Gene Information

Name : Kvar_4182 (Kvar_4182)
Accession : YP_003441091.1
Strain : Klebsiella variicola At-22
Genome accession: NC_013850
Putative virulence/resistance : Virulence
Product : lysine decarboxylase
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG1982
EC number : 4.1.1.18
Position : 4403923 - 4406076 bp
Length : 2154 bp
Strand : -
Note : PFAM: Orn/Lys/Arg decarboxylase major region; Orn/Lys/Arg decarboxylase domain protein; KEGG: kpe:KPK_4534 lysine decarboxylase, constitutive

DNA sequence :
GTGAATATCATCGCCATCATGGGGCCTCACGGCGTCTACCACAAAGACGAGCCGATCAAAGAACTGGAAGCGGCGCTGCA
GCGCCAGGGCTTCCAGACCATCTGGCCGCAAAACAGCGCCGACCTGCTGCAGTTTATTGAGCACAACCCGCGCATCTGCG
GGGTGATCTTCGACTGGGATGAATACAGCGTCGATCTGTGCAGCGATATCAATCAGCTCAATGAATATCTGCCCCTGTAC
GCCTTTATTAATGCCCACTCGACGATGGACGTCAGCAGTCAGGATCTGCGTATGACGCTGTGGTTCTTCGAATATGCGCT
GGGACTCTCCGAAGAGATCGCCACCCGCATTGGGCAGTATACCCGCGAGTACCTGGACAATATCACCCCGCCGTTTACCC
GCGCGCTGTTTAACTATGTGCAGGAGGGGAAGTATACCTTTTGTACACCGGGCCATATGGGCGGTAGCGCCTATCAGAAA
AGCCCGGTGGGCTGCCTGTTCTATGATTTCTTTGGCGGAAATACGCTGAAGGCGGATGTCTCGATTTCGGTCACCGAGCT
GGGCTCCCTGCTGGATCATACCGGCCCGCATCTGGAGGCGGAGGAGTATATTGCCCGCGCCTTTGGCGCTGAACAGAGCT
ACATGGTGACCAATGGCACCTCGACGTCCAACAAAATTGTCGGTATGTACTCGGCGCCCGCCGGCAGCACGCTGCTGATT
GACCGTAACTGTCACAAATCACTGGCCCACCTGCTGATGATGAGCGATGTGGTTCCCTTGTGGCTGAAGCCGACCCGCAA
CGCGTTGGGGATCCTCGGCGGTATCCCCCGGCGCGAATTTACCCGCGACAGCATTCAGCAGAAAGTGCGCGACACGGGCG
GGGCGCAGTGGCCCGTGCATGCGGTGATCACCAACTCCACCTACGATGGTCTGCTCTATAACACCACCTGGCTTAAGGAG
ACGCTCGACGTCCCGTCGATCCATTTCGATTCCGCCTGGGTGCCCTATACCCATTTCCATCCGATATATCAGGGGAAAAG
CGGCATGAGCGGTGAGCGGATCCCCGGAAAAGTCATCTTCGAGACGCAGTCCACGCATAAGATGCTGGCCGCGCTGTCGC
AGGCCTCGCTGATCCACATTAAGGGCAACTATGATGAAGAGACCTTTAATGAAGCCTTTATGATGCATACCTCGACGTCG
CCGAGCTATCCCATCGTCGCGTCGATTGAGACCGCGGCGGCGATGCTGCGCGGTAACTCCGGTAAGCGCCTGATCCAGCG
CTCCATTGAGCGGGCGCTGGATTTCCGCAAAGAGGTGCAGCGACTGCGCGAGGAGTCGGACGGCTGGTTCTTTGATATCT
GGCAGCCGGAAGCGGTGGATAAAGCCGAGTGCTGGCCGGTGGCGCCTGGCGAAGACTGGCACGGTTTCAAAGATGCCGAT
GCGGATCATATGTATCTCGATCCGGTGAAGGTCACCATTCTGACGCCGGGCATGGACGAGCAGGGGAATATGGCTGAAGA
GGGGATCCCGGCGGCGCTGGTGGCGAAGTTCCTCGACGAGCGGGGCGTGGTGGTGGAAAAAACGGGCCCCTATAACCTGC
TGTTCCTGTTCAGCATCGGTATTGATAAAACCCGGGCGATGGGGCTGCTGCGCGGCCTGACCGAGTTCAAACGCGCCTAC
GATCTCAATCTGCGGGTGAAAAATATGTTGCCGGATCTCTACGCGGAAGATCCCGACTTCTACCGCAACATGCGGATCCA
GGATCTGGCGCAGGGGATCCACCGCTTGATCCGTCAGCACCAGCTACCGCAGCTGATGCTCAGCGCCTTTGACGTCCTGC
CGGAAATGAAAATGACGCCGCATCACGCCTGGCAGCGCCAGATTAAGGGTGAGGTGGAAACCATTGAACTGGAGAACCTG
GTCGGCCGGATTTCGGCCAACATGATCCTCCCTTATCCACCGGGCGTACCGCTGCTGATGCCGGGAGAGATGATCACGGA
GGAGAGCCGGGCAGTGCTCGATTTCCTGCTGATGCTCTGCTCCATCGGCCGTCATTACCCGGGGTTTGAGACCGATATTC
ACGGGGCGAAGCGCGATGAGGACGGCGTGTATCGGGTACGAGTCTTAAAAAATGACGAAAGGCTTGCGCGTTAA

Protein sequence :
MNIIAIMGPHGVYHKDEPIKELEAALQRQGFQTIWPQNSADLLQFIEHNPRICGVIFDWDEYSVDLCSDINQLNEYLPLY
AFINAHSTMDVSSQDLRMTLWFFEYALGLSEEIATRIGQYTREYLDNITPPFTRALFNYVQEGKYTFCTPGHMGGSAYQK
SPVGCLFYDFFGGNTLKADVSISVTELGSLLDHTGPHLEAEEYIARAFGAEQSYMVTNGTSTSNKIVGMYSAPAGSTLLI
DRNCHKSLAHLLMMSDVVPLWLKPTRNALGILGGIPRREFTRDSIQQKVRDTGGAQWPVHAVITNSTYDGLLYNTTWLKE
TLDVPSIHFDSAWVPYTHFHPIYQGKSGMSGERIPGKVIFETQSTHKMLAALSQASLIHIKGNYDEETFNEAFMMHTSTS
PSYPIVASIETAAAMLRGNSGKRLIQRSIERALDFRKEVQRLREESDGWFFDIWQPEAVDKAECWPVAPGEDWHGFKDAD
ADHMYLDPVKVTILTPGMDEQGNMAEEGIPAALVAKFLDERGVVVEKTGPYNLLFLFSIGIDKTRAMGLLRGLTEFKRAY
DLNLRVKNMLPDLYAEDPDFYRNMRIQDLAQGIHRLIRQHQLPQLMLSAFDVLPEMKMTPHHAWQRQIKGEVETIELENL
VGRISANMILPYPPGVPLLMPGEMITEESRAVLDFLLMLCSIGRHYPGFETDIHGAKRDEDGVYRVRVLKNDERLAR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
cadA NP_756988.1 lysine decarboxylase, inducible Not tested PAI II CFT073 Protein 0.0 70
unnamed CAD66195.1 putative cadaverin decarboxylase Virulence PAI III 536 Protein 0.0 63

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Kvar_4182 YP_003441091.1 lysine decarboxylase VFG1670 Protein 0.0 63