Gene Information

Name : aadE (smi_1710)
Accession : YP_003446812.1
Strain : Streptococcus mitis B6
Genome accession: NC_013853
Putative virulence/resistance : Resistance
Product : streptomycin aminoglycoside 6-adenyltransferase
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 1762050 - 1762958 bp
Length : 909 bp
Strand : -
Note : -

DNA sequence :
ATGAGATCAGAAAAAGAAATGATGGATTTAGTACTTTCTTTAGCAGAACAGGATGAACGTATTCGAATTGTGACCCTTGA
GGGGTCACGCGCAAATATTAATATACCTAAAGATGAATTTCAGGATTATGATATTACATATTTTGTAAGTGATATAGAAC
CGTTTATATCTAATGATGACTGGCTTAATCAATTTGGGAATATTATAATGATGCAAAAACCGGAGGATATGGAACTATTC
CCGGCTGAAGAGAAAGGCTACTCCTATATAATACTTTTTGATGATTATAATAAAATAGACCTTACCTTATTGCCCCTGGA
AGAGTTGGGAAACTACCTGAATGACGATAAATTGATAAAGATTATTCTGGATAAGGATGGAAGGATTCAGCAAGCTGTAG
TTCCGACCGACATGGATTATCATATAAGAAAACCCAGTGCCCGGGAATACGATGACTGCTGCAATGAATTCTGGAACACC
ACTACCTATGTGGTTAAGGGACTGTGCCGTAAGGAAATTTTATTTGCTATTGATCATTTTAATCAGATTGTTCGCCATGA
GCTGCTGAGAATGATATCATGGAAGGTCGGCATCGAAACAGGCTTTAAATTAAGTGTAGGCAAGAACTATAAGTTTATTG
AAAGGTATATATCCGAGGATTTGTGGGAGAAACTTTTGTCCACCTACCGGATGGATTCCTATGAAAACATATGGGAAGCA
TTATTTCTATGCCATCAATTGTTCAGGGCGGTATCCGGTGAGGTGGCGGAAAGGCTTCATTATGCCTATCCGGAGTATGA
TAGGAATATAACAAAATATACCAGGGACATGTATAAAAAATACACTGGTAAAACCGGCTGCCTGGATAGCACATATGCCG
CTGATATAGAAGAGAGGCGGGAACAGTGA

Protein sequence :
MRSEKEMMDLVLSLAEQDERIRIVTLEGSRANINIPKDEFQDYDITYFVSDIEPFISNDDWLNQFGNIIMMQKPEDMELF
PAEEKGYSYIILFDDYNKIDLTLLPLEELGNYLNDDKLIKIILDKDGRIQQAVVPTDMDYHIRKPSAREYDDCCNEFWNT
TTYVVKGLCRKEILFAIDHFNQIVRHELLRMISWKVGIETGFKLSVGKNYKFIERYISEDLWEKLLSTYRMDSYENIWEA
LFLCHQLFRAVSGEVAERLHYAYPEYDRNITKYTRDMYKKYTGKTGCLDSTYAADIEERREQ

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
aadE YP_003446812.1 streptomycin aminoglycoside 6-adenyltransferase Not tested The aminoglycoside resistance gene cluster Protein 9e-132 100
aadE AFJ97257.1 streptomycin aminoglycoside 6-adenyltransferase Not tested Not named Protein 1e-91 90
SSU05_0957 YP_001198323.1 aminoglycoside 6-adenylyltansferase Not tested 89K Protein 2e-107 83
SSU98_0964 YP_001200522.1 aminoglycoside 6-adenylyltansferase Not tested 89K Protein 2e-107 83
aadE AFJ97264.1 putative adenyltransferase Not tested Not named Protein 2e-82 64

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
aadE YP_003446812.1 streptomycin aminoglycoside 6-adenyltransferase NC_006663.1.orf0.gen Protein 1e-116 93
aadE YP_003446812.1 streptomycin aminoglycoside 6-adenyltransferase AJ489618.1.orf2.gene Protein 3e-93 88
aadE YP_003446812.1 streptomycin aminoglycoside 6-adenyltransferase FN594949.1.gene25.p0 Protein 1e-83 64