Gene Information

Name : TK90_1523 (TK90_1523)
Accession : YP_003460763.1
Strain : Thioalkalivibrio sp. K90mix
Genome accession: NC_013889
Putative virulence/resistance : Resistance
Product : Gentamicin 3'-N-acetyltransferase
Function : -
COG functional category : R : General function prediction only
COG ID : COG0456
EC number : 2.3.1.60
Position : 1621726 - 1622325 bp
Length : 600 bp
Strand : +
Note : PFAM: GCN5-related N-acetyltransferase; KEGG: sal:Sala_0626 gentamicin 3'-N-acetyltransferase

DNA sequence : 
ATGGCGGCTGACCCGGCACCCCCGCAGCACGAGCGGTCCTTGCTCAAGATCCGGCGCCTTGGTCCGGCGGATCGGGCAGC
CGCGCACGCCCTGCTCGACCTGTTTGCACACGTGTTCGAGGAACCGGACACCTACTCGGGTGCACGTCCCTCCGACGAGT
ACCTCAAGCGCTTGCTGGCTCGAGAAACGTTCATCGCCCTGATTGCCGAAACGGAAGGCCGGGTCGTCGGCGGGCTGGTC
GCCTATGTCCTGGACAAGCTCGAACAGGCCCGCAGCGAGGTCTACATCTATGACCTCGCCGTGGCCGACAACTTCCGCCG
GCGCGGCATTGCCACGGCCCTGATCCGCCACACCCAGGCCATCGCCGCCGAGTTGGGTGCCTGGGTGGTATTCGTCCAGG
CTGACCGCACCGACAATGCCGCGATAGCGCTCTACAGCGGGCTGGGCCAGCGCGAGGACGTGCTCCACTTCGACTTGCCC
CTGAACAATCCCCGTAATGCACCTCCACCGCACCCGGACACCAACCCGGGGAACGCCGACGTTCCCAACACGGGGGCCTT
CGGAATCAAGCGCTCCGAACCAGGAGACGAGACGCCATGA

Protein sequence : 
MAADPAPPQHERSLLKIRRLGPADRAAAHALLDLFAHVFEEPDTYSGARPSDEYLKRLLARETFIALIAETEGRVVGGLV
AYVLDKLEQARSEVYIYDLAVADNFRRRGIATALIRHTQAIAAELGAWVVFVQADRTDNAAIALYSGLGQREDVLHFDLP
LNNPRNAPPPHPDTNPGNADVPNTGAFGIKRSEPGDETP

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
acc(3)Ic ACY75521.1 Aac(3) Ic Not tested Tn6060 Protein 7e-31 54
aacC1/aacCA1 ACV89836.1 type A aminoglycoside-(3)-acetyltransferase AacC1 or AacC-A1 or AAC-(3)-Ia Not tested AbaR7 Protein 3e-28 53
aacC1 AFV53117.1 aminoglycoside (3) acetyltransferase AacC1 or AacC-A1 or AAC(3)-Ia Not tested AbGRI2-1 Protein 3e-28 53
aacCA1 AGK36643.1 aminoglycoside-(3)-acetyltransferase AacC1 or AacC-A1 or AAC-(3)-Ia Not tested AbaR26 Protein 3e-28 53
aacC1/aacCA1 ACN81021.1 aminoglycoside-(3)-acetyltransferase AacC1 or AacC-A1 or AAC-(3)-Ia Not tested AbaR5 Protein 5e-28 53
aac3 CAJ77083.1 Aminoglycoside 3-acetyltransferase Not tested AbaR1 Protein 2e-28 53
aacC1/aacCA1 ACV89833.1 type A aminoglycoside-(3)-acetyltransferase AacC-A1 or AacC1 or AAC-(3)-Ia Not tested AbaR7 Protein 2e-28 53
aacC1 AFV53118.1 aminoglycoside (3) acetyltransferase AacC1 or AacC-A1 or AAC(3)-Ia Not tested AbGRI2-1 Protein 2e-28 53
aacC1 YP_005797146.1 aminoglycoside N(3')-acetyltransferase I Not tested AbaR4e Protein 3e-28 53
aacC1/aacCA1 ACN81020.1 aminoglycoside-(3)-acetyltransferase AacC-A1 or AacC1 or AAC-(3)-Ia Not tested AbaR5 Protein 3e-28 53

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
TK90_1523 YP_003460763.1 Gentamicin 3'-N-acetyltransferase AF318077.1.gene3.p01 Protein 2e-28 54
TK90_1523 YP_003460763.1 Gentamicin 3'-N-acetyltransferase NC_010410.6002585.p0 Protein 1e-28 53
TK90_1523 YP_003460763.1 Gentamicin 3'-N-acetyltransferase NC_011586.7045205.p0 Protein 1e-28 53
TK90_1523 YP_003460763.1 Gentamicin 3'-N-acetyltransferase U04610.gene.p01 Protein 3e-28 52