Gene Information

Name : Kvar_3431 (Kvar_3431)
Accession : YP_003440343.1
Strain : Klebsiella variicola At-22
Genome accession: NC_013850
Putative virulence/resistance : Virulence
Product : 3-deoxy-D-manno-octulosonate cytidylyltransferase
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG1212
EC number : 2.7.7.38
Position : 3580919 - 3581665 bp
Length : 747 bp
Strand : -
Note : KEGG: kpe:KPK_3614 3-deoxy-manno-octulosonate cytidylyltransferase; TIGRFAM: 3-deoxy-D-manno-octulosonate cytidylyltransferase; PFAM: acylneuraminate cytidylyltransferase

DNA sequence :
ATGAGTTTCGTGGTTATTATTCCTGCGCGTTTCGCCTCTACGCGCCTGCCGGGAAAACCACTGCAGGACATTAACGGCAA
ACCGATGATTGTCCATGTGCTGGAGCGCGCGCGCGAATCCGGCGCGGATCGCATTATTGTCGCCACCGATCATCCGGACG
TGGCCAGCGCCGTTGAAGCGGCGGGTGGTGAAGTGTGCATGACCCGCGCCGATCATCAGTCCGGCACTGAACGGCTGGCG
GAAGTGGTGGAGAAGTGCGCATTCAGCGATGACACTATCATCGTTAATATTCAGGGCGATGAGCCGATGATCCCCCCGGC
AATCGTCCGCCAGGTGGCGGAGAATCTGGCGTCCAGCAGCAGTGGAATGGCGACGCTGGCGGTACCGATCCACGATGCGG
AAGAGGCGTTTAATCCAAATGCGGTGAAAGTGGTGATGGATGCCCAGGGCTATGCGCTCTATTTTTCACGCGCCACCATT
CCGTGGGATCGCGATCGCTTTGCCCACTCCCGCGAGACCATCGGTGATTCCCTGCTGCGTCACATCGGCATTTATGGCTA
CCGCGCTGGCTTTATTCGCCGCTATGTCAGCTGGGCGCCGAGCCCGCTGGAGCAGATTGAAATGCTCGAGCAGCTGCGGG
TGCTGTGGTATGGCGAGAAAATCCATGTTGCCGTGGCGGCAGAAGTGCCCGGCACCGGTGTGGATACCCCGGAAGATCTG
GAGCGCGTCCGCGCTGAACTGCGTTAA

Protein sequence :
MSFVVIIPARFASTRLPGKPLQDINGKPMIVHVLERARESGADRIIVATDHPDVASAVEAAGGEVCMTRADHQSGTERLA
EVVEKCAFSDDTIIVNIQGDEPMIPPAIVRQVAENLASSSSGMATLAVPIHDAEEAFNPNAVKVVMDAQGYALYFSRATI
PWDRDRFAHSRETIGDSLLRHIGIYGYRAGFIRRYVSWAPSPLEQIEMLEQLRVLWYGEKIHVAVAAEVPGTGVDTPEDL
ERVRAELR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
kpsU YP_854332.1 3-deoxy-manno-octulosonate cytidylyltransferase Not tested PAI I APEC-O1 Protein 3e-34 46
kpsU AAZ04469.1 CMP-KDO synthetase Virulence PAI I APEC-O1 Protein 2e-34 46
kpsU CAE85213.1 KpsU protein Virulence PAI V 536 Protein 6e-35 46