Gene Information

Name : Kvar_4222 (Kvar_4222)
Accession : YP_003441131.1
Strain : Klebsiella variicola At-22
Genome accession: NC_013850
Putative virulence/resistance : Virulence
Product : general secretion pathway protein D
Function : -
COG functional category : N : Cell motility
COG ID : COG1450
EC number : -
Position : 4456561 - 4458516 bp
Length : 1956 bp
Strand : +
Note : TIGRFAM: general secretion pathway protein D; PFAM: type II and III secretion system protein; NolW domain protein; KEGG: kpe:KPK_4576 pullulanase secretion envelope protein PulD

DNA sequence :
ATGCTGACTGTGCTGCTGATATTAACGCCGCTGCTATTTCGTCCGGCCATCGCAGAAGAATTTTCCGCCAGCTTTAAAGG
CACCGATATCCAGGAATTTATCAATACCGTCAGCAAAAACCTGAATAAAACGGTGATTATCGATCCCAGCGTGCGCGGCA
CCATTACCGTACGCAGTTACGATATGCTCAATGAAGAGCAATATTATCAATTCTTCCTTAGCGTGCTGGATGTGTATGGC
TTCGCCGTGATCAATATGAATAACGGCGTACTGAAGGTGGTGCGGGCTAAAGATGCGAAAACCTCGGCCGTCCCAGTCGC
CAGCGAGGCAGCACCGGGCGAAGGCGATGAAGTGGTCACCCGGGTGGTGCCCCTGACCAACGTCGCCGCCCGCGATCTCG
CCCCGCTGCTTCGCCAGCTGAACGATAACGCCGGCGCCGGCAGCGTGGTCCATTATGAGCCCTCCAACGTATTGCTGATG
ACCGGCCGCGCAGCGGTCATCAAACGCCTGCTGACCATTGTCGAGCGCGTCGACAACGCCGGGGATCGCAGCGTGGTGAC
CGTTCCCCTCTCCTGGGCCTCCGCCGCGGAGGTGGTCAAACTGGTTACCGAGCTCAATAAAGACAGCAGTAAGTCGGCGC
TGCCGGGCTCGATGGTGGCGAACGTGGTGGCCGATGAGCGCACCAACGCGGTACTGGTCAGCGGCGAGCCGAACTCGCGC
CAGCGCATTATCGCCATGATCAAACAGCTCGACCGCCAGCAGGCGGTGCAGGGCAACACCAAAGTGATCTACCTGAAGTA
CGCCAAAGCCGCCGATCTGGTGGAGGTCCTCACCGGGATCAGCAGCTCACTGCAGAACGATAAGCAAAGCGCCAAACCGG
TGGCCGCGATCGACAAAAATATCATTATCAAAGCCCACGGCCAGACCAACGCCCTGATCGTCACCGCGGCGCCGGACGTG
ATGAACGATCTTGAGCGAGTGATCGCCCAGCTCGATATCCGCCGCCCGCAGGTGCTGGTGGAGGCGATTATCGCCGAAGT
GCAGGATGCCGACGGCCTCAACCTCGGTATCCAGTGGGCCAATAAAAATGCCGGCATGACCCAGTTCACCAACAGCGGGC
TGCCGATCTCCACGGTTATCGCTGGCGCCAACCAATACAACAAAGACGGTACCGTCAGCAGCTCGCTGGCCAGCGCTCTG
GGCTCGTTTAACGGTATCGCCGCCGGCTTCTATCAGGGGAACTGGGCGATGCTGCTCACCGCTCTCTCCAGCAGTACCAA
GAACGATATTCTGGCCACTCCCAGCATCGTCACCCTCGACAACATGCAAGCCACCTTTAACGTCGGCCAGGAAGTTCCGG
TATTAACCGGCTCGCAAACCACCTCCGGCGACAACATCTTTAATACCGTCGAGCGCAAAACCGTCGGCATTAAGCTGAAG
GTGAAACCGCAGATTAACGAAGGCGATGCCGTGCTGCTGGAGATTGAGCAGGAGGTATCGAGCGTCGCCGACTCGGCCTC
CAGCACCAGTAGCGATCTCGGCGCGACCTTCAATACCCGGACGGTGAATAACGCCGTGCTGGTCGGCAGCGGTGAAACGG
TGGTGGTTGGCGGGCTGCTGGATAAAAGCGTCACCGATACCGCCGACAAAGTGCCGCTGCTCGGCGACATCCCGGTGATC
GGCGCCCTGTTCCGCTCCGAGAGCAAGAAAGTGTCGAAACGCAACCTGATGCTGTTTATCCGTCCGACCATCATTCGCGA
TCGTGATGAGTACCGTCAGGCCTCTTCCGGCCAGTACACCGCATTCGACAATGCGCAAACCAAACAGCGGGGCAAAGACA
GCAGCGAAGCGACACTCAGTAATGACCTGCTGCACATCTATCCAAAGCAGGAGACCCAGGCCTTCCGCCAGGTCAGCGCC
GCCATTGACGCCTTTAACCTCGGAGGCCGTCCATGA

Protein sequence :
MLTVLLILTPLLFRPAIAEEFSASFKGTDIQEFINTVSKNLNKTVIIDPSVRGTITVRSYDMLNEEQYYQFFLSVLDVYG
FAVINMNNGVLKVVRAKDAKTSAVPVASEAAPGEGDEVVTRVVPLTNVAARDLAPLLRQLNDNAGAGSVVHYEPSNVLLM
TGRAAVIKRLLTIVERVDNAGDRSVVTVPLSWASAAEVVKLVTELNKDSSKSALPGSMVANVVADERTNAVLVSGEPNSR
QRIIAMIKQLDRQQAVQGNTKVIYLKYAKAADLVEVLTGISSSLQNDKQSAKPVAAIDKNIIIKAHGQTNALIVTAAPDV
MNDLERVIAQLDIRRPQVLVEAIIAEVQDADGLNLGIQWANKNAGMTQFTNSGLPISTVIAGANQYNKDGTVSSSLASAL
GSFNGIAAGFYQGNWAMLLTALSSSTKNDILATPSIVTLDNMQATFNVGQEVPVLTGSQTTSGDNIFNTVERKTVGIKLK
VKPQINEGDAVLLEIEQEVSSVADSASSTSSDLGATFNTRTVNNAVLVGSGETVVVGGLLDKSVTDTADKVPLLGDIPVI
GALFRSESKKVSKRNLMLFIRPTIIRDRDEYRQASSGQYTAFDNAQTKQRGKDSSEATLSNDLLHIYPKQETQAFRQVSA
AIDAFNLGGRP

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
gspD CAE85234.1 GspD, hypothetical type II secretion protein Not tested PAI V 536 Protein 2e-126 47
gspD YP_854407.1 type II secretion protein GspD Not tested PAI I APEC-O1 Protein 5e-134 47

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Kvar_4222 YP_003441131.1 general secretion pathway protein D VFG2047 Protein 8e-124 46