Gene Information

Name : guaA (LLO_2251)
Accession : YP_003455717.1
Strain : Legionella longbeachae NSW150
Genome accession: NC_013861
Putative virulence/resistance : Unknown
Product : GMP synthetase (glutamine-hydrolyzing)
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : 6.3.5.2
Position : 2631671 - 2633248 bp
Length : 1578 bp
Strand : -
Note : equals llo2251; similar to GMP synthetase (glutamine-hydrolyzing)

DNA sequence :
ATGAAAGATTTAAAACAGCATCCTTTGTTAATCCTTGACTTCGGTTCTCAATATACACAACTGATTGCACGACGTGTTCG
TGAACTAGGTGTGTATTGTGAAATTCATCCTTTTAATATTAAACAAGAAAAATTTATTGCACTAAATCCATGCGGTGTGA
TTTTATCCGGGGGCCCCGCAACAGTAACCTATGATACAAACCCGCGTGCGCCTGAATGGTTATTTACTACCGGAATACCT
ATTTTAGGAATTTGCTATGGAATGCAAACAATGGCAGTTCAATTGGGAGGGGAGGTCCAATCTTCTTCATTGAGAGAGTT
TGGTTATGCAGAATTAAAATTACATGGACACAGCCAATTGTTTTCGCAAATCGAAGATCGTATCAGTTCTGAGGGGGGGG
CTTTATTAGATGTCTGGATGAGTCATGGAGATAAGGTAACGCAACTACCACCAGGTTTTAAAATTATTTGTGAAACTCGC
AATGCCCCTATTGCTGGGATGGCAGATGAAAGTCGTCAAATGTATGGGGTGCAGTTTCATCCAGAAGTAACACATACTTT
GCAAGGAATGCGAATTTTACATCGTTTTGTGGTGGATATTTGCAAGGCTGCGACCAATTGGACTTCTGAGCTTATTATTG
ATGAGGCGATTAGTGAGATAAGGGCTCAAGTAGGAACAGAGAAAGTCCTACTGGGATTATCTGGGGGGGTAGATTCTTCA
GTTGTAGCTGCTTTATTGCACAAAGCAATTGGAAAGCAATTGATTTGTGTTTTTGTGGATACAGGCTTATTACGTATTCA
TGAGGCAGATGAAGTGATGAATATGTTTGGCAAAAACATGGGAATACAAGTTATTGCTGTGAAAGCTGAAGATAAATTTT
TAAATGCATTGAAAGGCGTCACCTGCCCTGAAGAAAAACGCAAAATTATCGGCCATACCTTTATTGAGGTATTTGATGAA
GAAGCCCACAAAATTCCTGGCGTTTCATGGCTGGCTCAAGGGACCATTTATCCTGATGTCATTGAGTCTGCTGCAACAAA
TACAAATGGGGCTTCAATGGTTATTAAATCGCACCATAACGTAGGTGGGTTGCCTGAAACCTTAAATTTGAAATTATTAG
AACCTATACGTGAATTATTTAAAGATGAAGTTCGTAATATAGGTCTTGAGCTGGGTTTACCTCATGATATGATCCATCGT
CATCCATTTCCAGGACCTGGTTTAGGAGTGCGAATTTTAGCTGAAGTGAAAAAGGAGTATGCTGATATTTTACGTAAGGC
AGATGCCATTTTCATCGATGAATTGAGAAAAGCTGATCTTTATTATAAGGTGAGCCAGGCATTTGCCGTATTTTTACCCG
TTAAAAGTGTGGGAGTGATGGGAGATGGTCGTAAATATGATTATGTCGTTTGTCTCCGTGCTGTAGAAACAATTGATTTT
ATGACCGCACATTGGGCTCACTTACCGTGGGACTTTCTTGGCCAAGTCTCTAATCGTATTATAAATGAAGTAGAAGGTGT
TTCACGTGTTACTTATGATATCTCGGGCAAACCGCCAGCTACTATTGAATGGGAATGA

Protein sequence :
MKDLKQHPLLILDFGSQYTQLIARRVRELGVYCEIHPFNIKQEKFIALNPCGVILSGGPATVTYDTNPRAPEWLFTTGIP
ILGICYGMQTMAVQLGGEVQSSSLREFGYAELKLHGHSQLFSQIEDRISSEGGALLDVWMSHGDKVTQLPPGFKIICETR
NAPIAGMADESRQMYGVQFHPEVTHTLQGMRILHRFVVDICKAATNWTSELIIDEAISEIRAQVGTEKVLLGLSGGVDSS
VVAALLHKAIGKQLICVFVDTGLLRIHEADEVMNMFGKNMGIQVIAVKAEDKFLNALKGVTCPEEKRKIIGHTFIEVFDE
EAHKIPGVSWLAQGTIYPDVIESAATNTNGASMVIKSHHNVGGLPETLNLKLLEPIRELFKDEVRNIGLELGLPHDMIHR
HPFPGPGLGVRILAEVKKEYADILRKADAIFIDELRKADLYYKVSQAFAVFLPVKSVGVMGDGRKYDYVVCLRAVETIDF
MTAHWAHLPWDFLGQVSNRIINEVEGVSRVTYDISGKPPATIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 2e-123 50
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 2e-123 50
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 2e-123 50
guaA NP_938969.1 GMP synthase Not tested Not named Protein 2e-110 47