Gene Information

Name : TK90_0077 (TK90_0077)
Accession : YP_003459330.1
Strain : Thioalkalivibrio sp. K90mix
Genome accession: NC_013889
Putative virulence/resistance : Resistance
Product : D-Ala-D-Ala dipeptidase
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG2173
EC number : 3.4.13.22
Position : 85851 - 86546 bp
Length : 696 bp
Strand : +
Note : PFAM: peptidase M15D vanX D-ala-D-ala dipeptidase; KEGG: sfu:Sfum_0509 peptidase M15D, VanX D-ala-D-ala dipeptidase

DNA sequence :
ATGCGCTTAATGAGTCTGTGGCTGGCCGGTCTGGTCCTGGTCTGGCCGATCGTCGCCAGCGCGGATGAGGCGTGGCCGCC
GGGATTCGTGGCGGCCCGCGACGTGGTGCCGGGGTTGGTCGAGGAGATCCGCTATTTCGGCGAAGACAACTTCGTCGGCG
AGCCCATTGACGGCTATGAGGCGCCGGTTTGCATCCTTACCGTCCCGGCTGCCGAGGCGCTGGCCGGGGTGCAGGAACGC
CTGAAGCCGTTTGGGCTCGGGATCAAGGTGTTTGACTGTTACCGCCCCCAGCAGGCGGTGGACCATTTCGTGCGCTGGGC
GGCGGACCCGGACGCAACGGAGATGCAGGAGCGCTATTACCCGAACGTGCCCAAGGACGAGTTGTTCGAGCGCGGCTATA
TCGCGGAGCAGTCCACCCATTCGCGCGGCTCCACGGTCGATGTCACCCTCGTTGATCGCGAAACCGGCAGCGAGCTGGAC
ATGGGGACCGACTTCGACCGCTTCAGTCCGCGCTCCTGGCCGGACGCGGCCGATGCCACACCACAGCAGCGCGCGAACCG
CGTCCTGCTACAGCGCCTGATGGTGGAGGCGGGCTTCGAGCCCTACGCCCAGGAGTGGTGGCACTTCACGCTGGCCAACG
AACCCTTCCCTGAGACTTCGTTCGACTTCCCCGTGGCTCACCCGCCCCGCGACTGA

Protein sequence :
MRLMSLWLAGLVLVWPIVASADEAWPPGFVAARDVVPGLVEEIRYFGEDNFVGEPIDGYEAPVCILTVPAAEALAGVQER
LKPFGLGIKVFDCYRPQQAVDHFVRWAADPDATEMQERYYPNVPKDELFERGYIAEQSTHSRGSTVDVTLVDRETGSELD
MGTDFDRFSPRSWPDAADATPQQRANRVLLQRLMVEAGFEPYAQEWWHFTLANEPFPETSFDFPVAHPPRD

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
vanX NP_815950.1 D-alanyl-D-alanine dipeptidase Not tested Not named Protein 1e-34 42
vanXB YP_008394260.1 D-alanyl-D-alanine dipeptidase Not tested Not named Protein 1e-33 41

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
TK90_0077 YP_003459330.1 D-Ala-D-Ala dipeptidase U82965.2.orf32.gene. Protein 5e-35 45
TK90_0077 YP_003459330.1 D-Ala-D-Ala dipeptidase FJ349556.1.orf5.gene Protein 3e-33 43
TK90_0077 YP_003459330.1 D-Ala-D-Ala dipeptidase U35369.1.gene7.p01 Protein 9e-35 42
TK90_0077 YP_003459330.1 D-Ala-D-Ala dipeptidase AE016830.1.gene2249. Protein 6e-35 42
TK90_0077 YP_003459330.1 D-Ala-D-Ala dipeptidase AF130997.1.orf5.gene Protein 6e-32 41
TK90_0077 YP_003459330.1 D-Ala-D-Ala dipeptidase AF310956.2.orf6.gene Protein 5e-34 41
TK90_0077 YP_003459330.1 D-Ala-D-Ala dipeptidase NC_005054.2598281.p0 Protein 9e-33 41
TK90_0077 YP_003459330.1 D-Ala-D-Ala dipeptidase M97297.gene.p01 Protein 9e-33 41
TK90_0077 YP_003459330.1 D-Ala-D-Ala dipeptidase NC_014475.1.orf4.gen Protein 9e-33 41
TK90_0077 YP_003459330.1 D-Ala-D-Ala dipeptidase AF155139.2.orf6.gene Protein 3e-33 41