Gene Information

Name : Kvar_0761 (Kvar_0761)
Accession : YP_003437703.1
Strain : Klebsiella variicola At-22
Genome accession: NC_013850
Putative virulence/resistance : Resistance
Product : arsenical pump membrane protein
Function : -
COG functional category : P : Inorganic ion transport and metabolism
COG ID : COG1055
EC number : -
Position : 792957 - 794249 bp
Length : 1293 bp
Strand : +
Note : TIGRFAM: arsenical pump membrane protein; PFAM: Arsenical pump membrane protein; KEGG: kpe:KPK_0800 arsenical pump membrane protein

DNA sequence :
ATGTTGCTGGCAGGCGCGATTTTTGTCCTGACCCTGGTGTTGGTGATCTGGCAGCCGCGGGGTTTAGGGATCGGCTGGAG
CGCGGCCTTTGGCGCGGCGCTGGCGCTGGCCACCGGTGGAGTACAACTAGCCGATATCCCGGTGGTGTGGCATATCGTCT
GGAATGCGACCGCCACCTTTATCGCCGTTATCATTATCAGCCTGCTGCTTGATGAGTCTGGCTTTTTTGAATGGGCCGCG
CTGCACGTTTCCCGCTGGGGAAGAGGGCGGGGTCGTCTGCTATTTACCTGGATTATCCTGCTCGGCGCCGCGGTGGCGGC
GCTGTTTGCCAACGACGGCGCGGCGCTGATCCTCACCCCCATCGTGATTGCCATGCTGCGAGCGCTGGGATTCAGCAAGG
GAACGATGCTGGCCTTTGTCATGGCCGCCGGATTTATTGCCGATACCGCTAGCCTGCCGCTGGTGGTGTCGAATCTGGTG
AATATCGTTTCGGCAGATTTCTTTGCCATCGGCTTCAGGGAGTACGCTTCGGTGATGGTGACGGTCGATCTCGCGGCGAT
CCTCACCACCCTGGCGATGCTGCACCTGTTCTTTCGCCGGGATATCCCGCCGGCCTGGGATATGGCGTTACTGAAAGCGC
CGGTCACGGCGATAAAAGATCCGGCGACGTTCCGCACCGGCTGGGGCGTGCTGCTGCTGTTGCTGGTCGGCTTTTTCGTT
CTTGACCCGCTGGGGATCCCGGTCAGCGCCATCGCGGCGCCGGGAGCGGGGATCCTGTTTGCTGTCGCGAAGCGCGGGCG
GGTGATTAACACCGGCAAGGTGCTGCGCGGCGCCCCGTGGCAGATCGTGATCTTCTCGCTGGGAATGTATCTGGTGGTGT
ATGGCCTGCGAAACGCCGGGTTAACGGATTATCTGACCACGGTGCTGAACATGCTGGCGGAGCGCGGGCTCTGGGCCGCG
ACGCTGGGCACCGGTATCCTGTCGGCCTTCCTCTCTTCAATAATGAATAATATGCCCAGCGTACTGGTCGGCGCCCTGTC
GATTGATGGCAGCGCGGCAACAGGGACGATCAAAGAGGCCATGATTTATGCCAACGTCATCGGCTGCGATCTGGGGCCCA
AGATCACGCCAATTGGTAGCCTGGCCACGCTGCTCTGGCTGCATGTGCTGGCGCAGAAGCACATCACCATCGGTTGGGGG
TATTATTTCCGCTGCGGCATTACCATGACCCTGCCGGTGCTGCTTGTGACGCTGGCCGCGCTGGCGCTGCGTCTCTCCTT
CAACCAGCCATGA

Protein sequence :
MLLAGAIFVLTLVLVIWQPRGLGIGWSAAFGAALALATGGVQLADIPVVWHIVWNATATFIAVIIISLLLDESGFFEWAA
LHVSRWGRGRGRLLFTWIILLGAAVAALFANDGAALILTPIVIAMLRALGFSKGTMLAFVMAAGFIADTASLPLVVSNLV
NIVSADFFAIGFREYASVMVTVDLAAILTTLAMLHLFFRRDIPPAWDMALLKAPVTAIKDPATFRTGWGVLLLLLVGFFV
LDPLGIPVSAIAAPGAGILFAVAKRGRVINTGKVLRGAPWQIVIFSLGMYLVVYGLRNAGLTDYLTTVLNMLAERGLWAA
TLGTGILSAFLSSIMNNMPSVLVGALSIDGSAATGTIKEAMIYANVIGCDLGPKITPIGSLATLLWLHVLAQKHITIGWG
YYFRCGITMTLPVLLVTLAALALRLSFNQP

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
arsB2 YP_001007633.1 arsenical pump membrane protein Not tested YAPI Protein 5e-149 85
arsB YP_252017.1 arsenical pump membrane protein Not tested SCCmec Protein 4e-98 58
arsB YP_005754065.1 arsenical pump membrane protein Not tested Type-XI SCCmec Protein 3e-96 56
SH0109 YP_252024.1 arsenical pump membrane protein Not tested SCCmec Protein 2e-98 56

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Kvar_0761 YP_003437703.1 arsenical pump membrane protein BAC0578 Protein 9e-151 86
Kvar_0761 YP_003437703.1 arsenical pump membrane protein BAC0576 Protein 8e-150 86
Kvar_0761 YP_003437703.1 arsenical pump membrane protein BAC0031 Protein 7e-149 85
Kvar_0761 YP_003437703.1 arsenical pump membrane protein BAC0577 Protein 6e-148 83
Kvar_0761 YP_003437703.1 arsenical pump membrane protein BAC0574 Protein 3e-97 57
Kvar_0761 YP_003437703.1 arsenical pump membrane protein BAC0575 Protein 4e-99 56