Gene Information

Name : clpE (smi_0865)
Accession : YP_003445981.1
Strain : Streptococcus mitis B6
Genome accession: NC_013853
Putative virulence/resistance : Virulence
Product : ATP-dependent Clp protease, ATP-binding subunit
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0542
EC number : -
Position : 820713 - 822971 bp
Length : 2259 bp
Strand : -
Note : -

DNA sequence :
ATGCTTTGTCAAAACTGTAAAATCAACGACTCAACAATTCATCTTTACACCAATCTCAATGGAAAACAAAAACAAATTGA
CCTCTGTCAAAACTGCTACAAGATTATCAAAACAGATCCTAACAATAGCCTCTTTAAAGGTATGACAGATCTGAACAATC
GTGACTTTGATCCTTTTGGGGATTTCTTCAATGATCTAAACAATTTCAGACCTTCTAACAACACTCCTCCTACTCCCCCA
ACCCAATCAGGTGGAGGTTACGGTGGAAACGGCGGTTATGGTTCCCAAAATCGTGGACCTGCTCAAACTCCTCCACCAAG
CCAAGAAAAAGGCCTGCTGGAAGAATTTGGTATCAACATAACTGAAATTGCCCGTCGTGGCGATATTGACCCCGTTATTG
GGCGCGATGATGAGATTATCCGTGTCATCGAAATTCTCAATCGTAGAACTAAGAATAATCCTGTTCTTATCGGTGAACCA
GGTGTCGGGAAAACGGCTGTTGTCGAAGGTCTAGCTCAGAAAATCGTTGATGGAGATGTTCCACATAAACTCCAAGGTAA
ACAAGTCATCCGTCTGGATGTGGTTAGCTTGGTTCAAGGAACGGGTATCCGAGGACAATTTGAAGAACGCATGCAAAAAC
TCATGGAAGAAATTCGCAAACGTGAAGACATTATTCTCTTTATAGATGAAATCCATGAAATTGTCGGTGCAGGTTCTGCT
GGCGATGGCAATATGGATGCAGGAAATATCCTCAAGCCAGCCCTTGCTCGTGGGGAACTGCAACTGGTCGGTGCCACTAC
CCTCAATGAATACCGTATCATTGAAAAGGATGCCGCCCTAGAGCGTCGTATGCAACCTGTTAAGGTCGATGAACCAACTG
TGGAAGAAACAATCACTATCCTCAAAGGAATTCAAAAGAAATACGAAGACTACCACCACGTTCAGTATACCGATGCTGCT
ATCGAAGCAGCTGCAACTCTTTCCAATCGTTACATCCAAGATCGCTTCTTGCCTGACAAGGCCATTGACCTCCTAGATGA
AGCTGGTTCTAAGATGAACTTGACCCTGAATTTTGTAGATCCTAAAGTGATTGACCAGCGCTTGATTGAGGCTGAAAATC
TCAAATCTCAAGCTACACGAGAGGAAGATTTTGAGAAGGCCGCCTACTTCCGTGACCAGATTGCCAAGTATAAGGAAATG
CAAAAGAAAAAGGTCACAGACCAGGACACTCCTATCATCAGTGAGAAAACCATTGAGCACATTATCGAGCAGAAAACCAA
CATTCCTGTTGGCGATTTGAAAGAGAAAGAACAATCTCAACTCATCCATCTAGCCGAAGATCTCAAGTCTCATGTCATTG
GACAAGATGATGCTGTCGATAAGATTGCCAAGGCTATTCGCCGGAATCGTGTCGGTCTCGGTACGCCTAACCGCCCAATC
GGAAGCTTCCTCTTTGTCGGACCAACTGGGGTCGGTAAGACAGAACTTTCCAAACAATTAGCTATCGAACTCTTTGGTTC
TGCTGATAGCATGATTCGCTTTGACATGAGCGAATACATGGAAAAACACAGCGTAGCTAAGTTGGTCGGCGCCCCTCCAG
GTTATGTTGGCTACGATGAGGCTGGGCAATTAACTGAAAAAGTTCGTCGCAATCCATATTCTCTTATTCTCTTGGATGAA
GTAGAGAAAGCCCATCCAGATGTTATGCATATGTTCCTACAAGTCTTGGACGATGGTCGTTTGACAGATGGGCAAGGACG
TACCGTTAGCTTCAAGGATGCCATCATTATCATGACTTCAAATGCAGGGACAGGTAAGGCCGAAGCCAGCGTTGGTTTCG
GGGCAGCTCGCGAAGGACGGACCAACTCTGTTCTCGGTGAACTCGGCAACTTCTTTAGCCCAGAGTTTATGAACCGTTTT
GATGGTATTATCGAATTTAAGGCTCTCAGCAAGGATAACCTCCTTCAGATTGTCGAGCTTATGCTATCAGACGTTAACAA
GCGCCTTTCTAGCAACAACATTCATTTAGATGTAACTGAAAAGGTCAAGGAAAAATTGGTTGACCTCGGTTATGATCCAA
AAATGGGAGCACGCCCACTTCGTCGTACTATTCAAGACTATATTGAGGACGCAATCACTGACTTCTACCTTGAAAATCCA
AGCGAAAAAGACCTCAAGGCAGTTATGACCAGCAAGGGCAAGATTCAAATTAAGTCTGCCAAAAAAGCTGAAGTAAAAAC
TTCTGAAAAAGAAGTATAA

Protein sequence :
MLCQNCKINDSTIHLYTNLNGKQKQIDLCQNCYKIIKTDPNNSLFKGMTDLNNRDFDPFGDFFNDLNNFRPSNNTPPTPP
TQSGGGYGGNGGYGSQNRGPAQTPPPSQEKGLLEEFGINITEIARRGDIDPVIGRDDEIIRVIEILNRRTKNNPVLIGEP
GVGKTAVVEGLAQKIVDGDVPHKLQGKQVIRLDVVSLVQGTGIRGQFEERMQKLMEEIRKREDIILFIDEIHEIVGAGSA
GDGNMDAGNILKPALARGELQLVGATTLNEYRIIEKDAALERRMQPVKVDEPTVEETITILKGIQKKYEDYHHVQYTDAA
IEAAATLSNRYIQDRFLPDKAIDLLDEAGSKMNLTLNFVDPKVIDQRLIEAENLKSQATREEDFEKAAYFRDQIAKYKEM
QKKKVTDQDTPIISEKTIEHIIEQKTNIPVGDLKEKEQSQLIHLAEDLKSHVIGQDDAVDKIAKAIRRNRVGLGTPNRPI
GSFLFVGPTGVGKTELSKQLAIELFGSADSMIRFDMSEYMEKHSVAKLVGAPPGYVGYDEAGQLTEKVRRNPYSLILLDE
VEKAHPDVMHMFLQVLDDGRLTDGQGRTVSFKDAIIIMTSNAGTGKAEASVGFGAAREGRTNSVLGELGNFFSPEFMNRF
DGIIEFKALSKDNLLQIVELMLSDVNKRLSSNNIHLDVTEKVKEKLVDLGYDPKMGARPLRRTIQDYIEDAITDFYLENP
SEKDLKAVMTSKGKIQIKSAKKAEVKTSEKEV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
clpC YP_005163377.1 ATP-dependent Clp protease ATP-binding subunit Not tested Not named Protein 3e-153 52

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
clpE YP_003445981.1 ATP-dependent Clp protease, ATP-binding subunit VFG0080 Protein 0.0 58
clpE YP_003445981.1 ATP-dependent Clp protease, ATP-binding subunit VFG0079 Protein 3e-161 54