Gene Information

Name : Kvar_4536 (Kvar_4536)
Accession : YP_003441442.1
Strain : Klebsiella variicola At-22
Genome accession: NC_013850
Putative virulence/resistance : Virulence
Product : winged helix family two component transcriptional regulator
Function : -
COG functional category : T : Signal transduction mechanisms
COG ID : COG0745
EC number : -
Position : 4813359 - 4814042 bp
Length : 684 bp
Strand : -
Note : KEGG: kpe:KPK_4903 DNA-binding transcriptional activator CusR; TIGRFAM: heavy metal response regulator; PFAM: response regulator receiver; transcriptional regulator; SMART: response regulator receiver

DNA sequence : 
GTGAAGATTTTGATTGTCGAAGATGAGAAGAAAACCGGAGAGTACCTGACCAAAGGGCTCACCGAGGCCGGCTTCGTCGT
CGACCTGGCCGATAACGGCCTTAACGGCTATCACCTGGCAATGACCAGCGATTACGATCTGCTGATCCTCGACATCATGC
TGCCGGATGTGAACGGCTGGGATATCGTCCGCATGCTGCGGGCTGCCAATAAAGGGATGCCGATCCTGCTGCTCACCGCG
CTTGGCACTATCGAGCATCGGGTGAAGGGGCTGGAGCTGGGCGCCGACGACTATCTGGTGAAGCCATTTGCTTTTGCGGA
GCTGCTGGCGCGAGTGCGGACCCTGCTGCGCCGTGGAGCGGCGGTCATCGTCGAAAGCCAGTTTCAGGCGGGGGATCTCA
GCGTCGATTTGGTCAGCCGCAAGGTGACGCGCGGCGCGACGCGTATCACCCTGACCAGTAAGGAATTCACTCTGCTGGAG
TTCTTCCTGCGCCATCAGGGCGAGGTGCTGCCGCGTTCGCTGATTGCCTCGCAGGTCTGGGATATGAATTTCGACAGCGA
CACTAACGCCATTGACGTGGCGGTGAAGCGGCTGCGCGCCAAAATTGATAACGACTTCGAGCCGAAGCTAATCCAGACCG
TGCGCGGCGTCGGCTATATGCTTGAGGTGCCGGATGGCCGCTAA

Protein sequence : 
MKILIVEDEKKTGEYLTKGLTEAGFVVDLADNGLNGYHLAMTSDYDLLILDIMLPDVNGWDIVRMLRAANKGMPILLLTA
LGTIEHRVKGLELGADDYLVKPFAFAELLARVRTLLRRGAAVIVESQFQAGDLSVDLVSRKVTRGATRITLTSKEFTLLE
FFLRHQGEVLPRSLIASQVWDMNFDSDTNAIDVAVKRLRAKIDNDFEPKLIQTVRGVGYMLEVPDGR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
copR NP_460069.2 transcriptional regulatory protein YedW Not tested SPI-5 Protein 2e-55 52
copR AAC33719.1 regulatory protein CopR Not tested SPI-5 Protein 2e-55 52

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Kvar_4536 YP_003441442.1 winged helix family two component transcriptional regulator BAC0111 Protein 2e-100 95
Kvar_4536 YP_003441442.1 winged helix family two component transcriptional regulator BAC0347 Protein 4e-87 82
Kvar_4536 YP_003441442.1 winged helix family two component transcriptional regulator BAC0083 Protein 7e-71 63
Kvar_4536 YP_003441442.1 winged helix family two component transcriptional regulator BAC0638 Protein 4e-63 62
Kvar_4536 YP_003441442.1 winged helix family two component transcriptional regulator BAC0308 Protein 8e-63 58
Kvar_4536 YP_003441442.1 winged helix family two component transcriptional regulator BAC0197 Protein 5e-63 58
Kvar_4536 YP_003441442.1 winged helix family two component transcriptional regulator BAC0125 Protein 6e-65 56
Kvar_4536 YP_003441442.1 winged helix family two component transcriptional regulator AE000516.2.gene3505. Protein 6e-27 42

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Kvar_4536 YP_003441442.1 winged helix family two component transcriptional regulator VFG0596 Protein 9e-56 52
Kvar_4536 YP_003441442.1 winged helix family two component transcriptional regulator VFG1390 Protein 1e-44 45