Gene Information

Name : topB (XBJ1_1548)
Accession : YP_003467455.1
Strain : Xenorhabdus bovienii SS-2004
Genome accession: NC_013892
Putative virulence/resistance : Unknown
Product : DNA topoisomerase III
Function : -
COG functional category : L : Replication, recombination and repair
COG ID : COG0550
EC number : 5.99.1.2
Position : 1503162 - 1505156 bp
Length : 1995 bp
Strand : -
Note : Evidence 2b : Function of strongly homologous gene; PubMedId : 11395412; Product type e : enzyme

DNA sequence :
ATGCCACTGTATTTATGTGAAAAGCCCTCTCAGGCCAGAGATATCGCCCGGGTGCTGGGCGTGAAGCAGCGCGGACAGGG
CTATCTCTTTGGCGACAGTATTACTGTCACCTGGGCTATCGGGCATTTGCTGGAAATGGCTGCACCCGAGCACTATGGTG
AACAATTCGGCCCGCCGTGGCGCATGGAACCCCTGCCGGTGCTGCCTGTGCAGTGGCAATGGACTGTGAAGAAAGAGACC
GCCGATCAGTTTGCGGTGATCAGACAATTACTGAAACAGGCCGACGAAGTGATTATCGCCACTGATGCTGACCGTGAAGG
GGAAGTGATTGCCCGTGAACTGCTGGAGTATTGCCGTTTTACCGGCCCCGTCAGACGGCTGTGGCTGTCTGCGCTGGATG
AAACCAGTATCCGGCAGGCACTGGCCGCGATATTACTGGGGGAGCAAACCGAACCACTCTGGCAGGCCGGACTGGGACGG
GCACGGGCGGACTGGCTGATGGGAATAAACCTGACCCGCCTGTATACCCTGAAAGCGCAGGCACAGGGATTTGGTGAGGT
GCTGTCCATCGGGCGGGTACAGACGCCGACACTGGCACTGGTCGTGAACCGTGATAACGATATCGCCCGGTTTGAGCCAA
AACCCTACTGGCAGGTGATGGCCGCATTGCAAAAAGATGACATTAGCTTTCGGGTTAAATGGCTGCCTGCGCCCGACGAT
TGCGATGAAGAAAAACGCTGTATCCGGGAGGATATCGCGCAGAGTGTGGTTCAGCGTTGTCAGCAGGCACAAGATGCCGT
GGTGACTGAACTCACGCAGAAACGGGAAAAAACCCCGCCGCCGCTCTGTTTTGATTTGGGGATGCTCCAGCAGGTAGCCT
CCCGTCAATGGGGAATGGGGGCCGGTCAGGTACTGACGATTGCCCAGTCGTTGTATGAAATCCATAAAGCGACCACCTAC
CCGCGCACGGATTGCGGTTATCTGCCGGTTTCAATGCGGGAAGATATTCCGGCCGTGTTCACCGCACTGACCCGTACCGA
TCCTGCGATGAATGCCATTATCAGCCAGCTGGATGCCAGCACTCTCTCCCGAGTCTGGAATGACAGCCAAATCACGGCGC
ACCATGCCATTATTCCGACCCGCCACACTTTTGATATGACGAAACTGACCGCGGACGAATTAAAGATCTATCAGTTGATC
CGCCACTATTATCTGGCGCAGTTTCTGCCCGTACAGGAAACGGATGTGACTGACGTGACATTCACTATCGGCGGGCAGGT
ATTTCAGGCGAAAGGGCGGGTCAGTGTGGTCACGGGCTGGAAGACGCTGTTTGCCGATGAAAAACAGGTGCAGGAGCAGG
ACGACAATACCGCGCTGCCTGCATTGAAAAAAGAGGAAATCTGCCCGGTACTCCGTGCAGAAATACAGCCCCGGCAAACC
CGGCCGCCTGCGCCTTTTACCGAAGGTACGCTGATTGCCGCCATGAAAAATGCCGCTGCGTTTATCCACGATCCGCAGCT
TAAAAAAGTGCTGCGGGAAAATGCCGGGCTGGGCACGGAGGCCACCCGGGCAGGTATCATTGAAGCCCTGTTTAACCGTC
AGCTGCTGGCGCGAAAAAAGAAAAACCTGCATGCAACGCCGCTGGCGCAGGAGCTGATTGCCGGGCTGCCGGACGTCCTG
ACCCATCCGGGGATGACTGCGCTGTGGGAACAGTCTCTGGACGACATTGCCCGGGGCCGGGCCACACTGGATGGCTTTAT
GCAGAAACAGGCACAATGGCTGGCGCATTTAGTGGAAAAGGGCAAAACACAGCCGATCCGGTTTACCCTGCCGAAAACCC
CGGCGTGCCCGCGCTGTGGCGGCCCGATGCAAAAACGGGCGGGAAAAACAACCCCGTTCTGGGGCTGCACTCGCTATCCG
GCATGCAAAGGGATGCTGAACGCTAACGCGGTGACCGGCTCCCGAAAAACCCGGCGGGGAAATTCACCGGACTGA

Protein sequence :
MPLYLCEKPSQARDIARVLGVKQRGQGYLFGDSITVTWAIGHLLEMAAPEHYGEQFGPPWRMEPLPVLPVQWQWTVKKET
ADQFAVIRQLLKQADEVIIATDADREGEVIARELLEYCRFTGPVRRLWLSALDETSIRQALAAILLGEQTEPLWQAGLGR
ARADWLMGINLTRLYTLKAQAQGFGEVLSIGRVQTPTLALVVNRDNDIARFEPKPYWQVMAALQKDDISFRVKWLPAPDD
CDEEKRCIREDIAQSVVQRCQQAQDAVVTELTQKREKTPPPLCFDLGMLQQVASRQWGMGAGQVLTIAQSLYEIHKATTY
PRTDCGYLPVSMREDIPAVFTALTRTDPAMNAIISQLDASTLSRVWNDSQITAHHAIIPTRHTFDMTKLTADELKIYQLI
RHYYLAQFLPVQETDVTDVTFTIGGQVFQAKGRVSVVTGWKTLFADEKQVQEQDDNTALPALKKEEICPVLRAEIQPRQT
RPPAPFTEGTLIAAMKNAAAFIHDPQLKKVLRENAGLGTEATRAGIIEALFNRQLLARKKKNLHATPLAQELIAGLPDVL
THPGMTALWEQSLDDIARGRATLDGFMQKQAQWLAHLVEKGKTQPIRFTLPKTPACPRCGGPMQKRAGKTTPFWGCTRYP
ACKGMLNANAVTGSRKTRRGNSPD

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
PMI2630 YP_002152332.1 DNA topoisomerase III Not tested Not named Protein 0.0 58
topB NP_807836.1 DNA topoisomerase III Not tested SPI-7 Protein 0.0 57
topB AAF14809.1 topoisomerase B Not tested SPI-7 Protein 0.0 57
topB NP_458624.1 topoisomerase B Not tested SPI-7 Protein 0.0 57
pph56 CAI36097.1 Topoisomerase IA Not tested PPHGI-1 Protein 7e-160 48
topB AAN62317.1 putative DNA topoisomerase III Not tested PAGI-3(SG) Protein 2e-153 47
topB1 YP_005176228.1 DNA topoisomerase III Not tested ICEPmu1 Protein 4e-149 47
topB AAN62194.1 putative DNA topoisomerase III Not tested PAGI-2(C) Protein 5e-162 46
topB AAW83109.1 TopB Not tested GGI Protein 1e-125 41