Gene Information

Name : SLGD_02364 (SLGD_02364)
Accession : YP_003472579.1
Strain : Staphylococcus lugdunensis HKU09-01
Genome accession: NC_013893
Putative virulence/resistance : Virulence
Product : ATP-dependent Clp protease, ATP-binding subunit ClpC/Negative regulator of genetic competence clcC/mecB
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0542
EC number : -
Position : 2433489 - 2435948 bp
Length : 2460 bp
Strand : -
Note : -

DNA sequence :
ATGTTATTTGGTAGATTAACTGAACGTGCGCAGCGTGTTTTAGCACATGCACAAGAAGAAGCTATTCGTTTGAACCACTC
AAATATTGGTACTGAACACTTGTTATTAGGTTTAATGAAGGAACCTGAAGGTATTGCTGCCAAAGTATTAGAAAGTTTTA
ATATTACTGAAGATAAAGTGATTACCGAAGTCGAAAAACTTATTGGCCACGGACAAGAACAAGCTGGGACGTTAAGATAT
ACACCTAGAGCTAAAAAAGTCATTGAATTATCAATGGATGAAGCTAGAAAACTTCATCACAATTTTGTTGGTACAGAACA
TATTTTATTAGGTTTAATTCGTGAAAATGAAGGTGTAGCGGCACGTGTTTTTGCAAATTTAGATTTAAATATTACGAAGG
CACGGGCTCAAGTTGTGAAAGCATTAGGTAGTCCAGAGATGGGTACGAAAAATGCACAAACAAATAAATCTAATAATACA
CCAACGTTAGATAGCTTAGCGCGTGACTTAACGGTGATTGCTAAAGATGGCACATTAGATCCGGTTATCGGTAGAACAAA
AGAGATTACACGTGTGATTGAAGTCTTGAGCCGTCGAACTAAAAATAATCCTGTGCTTATTGGTGAACCAGGTGTAGGTA
AAACAGCTATTGCTGAAGGTTTAGCACAAGCAATCATAAATAATGAAGTGCCAGAAACGTTAAAAGACAAACGTGTGATG
TCATTAGATATGGGTACGGTTGTAGCAGGTACGAAATATCGTGGTGAGTTTGAAGAACGCTTGAAAAAAGTAATGGAAGA
GATTCATCAAGCCGGCAACGTGATTCTATTTATTGACGAGTTACACACGCTCGTTGGTGCAGGTGGTGCAGAAGGGGCTA
TTGACGCTTCAAACATTTTAAAACCAGCACTTGCACGCGGCGAGTTACAATGCATTGGTGCAACTACTTTAGATGAATAT
CGTAAAAACATTGAAAAAGATGCCGCTTTAGAACGTCGTTTCCAACCGGTACAAGTTGATGAGCCGTCAGTTGAAGATAC
AATCGAAATTTTAAAAGGATTGCGTGATCGATACGAAGCACATCATCGTATTAACATTTCAGATCAAGCTTTAGATGCGG
CCGCAAAATTAAGTGACCGCTATGTTTCAGATCGCTTCTTGCCTGACAAAGCCATTGATTTAATTGATGAAGCAAGTTCT
AAAGTAAGATTAAGAAGTCACACAACACCAACAAATTTAAAATCAATTGAACAAGAAATTGAAACTGTAAAAAAAGAAAA
AGATGCTGCAGTTCACGCTCAAGAATTTGAAAATGCAGCCAACCTTAGAGACAAACAATCTAAATTAGAAAAGCAATATG
AAGATGCCAAAAAAGAATGGCAAAATGCGCAAGGTGGTAGTAACACAGAATTGTCGCAAGAAGATATTGCTGAAGTTATC
GCCGGTTGGACCGGAATTCCTTTAACAAAAATTAATGAAACAGAATCAGATCGACTATTAAATCTCGAAGCGACATTACA
TGGTCGTGTCATAGGTCAAAATGACGCTGTGACATCAATTAGTAAAGCTGTGCGTCGTGCACGTGCCGGCTTGAAGGATC
CTAAGCGTCCAATTGGTAGTTTCATTTTCTTAGGACCTACAGGGGTTGGTAAAACAGAATTAGCACGTGCATTAGCTGAA
ACAATGTTTGGTGAAGAAGATGCGATGATTCGTGTTGATATGAGTGAATTCATGGAAAAACATGCTGTGAGTCGCTTAGT
TGGGGCGCCTCCAGGATATGTAGGCCACGATGATGGTGGTCAATTAACTGAAAAAGTAAGACGCAAACCATATTCAGTTA
TTTTATTTGACGAAATCGAAAAAGCGCATCCAGATGTATTTAATATTTTACTTCAAGTATTAGATGATGGACATTTAACA
GATACGAAAGGACGTCGTGTAGATTTCCGCAATACTGTAATTATCATGACATCAAACGTTGGTGCCCAAGAGCTACAAGA
TCAACGATTTGCTGGATTTGGTGGTGCAAGCGAAGGTCAGGATTATGAGACAATTCGTAAAACAATGATGAAAGAGCTTA
AAAATGCTTTCCGTCCAGAGTTCTTAAACCGAGTGGATGATATTATTGTCTTCCATAAATTATCTAAAGACGAATTAAAA
GAAATTGTCACAATGATGGTTAATAAATTAACGCAACGTTTGTCAGAACAAGATATTCAAATTGAGGTAACAGACAAAGC
GAAAGAAGTTATTGCTGAAGAAGGTTATGATCCGGAATATGGTGCTCGTCCACTCATTCGTGCAATTCAAAAAACAGTTG
AAGATAATTTAAGTGAATTAATTTTAGAAGGTAATCAAATCGAAGGTAAAGCAGTGACTATCGATCATGATGGTACGGAG
TTTAAATATGATATTCATGATAGAACTGCTAATTCTGAAGAAGAAATGACTCAAGCATAG

Protein sequence :
MLFGRLTERAQRVLAHAQEEAIRLNHSNIGTEHLLLGLMKEPEGIAAKVLESFNITEDKVITEVEKLIGHGQEQAGTLRY
TPRAKKVIELSMDEARKLHHNFVGTEHILLGLIRENEGVAARVFANLDLNITKARAQVVKALGSPEMGTKNAQTNKSNNT
PTLDSLARDLTVIAKDGTLDPVIGRTKEITRVIEVLSRRTKNNPVLIGEPGVGKTAIAEGLAQAIINNEVPETLKDKRVM
SLDMGTVVAGTKYRGEFEERLKKVMEEIHQAGNVILFIDELHTLVGAGGAEGAIDASNILKPALARGELQCIGATTLDEY
RKNIEKDAALERRFQPVQVDEPSVEDTIEILKGLRDRYEAHHRINISDQALDAAAKLSDRYVSDRFLPDKAIDLIDEASS
KVRLRSHTTPTNLKSIEQEIETVKKEKDAAVHAQEFENAANLRDKQSKLEKQYEDAKKEWQNAQGGSNTELSQEDIAEVI
AGWTGIPLTKINETESDRLLNLEATLHGRVIGQNDAVTSISKAVRRARAGLKDPKRPIGSFIFLGPTGVGKTELARALAE
TMFGEEDAMIRVDMSEFMEKHAVSRLVGAPPGYVGHDDGGQLTEKVRRKPYSVILFDEIEKAHPDVFNILLQVLDDGHLT
DTKGRRVDFRNTVIIMTSNVGAQELQDQRFAGFGGASEGQDYETIRKTMMKELKNAFRPEFLNRVDDIIVFHKLSKDELK
EIVTMMVNKLTQRLSEQDIQIEVTDKAKEVIAEEGYDPEYGARPLIRAIQKTVEDNLSELILEGNQIEGKAVTIDHDGTE
FKYDIHDRTANSEEEMTQA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
clpC YP_005163377.1 ATP-dependent Clp protease ATP-binding subunit Not tested Not named Protein 0.0 57
STY0294 NP_454876.1 ClpB-like protein Not tested SPI-6 Protein 2e-106 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
SLGD_02364 YP_003472579.1 ATP-dependent Clp protease, ATP-binding subunit ClpC/Negative regulator of genetic competence clcC/mecB VFG0079 Protein 0.0 71
SLGD_02364 YP_003472579.1 ATP-dependent Clp protease, ATP-binding subunit ClpC/Negative regulator of genetic competence clcC/mecB VFG0080 Protein 5e-164 52