Gene Information

Name : Kvar_4290 (Kvar_4290)
Accession : YP_003441199.1
Strain : Klebsiella variicola At-22
Genome accession: NC_013850
Putative virulence/resistance : Unknown
Product : UDP-N-acetylmuramoylalanine/D-glutamate ligase
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG0771
EC number : -
Position : 4531411 - 4532727 bp
Length : 1317 bp
Strand : -
Note : TIGRFAM: UDP-N-acetylmuramoylalanine/D-glutamate ligase; PFAM: Mur ligase middle domain protein; transmembrane protein 65; cytoplasmic peptidoglycan synthetase domain protein; KEGG: kpe:KPK_4649 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase

DNA sequence :
ATGGCAGATTATCAGGGTAAAAAAGTCGTCATTATTGGGCTGGGTATGACCGGCCTGTCATGCGTGGACTTTTTCATGGC
GCGCGGCGTGACGCCGCGTGTAATGGACACCCGCGTCGCGCCTCCGGGGCTGGATAAATTACCCGAATCGGTCGAATGCC
ATGTCGGCGGACTCAATGATACCTGGCTGCTGGCGGCGGATCTGATTGTCGCCAGTCCAGGCATCGCGCTGGCCCATCCT
TCACTGAGCGCGGCAGCCGATGCAGGCGTAGAGATCGTTGGTGATATCGAGCTGTTCTGCCGCGAGGCGCAGGCGCCGAT
TATCGCCATTACCGGCTCTAACGGCAAAAGCACTGTCACTACTCTGGTGGGCGAGATGGCGAAAGCGGCCGGGGTTAACG
TCGGCGTGGGCGGTAATATCGGCCTGCCGGCGCTGATGCTGCTGGACACCGATCGTGAGCTATATGTGCTGGAGCTCTCC
AGCTTCCAGCTGGAAACGACCTCCAGCCTGCAGGCGGTGGCGGCAACCATCCTCAACGTGACTGAGGACCATATGGACCG
CTACCCGCTGGGGCTGCAGCAGTATCGCGCGGCGAAGCTGCGGATTTACGAGAATGCAAAAACCTGCGTGGTGAACGCGG
ACGATGCGCTCACGATGCCGGTACGCGGGGCGGACGATCGCTGCATCAGCTTTGGTGTCGATGTCGGTGACTACCACCTT
AACCGTCAGCAGGGCGAAACCTGGCTGCGCGTTAAAGGTGAGAAAGTCCTCAATGTGAAAGAGATGCCTCTCACCGGTCA
GCATAACTACAGCAACGCCCTGGCGGCACTGGCGCTGGCCGATGCCGCGGGCCTGCCGCGGGCCAGTAGCCTCAAGGCAT
TAACCACCTTTACTGGCCTGGCCCATCGCTTTCAGCTGGTGCTGGATCACAACGGCGTACGCTGGATTAACGACTCGAAG
GCAACCAACGTCGGCAGCACCGAGGCGGCGCTGAACGGCCTGCAGCTCGACGGCACGCTGTATCTGCTGCTGGGCGGCGA
CGGCAAGTCCGCTGATTTTACCCCGCTGAAGCGCTACCTCGGCGGCGATCGTATTCGCTTGTACTGTTTTGGTCGCGATG
GCGCCGAGCTCGCTGAGCTGCGTCCTGACGTGGCGGTACAAACTGAAACCATGGAACAGGCGATGCGTCAGATAGCGCCC
CTGGTGAAAGCGGGCGACATGGTTCTCCTGTCGCCGGCGTGCGCCAGCCTGGATCAGTTTAAGAATTTTGAACAACGGGG
CGATATGTTTGCCCGTCTGGCGAAGGAGTTAGGTTGA

Protein sequence :
MADYQGKKVVIIGLGMTGLSCVDFFMARGVTPRVMDTRVAPPGLDKLPESVECHVGGLNDTWLLAADLIVASPGIALAHP
SLSAAADAGVEIVGDIELFCREAQAPIIAITGSNGKSTVTTLVGEMAKAAGVNVGVGGNIGLPALMLLDTDRELYVLELS
SFQLETTSSLQAVAATILNVTEDHMDRYPLGLQQYRAAKLRIYENAKTCVVNADDALTMPVRGADDRCISFGVDVGDYHL
NRQQGETWLRVKGEKVLNVKEMPLTGQHNYSNALAALALADAAGLPRASSLKALTTFTGLAHRFQLVLDHNGVRWINDSK
ATNVGSTEAALNGLQLDGTLYLLLGGDGKSADFTPLKRYLGGDRIRLYCFGRDGAELAELRPDVAVQTETMEQAMRQIAP
LVKAGDMVLLSPACASLDQFKNFEQRGDMFARLAKELG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00311 YP_008207776.1 UDP-N-acetylmuramoylalanine-D-glutamate ligase Not tested AbaR25 Protein 1e-51 43
BJAB0868_00315 YP_008211641.1 UDP-N-acetylmuramoylalanine-D-glutamate ligase Not tested AbaR26 Protein 1e-51 43