Gene Information

Name : clpL (smi_1765)
Accession : YP_003446864.1
Strain : Streptococcus mitis B6
Genome accession: NC_013853
Putative virulence/resistance : Virulence
Product : ATP-dependent Clp protease, ATP-binding subunit
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0542
EC number : -
Position : 1824278 - 1826383 bp
Length : 2106 bp
Strand : -
Note : COG0542

DNA sequence :
ATGAACAACAACTTTAATAATTTTAATAACATGGATGATTTATTTAACCAATTGATGGGGGGGATGCGAGGATATAGTTC
TGAAAATCGTCGCTACTTGATTAATGGACGTGAAGTGACACCTGAGGAATTTGCTCATTATCGTGCAACTGGTCAATTGC
CAGGAAATGCAGAAGCTGATGGACAAATGAAACAACCGGCATCAGGTATGAAACAAGACGGTGTCCTTGCTAAACTAGGT
CGAAACTTGACAGCAGAAGCTCGCGAGGGCAAGTTGGATCCTGTTATCGGACGAAACGAGGAAATTCAAGAAACATCTGA
AATCCTCTCACGTCGTACCAAGAATAATCCTGTTTTGGTCGGAGATGCAGGTGTTGGTAAGACAGCTGTTGTCGAAGGTC
TAGCACAGGCGATTGTGAACGGTGATGTTCCAGCTGCCATTAAGAATAAAGAAATTATTTCCATCGATATCTCAGGTCTC
GAGGCTGGTACTCAATACCGTGGTAGCTTTGAAGAAAACGTTCAAAATCTAGTCAATGAAGTGAAAGAAGCGGGAAATAT
CATTCTCTTCTTTGATGAAATTCATCAAATTCTCGGTGCTGGTAGCACTGGTGGAGATAGTGGATCTAAGGGACTTGCAG
ACATTCTTAAACCAGCTCTATCTCGTGGAGAATTGACAGTGATTGGGGCAACGACTCAAGACGAATACCGTAACACCATT
TTGAAGAATGCAGCTCTTGCTCGTCGTTTCAATGAAGTCAAGGTCAATGCTCCTTCAGCAGAGGATACATATAAAATTCT
TCAAGGAATTCGTGACCTCTATCAACAACACCACAATGTCATCTTGCCAGATGAAGTTTTGAAAGCGGCGGTGGATTATT
CTGTTCAGTATATTCCTCAACGTAGCTTGCCAGATAAGGCTATCGACCTTGTCGATGTTACGGCAGCTCACTTGGCAGCA
CAACATCCAGTAACAGATGTTCATGCTGTTGAACGTGAAATTGAGGCAGAAAAAGACAAGCAAGAAAAAGCAGTTGAGGC
AGAAGATTTTGAAGCAGCTCTAAACTATAAAACACGCATCGCAGAATTGGAAAAGAAAATCGAAAACCACACAGAAGATA
TGAAGGTGACTGCAAGTGTCAACGATGTGGCTGAGTCTGTAGAACGAATGACCGGTATTCCAGTGTCACAAATGGGAGCA
TCAGACATCGAACGTCTGAAAGATATGGCTCATCGTCTGCAAGATAAGGTAATCGGTCAAGATAAGGCAGTTGAAGCTGT
AGCCCGTGCTATCCGTCGTAACCGTGCTGGTTTTGATGAAGGTAATCGCCCAATTGGTAGCTTCCTCTTTGTAGGTCCAA
CTGGAGTTGGTAAGACTGAACTTGCTAAACAATTGGCGCTAGATATGTTTGGAACTAAGGACGCAATCATCCGTTTGGAT
ATGTCTGAATACAGTGATCGAACAGCCGTTTCTAAGCTAATTGGTACAACAGCAGGATATGTGGGTTATGATGACAATAG
CAATACCTTAACAGAACGTGTTCGTCGCAATCCATACTCTATCATTCTCTTGGATGAAATTGAAAAGGCTGATCCTCAAG
TCATTACCCTTCTCCTCCAAGTTCTAGATGATGGTCGTTTGACAGATGGTCAAGGAAATACAGTAAACTTCAAGAACACT
GTCATTATCGCGACCTCAAATGCTGGATTTGGCTATGAAGCTAACTTGACAGAGGATGCGGATAAGCCAGAATTGATGGA
CCGTTTGAAGCCATTCTTCCGTCCAGAATTCCTCAACCGCTTTAATGCAGTTATCGAGTTCTCACACTTGACTAAGGAAG
ATCTTTCTAAGATTGTGGACTTGATGTTGGCTGAAGTTAACCATACCTTGGCTAAGAAAGACATTGATTTGGTAGTCAGT
CAAGCAGCTAAGGACTATATCACAGAAGAAGGTTATGACGAAGTCATGGGTGTTCGTCCACTCCGTCGCGTGGTTGAACA
AGAAATTCGTGATAAGGTGACAGACTTCCATTTGGATCACCTAGATGCCAAACACCTAGAAGCAGATATGGAAGATGGTG
TTTTGGTTATTCGTGAAAAAGCCTAA

Protein sequence :
MNNNFNNFNNMDDLFNQLMGGMRGYSSENRRYLINGREVTPEEFAHYRATGQLPGNAEADGQMKQPASGMKQDGVLAKLG
RNLTAEAREGKLDPVIGRNEEIQETSEILSRRTKNNPVLVGDAGVGKTAVVEGLAQAIVNGDVPAAIKNKEIISIDISGL
EAGTQYRGSFEENVQNLVNEVKEAGNIILFFDEIHQILGAGSTGGDSGSKGLADILKPALSRGELTVIGATTQDEYRNTI
LKNAALARRFNEVKVNAPSAEDTYKILQGIRDLYQQHHNVILPDEVLKAAVDYSVQYIPQRSLPDKAIDLVDVTAAHLAA
QHPVTDVHAVEREIEAEKDKQEKAVEAEDFEAALNYKTRIAELEKKIENHTEDMKVTASVNDVAESVERMTGIPVSQMGA
SDIERLKDMAHRLQDKVIGQDKAVEAVARAIRRNRAGFDEGNRPIGSFLFVGPTGVGKTELAKQLALDMFGTKDAIIRLD
MSEYSDRTAVSKLIGTTAGYVGYDDNSNTLTERVRRNPYSIILLDEIEKADPQVITLLLQVLDDGRLTDGQGNTVNFKNT
VIIATSNAGFGYEANLTEDADKPELMDRLKPFFRPEFLNRFNAVIEFSHLTKEDLSKIVDLMLAEVNHTLAKKDIDLVVS
QAAKDYITEEGYDEVMGVRPLRRVVEQEIRDKVTDFHLDHLDAKHLEADMEDGVLVIREKA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
clpC YP_005163377.1 ATP-dependent Clp protease ATP-binding subunit Not tested Not named Protein 2e-137 47

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
clpL YP_003446864.1 ATP-dependent Clp protease, ATP-binding subunit VFG0080 Protein 1e-146 48
clpL YP_003446864.1 ATP-dependent Clp protease, ATP-binding subunit VFG0079 Protein 1e-142 45