Gene Information

Name : Kvar_0628 (Kvar_0628)
Accession : YP_003437570.1
Strain : Klebsiella variicola At-22
Genome accession: NC_013850
Putative virulence/resistance : Virulence
Product : urease subunit alpha
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0804
EC number : 3.5.1.5
Position : 657248 - 658951 bp
Length : 1704 bp
Strand : -
Note : KEGG: kpe:KPK_0652 urease subunit alpha; TIGRFAM: urease subunit alpha; PFAM: amidohydrolase; Urease alpha-subunit domain protein

DNA sequence :
ATGAGTAATATTTCACGCCAGGCCTATGCCGATATGTTCGGCCCCACCGTCGGCGACAAGGTGCGCCTGGCCGATACCGA
GCTGTGGATCGAGGTGGAAGATGATTTGACCACCTACGGAGAAGAGGTCAAATTCGGCGGCGGCAAAGTGATCCGCGACG
GGATGGGTCAGGGACAGATGCTGGCCGCCGACTGTGTCGACCTGGTGCTCACCAACGCGCTGATCGTTGATCACTGGGGG
ATCGTCAAGGCCGATATCGGCGTGAAGGACGGCCGGATCTTCGCCATCGGCAAAGCCGGCAATCCCGATATCCAGCCCAA
CGTCACCATCCCCATCGGCGCCGCGACGGAAGTGATTGCCGCCGAAGGCAAGATCGTCACCGCCGGCGGGATCGATACCC
ATATTCACTGGATCTGTCCGCAACAGGCGGAAGAGGCGCTGGTCTCCGGCGTGACCACCATGGTCGGCGGCGGCACCGGC
CCGGCCGCGGGCACCCATGCCACCACCTGCACCCCGGGCCCCTGGTATATCTCACGCATGCTGCAAGCGGCCGACAGCCT
GCCGGTCAATATCGGCCTGCTGGGCAAGGGCAACGTTTCTCAGCCGGATGCCCTGCGCGAGCAGGTGGCGGCGGGCGTCA
TTGGCCTGAAAATTCATGAGGACTGGGGCGCCACCCCGGCGGCGATCGACTGTGCGTTAACCGTCGCCGATGAAATGGAC
ATTCAGGTCGCCCTGCACAGCGACACCCTCAATGAGTCCGGTTTTGTGGAAGATACCCTCGCCGCCATCGGCGGGCGCAC
TATTCACACCTTCCATACCGAAGGGGCCGGCGGCGGCCATGCGCCGGACATCATCACCGCCTGCGCCCATCCGAACATTT
TGCCGTCGTCCACCAACCCAACGCTGCCCTACACCCTCAACACCATCGATGAACATCTCGATATGCTGATGGTCTGCCAC
CATCTGGACCCGGACATTGCTGAGGACGTGGCCTTTGCCGAATCGCGCATTCGCCGGGAAACCATCGCCGCGGAAGACGT
GCTGCACGACCTCGGCGCTTTCTCGCTCACCTCCTCCGATTCGCAGGCCATGGGTCGCGTCGGGGAAGTGGTTCTCCGCA
CCTGGCAGGTGGCGCATCGCATGAAGGTACAGCGCGGAGCGCTGACGGAGGAGACCGGGGATAACGACAACTTCCGCGTG
AAGCGCTACATCGCCAAATACACTATCAACCCGGCGCTGACCCACGGCATCGCGCACGAAGTCGGATCCATTGAGGTGGG
TAAGCTGGCGGACCTCGTGGTCTGGTCACCAGCCTTCTTTGGTGTGAAACCGGCCACCGTGATCAAAGGCGGCATGATCG
CCATCGCGCCGATGGGCGATATCAATGCCTCGATTCCGACCCCGCAGCCGGTGCACTACCGTCCGATGTTTGGCGCCCTG
GGCAGCGCCCGCCATCACTGCCGCCTCACCTTCCTGTCGCAGGCGGCGGCGGACAACGGCGTTGCCGAACGGCTGAACCT
GCGCAGCGCGATCGCCGTGGTAAAAGGCTGCCGTACGGTGCAGAAAGCCGACATGGTGCACAACAGCCTGCAGCCTAACA
TCACCGTCGACGCGCAGACTTATGAGGTGCGGGTGGATGGCGAACTCATCACCAGCGAGCCGGCAGACGTTCTGCCGATG
GCGCAACGATATTTTCTGTTTTAA

Protein sequence :
MSNISRQAYADMFGPTVGDKVRLADTELWIEVEDDLTTYGEEVKFGGGKVIRDGMGQGQMLAADCVDLVLTNALIVDHWG
IVKADIGVKDGRIFAIGKAGNPDIQPNVTIPIGAATEVIAAEGKIVTAGGIDTHIHWICPQQAEEALVSGVTTMVGGGTG
PAAGTHATTCTPGPWYISRMLQAADSLPVNIGLLGKGNVSQPDALREQVAAGVIGLKIHEDWGATPAAIDCALTVADEMD
IQVALHSDTLNESGFVEDTLAAIGGRTIHTFHTEGAGGGHAPDIITACAHPNILPSSTNPTLPYTLNTIDEHLDMLMVCH
HLDPDIAEDVAFAESRIRRETIAAEDVLHDLGAFSLTSSDSQAMGRVGEVVLRTWQVAHRMKVQRGALTEETGDNDNFRV
KRYIAKYTINPALTHGIAHEVGSIEVGKLADLVVWSPAFFGVKPATVIKGGMIAIAPMGDINASIPTPQPVHYRPMFGAL
GSARHHCRLTFLSQAAADNGVAERLNLRSAIAVVKGCRTVQKADMVHNSLQPNITVDAQTYEVRVDGELITSEPADVLPM
AQRYFLF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ureC NP_286680.1 urease subunit alpha Virulence TAI Protein 0.0 91
ureC NP_287088.1 urease subunit alpha Not tested TAI Protein 0.0 91
ureC YP_005684266.1 Urease alpha subunit Not tested PiCp 7 Protein 2e-166 64
ureC YP_003784325.1 urease subunit alpha Not tested PiCp 7 Protein 1e-166 64
ureC YP_005686358.1 Urease alpha subunit Not tested PiCp 7 Protein 1e-166 64
ureC YP_005682174.1 Urease alpha subunit Not tested PiCp 7 Protein 1e-166 64

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Kvar_0628 YP_003437570.1 urease subunit alpha VFG0270 Protein 5e-154 62