Gene Information

Name : Kvar_4985 (Kvar_4985)
Accession : YP_003441888.1
Strain : Klebsiella variicola At-22
Genome accession: NC_013850
Putative virulence/resistance : Unknown
Product : O-succinylhomoserine (thiol)-lyase
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0626
EC number : 2.5.1.48
Position : 5330445 - 5331605 bp
Length : 1161 bp
Strand : -
Note : KEGG: kpe:KPK_5446 cystathionine gamma-synthase; TIGRFAM: O-succinylhomoserine (thiol)-lyase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein

DNA sequence :
ATGACGCGTAAACAGGCCACCATCGCAGTGCGTAGCGGTTTAAATGACGACGAGCAGTACGGTTGCGTTGTCCCGCCGAT
CCACCTTTCCAGTACCTATAACTTTACCGGCTTTAATGAACCTCGCGCCCACGACTACTCCCGCCGCGGCAACCCGACGC
GTGATGTGGTGCAGCGCGCCTTAGCGGAGCTGGAAGGTGGCGCCGGCGCGGTGCTGACCAATACCGGTATGTCGGCGATC
CTGCTGGTGACGACGGTGTTCCTTAAGCCGGGCGATCTGCTGGTGGCGCCGCACGACTGCTACGGCGGCAGCTACCGTCT
GTTCGACAGCCTGGCGAAGCGCGGCTGTTATCGCGTCCAGTTCGTCGATCAAAATGATGAGCAGGCGCTGCGGGCGGCGT
TGGCGGAAAAACCGAAGCTGGTGCTGGTCGAAAGCCCAAGTAATCCATTGCTGCGGGTGGTGGATATTGCGAAAATCTGT
GGTCTGGCGCGTGAGGCAGGCGCGGTGAGCGTGGTGGACAACACCTTCCTGAGCCCGGCGCTGCAAAACCCGCTGGCGCT
GGGCGCCGATCTGGTGTTGCATTCCTGTACTAAATACCTGAATGGCCACTCCGATGTGGTTGCCGGGGTGGTGATTGCCA
ACGATCCGGCGACTGTCACCGAACTGGCATGGTGGGCGAATAATATTGGCGTCACCGGCGGCGCCTTCGACAGCTATTTG
TTGCTGCGCGGTCTGCGGACGCTGTCTCCGCGTATGGAAGTGGCGCAGCGTAATGCCCTGGCGATTGTTGAGTATCTGAA
AACCCAGCCGCTGGTGAAAAAGCTGTATCATCCGTCGCTGCCGGAAAACCAGGGGCATGAAATTGCGGCGCGTCAGCAAA
AAGGTTTTGGCGCAATGTTAAGCTTCGAGCTGGACGGTGACGAGCAGACGCTGCGCCGTTTCCTGAGCGGGCTGTCGCTG
TTTACACTGGCGGAATCGCTGGGGGGCGTTGAAAGCCTGATTTCCCATGCGGCAACGATGACGCATGCCGGCATGGCGCC
TGAAGCGCGTGCCGCCGCCGGAATTTCAGAAACGCTTCTGCGTATTTCAACCGGTATTGAAGATGGTGAAGATTTAATTG
CCGACCTGGAAAATGGCTTCCGGGCAGCAAACGAGGAATAA

Protein sequence :
MTRKQATIAVRSGLNDDEQYGCVVPPIHLSSTYNFTGFNEPRAHDYSRRGNPTRDVVQRALAELEGGAGAVLTNTGMSAI
LLVTTVFLKPGDLLVAPHDCYGGSYRLFDSLAKRGCYRVQFVDQNDEQALRAALAEKPKLVLVESPSNPLLRVVDIAKIC
GLAREAGAVSVVDNTFLSPALQNPLALGADLVLHSCTKYLNGHSDVVAGVVIANDPATVTELAWWANNIGVTGGAFDSYL
LLRGLRTLSPRMEVAQRNALAIVEYLKTQPLVKKLYHPSLPENQGHEIAARQQKGFGAMLSFELDGDEQTLRRFLSGLSL
FTLAESLGGVESLISHAATMTHAGMAPEARAAAGISETLLRISTGIEDGEDLIADLENGFRAANEE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAR0460 YP_039909.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 3e-58 42
SAS0418 YP_042545.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 1e-59 42