Gene Information

Name : TK90_2543 (TK90_2543)
Accession : YP_003461768.1
Strain : Thioalkalivibrio sp. K90mix
Genome accession: NC_013889
Putative virulence/resistance : Virulence
Product : nucleotide sugar dehydrogenase
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG0677
EC number : -
Position : 2679659 - 2680948 bp
Length : 1290 bp
Strand : +
Note : TIGRFAM: nucleotide sugar dehydrogenase; PFAM: UDP-glucose/GDP-mannose dehydrogenase; UDP-glucose/GDP-mannose dehydrogenase dimerisation; UDP-glucose/GDP-mannose dehydrogenase; KEGG: bpt:Bpet4030 polysaccharide biosynthesis protein

DNA sequence :
ATGCATGCACTCCCCTCATTGGAAGAGATTCGCCTCGGGGTTATCGGACTGGGCTATGTCGGCCTGCCCCTGGCGGTCGA
GTTCGGCCGGGTCTGGCCGACCCTGGGATTCGATATCCAGCCCGGACGCATCCAGGACCTGAAGAACGGGATTGATCGTA
CCCGCGAGGTCGAGCCGGAGGATCTCGCTGCGGCGACGCACCTGGACTACACCACGGAGCTCGAGGCACTCCGCCCGTGC
AATGTGTTCGTGGTGACCGTGCCGACGCCGATCGATGCCCACCGCCGCCCGGACCTGCGCCCCCTGCTCGGGGCCACCCA
TACCGTGGGGCAGGTGCTCAAGCGCGGCGACGTGGTGATCTACGAGTCGACGGTCTATCCGGGGGCGACGGAGGAAGACT
GCGTCCCGATCCTGGAACGGGAATCCGGGCTGATCCACAACGAGGACTTCTTCACCGGCTACAGTCCCGAGCGGATCAAT
CCCGGGGACAAGGCGCACCGAGTCACCTCCATCAAGAAGGTCACCTCGGGCTCGCTGCCGGAGGTGGCGGACTTCGTCGA
CGCCCTGTATGCGCGCGTCATCACCGCCGGCACGCACAAGGCCGAGAGTATCCGCGTGGCCGAGGCGGCCAAGGTGATCG
AGAACACCCAGCGTGACGTCAACATCGCCCTGATCAACGAGCTGGCACTGCTGTTCGAGCGCCTGGGCCTCGATACCGAG
GCGGTCCTGCAGGCCGCCGGGACCAAGTGGAATTTCCTGCCGTTCCGGCCCGGGCTGGTCGGCGGGCACTGCATCGGGGT
GGACCCGTACTACCTGACGCACAAGGCCCAGGCCGTCGGACACCACCCGGAGATGATCCTGGCAGGGCGCCGCGTGAACG
ACGCGATGGGGGCCCACATCGCGGACGCGACCATCCGTGCGCTGGTGCGCAAGGGAATCAATCCGGTGGGGACACGCATC
CTGCTGATGGGCCTGACCTTCAAGGAGAACTGCCCAGACCTGCGCAATACGCGCGTGATGGACATCTACCATACGCTGCG
CGGATACAACACGGAGGTCGTGGTGTTCGACCCCTGGGTCGATCCGGAGGAGGCCGAACACGAATACGGCATCACCCCGA
TCACCTCGGCCCCCGAGGCGGATTCGTTCGACGCCATCATCGTGGCGGTGCCCCACCAGGCGTTCCTGGACATGGGAGTG
GAAGCGATCCGTGCGCTCGCGCACCCGCAGGCGGTCCTGTTCGATGTGAAATCGGTCTTCCCGCGCGAGGCCAGCGACCT
GCGCCTGTGA

Protein sequence :
MHALPSLEEIRLGVIGLGYVGLPLAVEFGRVWPTLGFDIQPGRIQDLKNGIDRTREVEPEDLAAATHLDYTTELEALRPC
NVFVVTVPTPIDAHRRPDLRPLLGATHTVGQVLKRGDVVIYESTVYPGATEEDCVPILERESGLIHNEDFFTGYSPERIN
PGDKAHRVTSIKKVTSGSLPEVADFVDALYARVITAGTHKAESIRVAEAAKVIENTQRDVNIALINELALLFERLGLDTE
AVLQAAGTKWNFLPFRPGLVGGHCIGVDPYYLTHKAQAVGHHPEMILAGRRVNDAMGAHIADATIRALVRKGINPVGTRI
LLMGLTFKENCPDLRNTRVMDIYHTLRGYNTEVVVFDPWVDPEEAEHEYGITPITSAPEADSFDAIIVAVPHQAFLDMGV
EAIRALAHPQAVLFDVKSVFPREASDLRL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
tviB NP_458740.1 Vi polysaccharide biosynthesis protein, UDP-glucose/GDP-mannose dehydrogenase Virulence SPI-7 Protein 1e-133 60
tviB NP_807945.1 VI polysaccharide biosynthesis UDP-glucose/GDP-mannose dehydrogenase Virulence SPI-7 Protein 1e-133 60
cap1L AAA64651.1 type 1 capsule synthesis gene Virulence SCCcap1 Protein 8e-111 54

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
TK90_2543 YP_003461768.1 nucleotide sugar dehydrogenase VFG0431 Protein 5e-134 60