Gene Information

Name : clpC (smi_2045)
Accession : YP_003447141.1
Strain : Streptococcus mitis B6
Genome accession: NC_013853
Putative virulence/resistance : Virulence
Product : ATP-dependent Clp protease, ATP-binding subunit
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0542
EC number : -
Position : 2101481 - 2103913 bp
Length : 2433 bp
Strand : -
Note : COG0542, ClpA, ATPases with chaperone activity, ATP-binding subunit

DNA sequence :
ATGAACTATTCAAAAGCATTGAATGAATGTATCGAAAGTGCCTACATGGTTGCTGGCCATTTTGGAGCTCGTTACCTAGA
GTCTTGGCACTTGTTGATTGCCATGTCCAATCACAGTTATAGTGTGGCAGGGGCAACTTTAAATGATTATCCATATGAGA
TGGACCGTTTAGAAGAGGTCGCTTTGGAACTGACTGAAACGAACTATAGCCAGGATGAAACCTTTACGGAATTGCCGTTT
TCTCATCGTTTGCAGGTTCTTTTTGACGAAGCAGAGTATGTAGCGTCAGTGGTCCATGCTAAGATGCTAGGGACGGAGCA
CGTCCTTTATGCGATTTTGCATGATGGAAATGCCTTGGCGACTCGTATTTTGGAGAGGGCTGGTTTTTCTTATGAAGACA
AGAAAGATCAGGTCAAGATTGCTGCTCTTCGTCGAAATTTAGAAGAACGGGCAGGCTGGACCCGTGAAGACCTCAAGGCT
TTACGCCAACGCCATCGTACAGTAGCTGATAAGCAAAATTCTATGGCTAATATGATGGGCATGCCCCAGACTCCGAGTGG
TGGTCTCGAGGACTATACGCATGATTTGACAGAGCAAGCGCGTTCTGGCAAGTTAGAACCAGTCATTGGTCGAGATAAGG
AAATCTCGCGTATGATTCAAATCTTGAGCCGTAAGACCAAGAATAATCCTGTCTTGGTTGGAGATGCTGGTGTTGGGAAA
ACTGCTCTGGCGCTTGGTCTTGCCCAGCGTATTGCTAGTGGGGATGTGCCTGCGGAAATGGCTAAGATGCGCGTGTTGGA
GCTGGATTTGATGAATGTCGTTGCAGGGACACGTTTTCGTGGTGACTTTGAAGAACGCATGAACAATATCATCAAGGATA
TTGAGGAAGATGGGCAAGTCATCCTCTTTATCGATGAACTTCATACCATCATGGGTTCTGGGAGCGGGATTGACTCAACT
CTGGATGCGGCCAATATCTTGAAACCAGCCTTGGCGCGTGGTACCTTGAGAACGGTTGGCGCGACCACTCAGGAGGAATA
CCAAAAACATATCGAAAAAGATGCGGCCCTTTCTCGTCGTTTCGCCAAAGTAACGATTGAAGAGCCAAGCGTGGCCGACA
GTATGGCGATTTTGCAAGGTTTGAAGGTGACTTATGAGAAACACCACCGTGTGCAAATCACAGATGAAGCGGTTGAAACA
GCCGTTAAGATGGCCCATCGTTACTTGACTAGTCGCCATTTGCCAGACTCTGCTATCGATCTCTTGGATGAGGCAGCAGC
AACAGTGCAAAATAAGGCTAAGCATGTAAAAGCAGACGATTCAGGTTTGAGTCCAGCTGACAAGGCCTTGATGGATGGTA
AGTGGAAACAAGCTACTCAACTAATTGCTAAAGAAGAGGAAGTGCCTGTCTATAAAGACTTGGTGACGGAGTCTGATATT
TTGACCACCTTGAGTCGCTTGTCAGGCATTCCAGTCCAAAAACTGACTCAGACTGATGCGAAGAAATACCTGAATCTGGA
AGCTGAATTGCACAAACGTGTCATCGGTCAAGATCAAGCTGTTTCAAGCATTAGCCGTGCGATTCGCCGCAACCAGTCAG
GGATTCGCAGTCACAAGCGTCCGATTGGTTCCTTTATGTTCCTAGGACCTACAGGTGTCGGTAAGACCGAATTGGCCAAG
GCTCTGGCGGAAGTTCTCTTTGATGACGAATCAGCTCTTATCCGCTTTGATATGAGTGAGTATATGGAGAAATTTGCAGC
CAGCCGTCTCAATGGAGCTCCTCCGGGCTATGTGGGCTACGAAGAAGGTGGGGAGTTGACCGAGAAAGTTCGCAACAAAC
CATACTCTGTTCTCCTCTTTGACGAGGTAGAGAAGGCCCATCCAGATATCTTTAATGTTCTCTTGCAGGTCTTGGATGAT
GGTGTCTTGACCGATAGCAAGGGCCGCAAGGTTGACTTTTCAAATACCATTATTATCATGACGTCAAATCTTGGTGCGAC
AGCTCTTCGTGATGACAAGACAGTTGGTTTTGGGGCTAAGGACATTCGTTTTGACCAGGAAAATATGGAAAAACGCATGT
TTGAAGAGCTGAAAAAAGCTTATAGACCTGAGTTTATTAACCGTATTGATGAGAAGGTGGTCTTCCATAGCCTTTCTAGC
GACCATATGCAGGAAGTAGTGAAGATTATGGTCAGACCTTTAGTGGCAAGTTTGGCTGAAAAAGGTATTGACTTGAAATT
ACAAGCTTCCGCACTGAAATTGTTGGCCAATCAAGGATATGACCCAGAGATGGGAGCTCGTCCACTTCGCAGAACCCTGC
AAACAGAAGTGGAAGACAAGTTAGCAGAACTTCTTCTCAAGGGAGATTTAGTGGCAGGCAACACACTTAAGATTGGTATC
AAAGCAGGCCAGTTAAAATTTGATATTGTATAA

Protein sequence :
MNYSKALNECIESAYMVAGHFGARYLESWHLLIAMSNHSYSVAGATLNDYPYEMDRLEEVALELTETNYSQDETFTELPF
SHRLQVLFDEAEYVASVVHAKMLGTEHVLYAILHDGNALATRILERAGFSYEDKKDQVKIAALRRNLEERAGWTREDLKA
LRQRHRTVADKQNSMANMMGMPQTPSGGLEDYTHDLTEQARSGKLEPVIGRDKEISRMIQILSRKTKNNPVLVGDAGVGK
TALALGLAQRIASGDVPAEMAKMRVLELDLMNVVAGTRFRGDFEERMNNIIKDIEEDGQVILFIDELHTIMGSGSGIDST
LDAANILKPALARGTLRTVGATTQEEYQKHIEKDAALSRRFAKVTIEEPSVADSMAILQGLKVTYEKHHRVQITDEAVET
AVKMAHRYLTSRHLPDSAIDLLDEAAATVQNKAKHVKADDSGLSPADKALMDGKWKQATQLIAKEEEVPVYKDLVTESDI
LTTLSRLSGIPVQKLTQTDAKKYLNLEAELHKRVIGQDQAVSSISRAIRRNQSGIRSHKRPIGSFMFLGPTGVGKTELAK
ALAEVLFDDESALIRFDMSEYMEKFAASRLNGAPPGYVGYEEGGELTEKVRNKPYSVLLFDEVEKAHPDIFNVLLQVLDD
GVLTDSKGRKVDFSNTIIIMTSNLGATALRDDKTVGFGAKDIRFDQENMEKRMFEELKKAYRPEFINRIDEKVVFHSLSS
DHMQEVVKIMVRPLVASLAEKGIDLKLQASALKLLANQGYDPEMGARPLRRTLQTEVEDKLAELLLKGDLVAGNTLKIGI
KAGQLKFDIV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
clpC YP_005163377.1 ATP-dependent Clp protease ATP-binding subunit Not tested Not named Protein 1e-140 49

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
clpC YP_003447141.1 ATP-dependent Clp protease, ATP-binding subunit VFG0079 Protein 4e-161 47
clpC YP_003447141.1 ATP-dependent Clp protease, ATP-binding subunit VFG0080 Protein 5e-125 43