Gene Information

Name : Kvar_3879 (Kvar_3879)
Accession : YP_003440791.1
Strain : Klebsiella variicola At-22
Genome accession: NC_013850
Putative virulence/resistance : Virulence
Product : lysine decarboxylase
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG1982
EC number : 4.1.1.18
Position : 4085172 - 4087319 bp
Length : 2148 bp
Strand : -
Note : PFAM: Orn/Lys/Arg decarboxylase major region; Orn/Lys/Arg decarboxylase domain protein; KEGG: kpu:KP1_1410 lysine decarboxylase 1

DNA sequence :
ATGAACGTTATTGCAATCATGAATCACATGGGTGTTTACTTCAAAGAAGAACCCATCCGTGAACTGCATCGTGCTCTCGA
ACGCCTGGACTTCCGTATTGTCTACCCGAACGACCGTGACGACTTATTAAAACTTATCGAAAACAACTCTCGTCTGTGCG
GCGTGATCTTCGACTGGGATAAATACAATCTCGAACTGTGCGAAGAAATCAGCAAAATGAACGAGTACATGCCGCTGTAC
GCGTTCGCTAACACCTACTCGACTCTGGACGTTAGCCTGAACGATCTGCGCATGCAGGTTCGCTTCTTCGAATATGCGCT
GGGCGCTGCGGAAGATATCGCGAACAAAATCAAACAGAACACTGACGAATACATCGACACCATTCTGCCGCCGCTGACCA
AAGCGCTGTTCAAATATGTACGTGAAGGCAAATACACCTTCTGTACCCCTGGCCACATGGGCGGTACCGCGTTCCAGAAA
AGCCCGGTAGGCAGCATCTTCTATGATTTCTTTGGCCCGAATACCATGAAATCCGATATCTCCATTTCGGTTTCTGAACT
GGGTTCCCTGCTGGACCACAGCGGCCCGCACAAAGAAGCGGAAGAGTATATCGCTCGCGTCTTTAACGCAGAACGCAGCT
ACATGGTGACCAACGGTACCTCTACTGCTAACAAAATCGTCGGCATGTACTCCGCGCCGGCCGGCAGCACCGTGCTGATT
GACCGTAACTGCCACAAATCGCTGACTCACCTGATGATGATGAGCGACATTACGCCGATCTACTTCCGTCCGACCCGTAA
CGCCTACGGTATCCTCGGCGGTATTCCGCAGAGCGAATTTCAGCACGCGACTATCGCCAAGCGTGTGAAAGAGACGCCGA
ATGCGACCTGGCCGGTACACGCGGTGATCACCAACTCAACCTATGATGGTCTGCTGTATAACACCGACTTCATCAAGAAA
ACCCTGGATGTGAAATCCATCCACTTTGACTCCGCATGGGTCCCTTACACCAACTTCTCGCCGATCTATGAAGGCAAATG
CGGGATGAGCGGCGGCCGCGTCGAAGGGAAAGTGATCTACGAAACCCAGTCCACGCACAAACTGCTGGCGGCATTCTCCC
AGGCGTCGATGATCCACGTGAAAGGCGACGTAAACGAAGAGACCTTCAACGAAGCCTACATGATGCACACCACCACTTCC
CCGCACTACGGGATCGTGGCGTCCACCGAAACCGCGGCGGCGATGATGAAGGGTAACGCCGGTAAGCGTCTGATCGACGG
CTCTATTGAACGTTCCATCAAGTTCCGTAAAGAGATCAAACGTCTGAAAGGCGAGTCTGACGGCTGGTTCTTCGACGTCT
GGCAGCCGGAGCATATCGATGGTCCTGAATGCTGGCCGCTGCGTTCCGACAGCGCATGGCACGGTTTCAAAAACATCGAT
AACGAGCACATGTACCTCGACCCGATCAAAGTCACGCTGCTGACGCCGGGGATGAAGAAAGACGGCACCATGGATGACTT
CGGTATTCCGGCGAGCATCGTGGCGAAATATCTCGACGAACACGGCATCGTGGTTGAGAAAACCGGTCCGTACAACCTGC
TGTTCCTGTTCAGCATCGGTATCGACAAAACCAAAGCGCTGAGCCTGCTGCGTGCGCTGACCGACTTCAAACGCGCGTTC
GACCTGAACCTGCGGGTGAAAAACATGCTGCCGTCGCTGTACCGTGAAGATCCTGAATTCTATGAAAACATGCGTATTCA
GGACCTGGCGCAGAACATTCACAAACTGATTGAGCATCACAACCTGCCGGACCTGATGTTCCGCGCGTTTGAAGTGCTGC
CATCGATGGTGATGACCCCGTATGCCGCGTTCCAGAAAGAGCTGCACGGTCAGACTGAAGAGGTTTATCTCGAAGAGATG
GTCGGCCGCGTCAACGCCAACATGATCCTGCCGTATCCTCCGGGAGTACCGCTGGTGATGCCGGGTGAAATGATCACCGA
AGAAAGCCGCCCGGTGCTGGAGTTCCTGCAGATGCTGTGCGAAATCGGCGCCCACTACCCGGGCTTCGAAACCGATATCC
ACGGCGCCTATCGTCAGGCGGATGGTCGTTACACCGTTAAAGTGCTGAAAGAAGAAAACAACAAGTAA

Protein sequence :
MNVIAIMNHMGVYFKEEPIRELHRALERLDFRIVYPNDRDDLLKLIENNSRLCGVIFDWDKYNLELCEEISKMNEYMPLY
AFANTYSTLDVSLNDLRMQVRFFEYALGAAEDIANKIKQNTDEYIDTILPPLTKALFKYVREGKYTFCTPGHMGGTAFQK
SPVGSIFYDFFGPNTMKSDISISVSELGSLLDHSGPHKEAEEYIARVFNAERSYMVTNGTSTANKIVGMYSAPAGSTVLI
DRNCHKSLTHLMMMSDITPIYFRPTRNAYGILGGIPQSEFQHATIAKRVKETPNATWPVHAVITNSTYDGLLYNTDFIKK
TLDVKSIHFDSAWVPYTNFSPIYEGKCGMSGGRVEGKVIYETQSTHKLLAAFSQASMIHVKGDVNEETFNEAYMMHTTTS
PHYGIVASTETAAAMMKGNAGKRLIDGSIERSIKFRKEIKRLKGESDGWFFDVWQPEHIDGPECWPLRSDSAWHGFKNID
NEHMYLDPIKVTLLTPGMKKDGTMDDFGIPASIVAKYLDEHGIVVEKTGPYNLLFLFSIGIDKTKALSLLRALTDFKRAF
DLNLRVKNMLPSLYREDPEFYENMRIQDLAQNIHKLIEHHNLPDLMFRAFEVLPSMVMTPYAAFQKELHGQTEEVYLEEM
VGRVNANMILPYPPGVPLVMPGEMITEESRPVLEFLQMLCEIGAHYPGFETDIHGAYRQADGRYTVKVLKEENNK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
cadA NP_756988.1 lysine decarboxylase, inducible Not tested PAI II CFT073 Protein 0.0 95
unnamed CAD66195.1 putative cadaverin decarboxylase Virulence PAI III 536 Protein 0.0 67

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Kvar_3879 YP_003440791.1 lysine decarboxylase VFG1670 Protein 0.0 67