Gene Information

Name : TK90_1161 (TK90_1161)
Accession : YP_003460406.1
Strain : Thioalkalivibrio sp. K90mix
Genome accession: NC_013889
Putative virulence/resistance : Virulence
Product : flagellar protein export ATPase FliI
Function : -
COG functional category : N : Cell motility
COG ID : COG1157
EC number : 3.6.3.14
Position : 1237576 - 1238952 bp
Length : 1377 bp
Strand : +
Note : KEGG: csa:Csal_1958 ATPase FliI/YscN; TIGRFAM: flagellar protein export ATPase FliI; ATPase, FliI/YscN family; PFAM: H+transporting two-sector ATPase alpha/subunit beta central region; SMART: ATPase AAA

DNA sequence :
ATGAGCTCCCCCGTCGACACCCTGCGCAAGCGGGGGCAAGAGCAACTGACCACCGGGCTTCTGGATCGTCTGCAGCAGTC
GCGTGGCCGGCTGGAGCGCGTGCAACCGCCTCAGTCTGAAGGCCGCCTGTCGCGGCTGACCGGCCTGACCTTCGAGGCCG
AAGGACTGCGCCTGCCGATGGGGGGGCGAGCGCTGATCCACGGCGAGAATGGCGCGGCCGTCCCGGCCGAGGTGGTGGGG
TTCCAGAACGACCGCACCTTTCTGATGCCGGAGGAGCTGGCCTCGGGCCTGACGCCCGGTGCGCGCATTGAACCACTGGA
TATCCAACGCGAGATCCCGGTCGGGGACGCGCTGCTCGGGCGCGTGATCGATGCCAATGGCCAGCCGCTGGATGGGAAAG
GGCCCTTGCGCGCGCGCGACCACAGTCCGCTGTCGGGCCGCCCGATCAACCCGCTACAGCGGGCGCCGGTGCGGGAACCG
CTGGATGTCGGGATACGCTCGATCAACGGGCTGCTGTCGGTCGGGAGGGGACAACGGCTGGGCCTGTTCGCCGGCTCCGG
TGTCGGGAAGAGTGTCTTGCTCGGGATGATGACGCGCAACACCAGTGCCGATGTGATCGTGGTTGGTTTGATCGGCGAGC
GTGGTCGCGAAGTGAATGAATTCATCCACGAGATTCTGGACGAGGAGTCCCGCCAGAGAACCGTGGTCGTAGCCGTGCCT
GCCGATCAGTCGCCACTGCTTCGCCAGCACGGCGCCTGGGTGGCCACTACGGTCGCGGAATCCTTCCGCGACCGTGGGCT
CAATGTGCTGCTGTTGATGGATTCGCTCACGCGCTTTGCTCAAGGGGCGCGCGAGATCGCGATGGCGATTGGCGAGCCAC
CAGCCTCCAAGGGCTATGCCGCCTCGGTGTTTGCGCGTCTGCCGCAATTGGTGGAGCGAGCCGGTAACGGCGATGTGGGC
GGTGGTTCGATCACGGCGTTCTATACGGTGCTGGCCGAGGGGGATGACCAGAACGATCCGATCGTGGATGCGGCGCGTGC
GATCCTCGACGGGCACGTGGTCCTGTCGCGCGAGATCGCGGAGACCGGGCGCTATCCCGCGATCGACGTGTCGGCGTCGG
TCTCGCGAGTGATGAGCGCGCTGATCACGCCGGAGCACGAGCAGGCGGCCCGGCGCTTCCGGGATCTTGCCTCGACCTAC
ATGCGCAACCGCGACCTGATTGCCGTGGGCGCCTACCGCAGGGGGGCGGATACCCATCTGGACGAAGCGGTGGCGATGCA
CGAGCGGCTGGAGGCCTATCTTGGACAGGGCCGCGACGAGGCGGTCGGGTTTGATCAGGCCCGCGACGAACTCCTGGCCT
TGATCGGGGGCGCCTGA

Protein sequence :
MSSPVDTLRKRGQEQLTTGLLDRLQQSRGRLERVQPPQSEGRLSRLTGLTFEAEGLRLPMGGRALIHGENGAAVPAEVVG
FQNDRTFLMPEELASGLTPGARIEPLDIQREIPVGDALLGRVIDANGQPLDGKGPLRARDHSPLSGRPINPLQRAPVREP
LDVGIRSINGLLSVGRGQRLGLFAGSGVGKSVLLGMMTRNTSADVIVVGLIGERGREVNEFIHEILDEESRQRTVVVAVP
ADQSPLLRQHGAWVATTVAESFRDRGLNVLLLMDSLTRFAQGAREIAMAIGEPPASKGYAASVFARLPQLVERAGNGDVG
GGSITAFYTVLAEGDDQNDPIVDAARAILDGHVVLSREIAETGRYPAIDVSASVSRVMSALITPEHEQAARRFRDLASTY
MRNRDLIAVGAYRRGADTHLDEAVAMHERLEAYLGQGRDEAVGFDQARDELLALIGGA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
YPO0267 YP_002345348.1 type III secretion system ATPase Virulence Not named Protein 6e-81 49
hrpB6 AAF61281.1 HrpB6 Virulence Hrp PAI Protein 3e-86 47
hrcN AAP34339.1 HrcN Virulence Hrp PAI Protein 6e-87 47
hrcN YP_198730.1 type III secretion system ATPase Virulence Hrp PAI Protein 4e-86 47
hrcN NP_640767.1 type III secretion system ATPase Virulence Hrp PAI Protein 3e-86 47
hrpB6 BAB07852.1 HrpB6 Virulence Hrp PAI Protein 3e-86 47
hrcN YP_362163.1 type III secretion system ATPase Virulence Hrp PAI Protein 1e-84 47
hrpB6 AAB08461.1 HrpB6 Virulence Hrp PAI Protein 7e-85 47
XC_3006 YP_244074.1 type III secretion system ATPase Virulence Hrp PAI Protein 3e-83 46
hrcN NP_636610.1 type III secretion system ATPase Virulence Hrp PAI Protein 3e-83 46
hrcN AAG33879.1 HrcN Virulence Hrp PAI Protein 3e-72 46
escN AFO66300.1 putative LEE-encoded type III secretion system ATPase Virulence SESS LEE Protein 3e-74 46
escN AFO66415.1 putative LEE-encoded type III secretion system ATPase Virulence SESS LEE Protein 3e-74 46
hrcN ABQ88354.1 HrcN Virulence Hrp PAI Protein 4e-69 46
hrpJ4 AAA81942.1 HrpJ4 Virulence Hrp PAI Protein 4e-69 46
hrcN AAR25633.1 type III secretion cytoplasmic ATPase HrcN Not tested Not named Protein 4e-76 45
lscN AAO18044.1 LscN Virulence TTSS locus Protein 2e-75 45
escN AAC31513.1 L0034 Virulence LEE Protein 2e-75 45
escN YP_003223475.1 translocator EscN Virulence LEE Protein 5e-75 45
unnamed ACU09458.1 type III secretion apparatus H+-transporting two-sector ATPase Virulence LEE Protein 2e-75 45
escN AAC38383.1 EscN Virulence LEE Protein 1e-75 45
escN NP_290268.1 hypothetical protein Virulence LEE Protein 3e-75 45
ECs4568 NP_312595.1 EscN Virulence LEE Protein 3e-75 45
escN CAI43874.1 EscN protein Virulence LEE Protein 4e-75 45
ssaN NP_460380.1 type III secretion system ATPase Virulence SPI-2 Protein 2e-74 44
ssaN YP_216423.1 type III secretion system ATPase Virulence SPI-2 Protein 1e-74 44
ssaN CAA70537.1 secretion system apparatus Virulence SPI-2 Protein 2e-74 44
ssaN NP_456113.1 putative type III secretion ATP synthase Virulence SPI-2 Protein 4e-74 44
ssaN NP_805086.1 type III secretion system ATPase Virulence SPI-2 Protein 4e-74 44
hrcN AAT96195.1 HrcN Virulence T-PAI Protein 2e-72 44
hrcN AAT96141.1 HrcN Virulence T-PAI Protein 1e-72 44
ysaN AAS66842.1 YsaN Not tested SSR-1 Protein 5e-70 44
ECs3730 NP_311757.1 ATP synthase SpaL Not tested LIM Protein 2e-61 44
unnamed AAL06369.1 EscN Virulence LEE Protein 4e-74 44
hrcN NP_791227.1 type III secretion cytoplasmic ATPase HrcN Virulence Hrp PAI Protein 2e-72 43
escN YP_003232153.1 T3SS structure protein EscN Virulence LEE Protein 4e-75 43
escN YP_003236088.1 translocator EscN Virulence LEE Protein 1e-75 43
invC AAS66861.1 InvC Not tested SSR-2 Protein 3e-64 43
hrcN AAT96339.1 HrcN Virulence S-PAI Protein 1e-71 42
hrcN AAT96299.1 HrcN Virulence S-PAI Protein 6e-72 42
hrcN AAT96258.1 HrcN Virulence S-PAI Protein 5e-72 42
hrcN AAB06001.1 HrcN Virulence Hrp PAI Protein 5e-72 42
escN AAK26715.1 EscN Virulence LEE Protein 9e-75 42
escN AAL57542.1 EscN Virulence LEE Protein 9e-75 42
escN CAC81862.1 EscN protein Virulence LEE II Protein 3e-75 42
invC YP_217813.1 ATP synthase SpaL Virulence SPI-1 Protein 1e-62 42
spaI NP_457288.1 secretory apparatus ATP synthase (associated with virulence) Virulence SPI-1 Protein 1e-62 42
spaI NP_806497.1 ATP synthase SpaL Virulence SPI-1 Protein 1e-62 42
invC NP_461815.1 ATP synthase SpaL Virulence SPI-1 Protein 1e-62 42
hrcN ABA47275.1 HrcN Virulence S-PAI Protein 1e-75 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
TK90_1161 YP_003460406.1 flagellar protein export ATPase FliI VFG1254 Protein 1e-117 61
TK90_1161 YP_003460406.1 flagellar protein export ATPase FliI VFG2499 Protein 1e-119 59
TK90_1161 YP_003460406.1 flagellar protein export ATPase FliI VFG2331 Protein 2e-115 56
TK90_1161 YP_003460406.1 flagellar protein export ATPase FliI VFG0812 Protein 1e-75 45
TK90_1161 YP_003460406.1 flagellar protein export ATPase FliI VFG0730 Protein 8e-76 45
TK90_1161 YP_003460406.1 flagellar protein export ATPase FliI VFG0515 Protein 9e-75 44
TK90_1161 YP_003460406.1 flagellar protein export ATPase FliI VFG2144 Protein 1e-84 44
TK90_1161 YP_003460406.1 flagellar protein export ATPase FliI VFG0048 Protein 5e-84 44
TK90_1161 YP_003460406.1 flagellar protein export ATPase FliI VFG0390 Protein 3e-75 44
TK90_1161 YP_003460406.1 flagellar protein export ATPase FliI VFG0192 Protein 3e-78 42
TK90_1161 YP_003460406.1 flagellar protein export ATPase FliI VFG2459 Protein 8e-67 42
TK90_1161 YP_003460406.1 flagellar protein export ATPase FliI VFG0555 Protein 4e-63 42