTGGCTGTTCCCACACCTGTGGATAAACTTAAGAACCCGGATCTCTCCTTTATAAGATCTGCATC
CGCCTTGGTGGGTAGGTACATGAGGAGGGGAAGTGTGGTGGTTTACGAATCTACCGTCTATCCCGGTGCTACAGAAGAGG
TGTGCGTACCGATACTGGAAAGGGAGAGCGGTCTTGTGTGGAAGAGGGACTTCTTTGTGGGATACTCCCCGGAGAGAATA
AACCCGGGAGATCCTCATCACAGCTTGGAGAAAGTGGTAAAGGTGGTGTCTGCTGATACACCCCAGACGCTGCAGGTGGT
GAAAGGGGTTTACGAAAAGGTGGTGAAAGCTGGCGTGTATGTTGCTCCTGATATAAAGACTGCAGAAGCGGCCAAAGTGA
TAGAGAACATACAGCGAGACATCAACATAGCTCTCATAAACGAACTAGCCATAATATTTCACCGTCTTGGGCTGGATACA
AGGGAGGTTCTAAAAGCGGCCTCCACCAAGTGGAACTTTCTGAAGTTTGAACCTGGACTCGTGGGAGGACACTGTATACC
TGTGGATCCCTACTATCTGGCTCACAAATCTAAGGAGGTGGGATATATTCCGGAGCTTATTCTAGCAGGCAGAAGGGTTA
ACGAGCATATACCCGTGTTTGTGGCCCACCAAGTGGTAAAGACTTTAGTGAGAAGTGGAAAAAAGATTAAGGGAGCACGC
GTACTGGTACTGGGAGTCTCTTTCAAGGAGAATGTACCAGATGTAAGAAACTCTAAGGTTTACGACCTGGTAAAAGAACT
AGCCGACTTTGAGATGGAAACTTACATCTTTGATCCTATAGCGGACAGGGAAGGTTTGAAAGAAGAGTACGGCCTGGAGC
TGGTAGAAGACTACACAGTAGGAGCCCCCTACCATGCCGTGATTTTTGCGGTAAGACACAACATTTTTAAGGAAATATTT
TCCTTAGAACTCCTTAAAACTCTGTGCGATAAGCCCCCTATCCTAGTGGATATAAAAGGGATGTGGGACAAAGAGGAGGC
TCAAAAACTCGGCTTCGTGTATTGGAGGCTGTAG

Protein sequence :
MVSLEDLEKGKESICVVGLGYVGLPLAVALSKHFRVFGYDKNTKRVEELKVGIDSTGEVEAEKLIGTNVQFSSDPSVISQ
SRFIIVAVPTPVDKLKNPDLSFIRSASALVGRYMRRGSVVVYESTVYPGATEEVCVPILERESGLVWKRDFFVGYSPERI
NPGDPHHSLEKVVKVVSADTPQTLQVVKGVYEKVVKAGVYVAPDIKTAEAAKVIENIQRDINIALINELAIIFHRLGLDT
REVLKAASTKWNFLKFEPGLVGGHCIPVDPYYLAHKSKEVGYIPELILAGRRVNEHIPVFVAHQVVKTLVRSGKKIKGAR
VLVLGVSFKENVPDVRNSKVYDLVKELADFEMETYIFDPIADREGLKEEYGLELVEDYTVGAPYHAVIFAVRHNIFKEIF
SLELLKTLCDKPPILVDIKGMWDKEEAQKLGFVYWRL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
cap1L AAA64651.1 type 1 capsule synthesis gene Virulence SCCcap1 Protein 3e-94 52
tviB NP_807945.1 VI polysaccharide biosynthesis UDP-glucose/GDP-mannose dehydrogenase Virulence SPI-7 Protein 8e-90 52
tviB NP_458740.1 Vi polysaccharide biosynthesis protein, UDP-glucose/GDP-mannose dehydrogenase Virulence SPI-7 Protein 8e-90 52

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Thal_0299 YP_003473061.1 nucleotide sugar dehydrogenase VFG0431 Protein 3e-90 52