Gene Information

Name : TK90_0611 (TK90_0611)
Accession : YP_003459862.1
Strain : Thioalkalivibrio sp. K90mix
Genome accession: NC_013889
Putative virulence/resistance : Virulence
Product : nucleotide sugar dehydrogenase
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG0677
EC number : -
Position : 648337 - 649626 bp
Length : 1290 bp
Strand : -
Note : TIGRFAM: nucleotide sugar dehydrogenase; PFAM: UDP-glucose/GDP-mannose dehydrogenase; UDP-glucose/GDP-mannose dehydrogenase dimerisation; UDP-glucose/GDP-mannose dehydrogenase; KEGG: hna:Hneap_0232 nucleotide sugar dehydrogenase

DNA sequence :
ATGGCGGAATTTGCGGCACCGGACGCCCCGCGTCTGGCCATAATTGGTCTGGGTTATGTCGGCCTGCCCCTGGCAGCCGA
GTTCGGACGGGTCCTTCCCACGCTGGGCTTCGATATCGATACGGGCCGCGTCGAGGAACTGCGCGGCGGACACGACCGCA
CACGCGAGGTCTCCCGCGAGGAACTCGCCGCCGCCGAGCATCTGGAACTGACCGCGGATCCGGGGCGACTGCAGGACTGC
AACGTGTTCATCGTGACGGTGCCCACCCCGATCGATGCCCACCGGCGGCCGGACCTGGGCCCGCTGCTGGCGGCCAGCCG
CACGGTGGGTCGCGCCCTGAAGCCAGGGGACGTGGTGATCTACGAGTCCACCGTCTACCCCGGCGCGACCGAGGAAGACT
GTGCCCCTGTGCTGGCCACGGAATCCGGCCTCGAGCTCAACCGCGATTTTTTCCTCGGCTACAGCCCCGAGCGGGTGAAC
CCCGGCGACAAGGAACACCGCATTCCCGATATCGTCAAGGTCACCTCCGGCTCCACCCCCGAGGTCGCAGAATTCGTCAA
CGCGCTCTATGCCCGCATCATCCGCGCCGGCACCCACCCGGCTGCCAGTATTCGCGTAGCCGAGGCGGCCAAGGTGATCG
AGAACACCCAGCGCGACGTGAACATCGCCCTGATCAACGAACTCGCGATGCTGTTCGAACGCCTGGACCTGGATACCGAG
GCCGTGCTGGCCGCGGCCGGGACCAAGTGGAACTTTCTGCCATTCCGACCCGGCCTGGTGGGCGGGCACTGCATTGGCGT
CGACCCGTACTACCTGACGCACAAGGCACAGGCCGCTAACTACCACCCGGAGATGATCCTCGCCGGCCGCCGCACCAACG
ACGGCATGGGCGGCTACATCGCGGATCGCACGATCAAGTCGATGATCCGCAAAGGGTTCCCGGTCGTGGCCTCGCGTGTC
CTGGTGATGGGGCTCGCGTTCAAGGAAAACTGCCCGGATCTGCGCAATACGCGCGTGGTGGACATCATCCATGACCTGCA
CGGCTACAACGCCGAAGTCGATGTCTGGGACCCCTGGGTGGATACCGCCGAGGCCCGTCACGAGTATGGCCTGGACCTGC
TGACCGAGGCGCCGAAACAGGGCCAGTACGACGCCATCATCCTTGCGGTTCCGCACCACGAGTTCGTCGAACTCGGCGCC
CAGGGCCTGCAGAAATTCGGGCGCGAACGCGCGGTGATCTTCGACGTGAAATCGGTACTCCCGCCCGAGGCGAGTGACCT
GCGTCTATAA

Protein sequence :
MAEFAAPDAPRLAIIGLGYVGLPLAAEFGRVLPTLGFDIDTGRVEELRGGHDRTREVSREELAAAEHLELTADPGRLQDC
NVFIVTVPTPIDAHRRPDLGPLLAASRTVGRALKPGDVVIYESTVYPGATEEDCAPVLATESGLELNRDFFLGYSPERVN
PGDKEHRIPDIVKVTSGSTPEVAEFVNALYARIIRAGTHPAASIRVAEAAKVIENTQRDVNIALINELAMLFERLDLDTE
AVLAAAGTKWNFLPFRPGLVGGHCIGVDPYYLTHKAQAANYHPEMILAGRRTNDGMGGYIADRTIKSMIRKGFPVVASRV
LVMGLAFKENCPDLRNTRVVDIIHDLHGYNAEVDVWDPWVDTAEARHEYGLDLLTEAPKQGQYDAIILAVPHHEFVELGA
QGLQKFGRERAVIFDVKSVLPPEASDLRL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
tviB NP_458740.1 Vi polysaccharide biosynthesis protein, UDP-glucose/GDP-mannose dehydrogenase Virulence SPI-7 Protein 7e-127 58
tviB NP_807945.1 VI polysaccharide biosynthesis UDP-glucose/GDP-mannose dehydrogenase Virulence SPI-7 Protein 7e-127 58
cap1L AAA64651.1 type 1 capsule synthesis gene Virulence SCCcap1 Protein 2e-106 53

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
TK90_0611 YP_003459862.1 nucleotide sugar dehydrogenase VFG0431 Protein 3e-127 58