Gene Information

Name : Kvar_2589 (Kvar_2589)
Accession : YP_003439511.1
Strain : Klebsiella variicola At-22
Genome accession: NC_013850
Putative virulence/resistance : Virulence
Product : fimbrial biogenesis outer membrane usher protein
Function : -
COG functional category : N : Cell motility
COG ID : COG3188
EC number : -
Position : 2699424 - 2701958 bp
Length : 2535 bp
Strand : -
Note : PFAM: fimbrial biogenesis outer membrane usher protein; KEGG: kpe:KPK_2634 outer membrane usher protein LpfC

DNA sequence :
ATGATGATGGCAATGGATTATATAAAAGTACGATCTCCACGGTTGGCATTGTTGATAACCATCGCGCTCTTCGGTAATAC
ACAAAATAGCTATAGTCGCGATTTTTTTAACCCAGAGCTGGTTGAACTGGATAATCCAGGGACAGAAAGAGTCGATCTTT
CAGGTTTTGAATCTGGTGCGCAAGCCCCCGGGAATTATCATGTTGATGTCGTCCTGGACGATCAGTTAGTCGATACTCGC
GATATCATGTTTGTTTTGCTGAAAGAACCTGGCGGTGATGAAAAATTAGTCCCCTGTTTATCCATTGAGCAATTAGCAAG
CTGGGGAGTCAAGACTGGACTTTTTCCTGCGTTAAAGGGAGAAACCTCCTGTGCGAACCTGTCCGCCATTCCTCAGGCCA
GTACAGATTTCCAGTTTGCCATGCAGCGTCTGGTATTGAGCATTCCGCAAGCGGCAATCTCAGCGCAAGCTCGTGGATCG
GTGCCACCGGATCGCTGGGATGAAGGGATTAACGCCGCCCTGCTTAACTACAGTCTGAGTGGGGCGAATAACTGGGCCAA
AAATAACAACAGCAGCAACAGTGATAGCCAGTATGCCAACCTGCGTCCGGGAGTAAACATCGGCCCCTGGAGGTTAAGAA
ATTACACCACCTGGTCGCGAGATTCACAGGGCCACGATGCCTGGGACACGGTTTATACCTATGCACAACGTACGATAATC
CCGTTAAAGTCGCAGCTCACACTGGGTGACAGTTCTGCCCCGGCAGATGTTTTCGACAGTATGCCTTTCCGGGGAGGACA
ACTTGCTTCCGATGATGACATGCTGCCCGACTCCCTTAAGGGCTATGCCCCTGTGGTGCGTGGTATCGCCCGGACCAATG
CCCAGGTGATCATCCGCCAGAATGGCTATCAGATTTACCAGAGCTTTGTGGCGCCGGGCGCGTTTGAAATTACGGACATG
TATCCTACCGGCGGCGCCGGCGATCTTGATGTCACGATTAAAGAGGCTGATGGTAGTGAGCAGCACTTTAGCGTGCCATT
TGCCTCACTTCCCGTATTACAGCGTGAAGGCCGAATAAAATATGCGTTAACGGGCGGCCAATATCGTTCGTACAACGGCA
GCGTGGATAAGACACCCTTTGGCCAGATGAGCGTTATTCTCGGCTTGCCCTACGGGTTCACGTTTTACGGTGGATTGCAG
GAGTCGAGTAAATATCAGTCGCTTGCCGCGGGCGTGGGTAAAAACATGGGTGACTTTGGCGCTATCTCCAGCGACATCAC
CCAGGGCTGGTCCACGCCGTACAATATGCCGAAATCCAACGGTCAATCCTGGCGGGCTCGATACAGTAAAAACTTTGCTT
CAACAGGCACTAACTTTGCGATTGCCGGCTACCGCTATTCGACCAGCGGCTACTATGGCATGCAGGAGGTCCTTGATTCT
TATGGTGACAGTAATGCGCTCCAGGATAGACGCCGAAACCGTGCGGAGCTGACGTTGAGCCAGGGGTTGGGAGATAATCT
GGGATCGTTGATGCTGAACGCCTCGCATGAAGATTACTGGAATTCAGGTAAGGCGATGGAATCCTGGAGCGTTGGGTATA
ACAACTACTGGCACAGTATCAGTTACGGTCTGACATGGACCCTGAGCAGGAATGGTAGTACGGGATCGTACAGCGCTCAC
CAGAGCGACGGTAAAAACCAGATGCTGGCGCTAAATATCAGCATCCCGCTGGAAAAACTCTTGCCGCAGACATGGGCAAA
CTATGGCATGAATGCCAGCAAGCATAACGGTACGACACACAGTGTTGGGTTGAATGGCGTTGCGATGCCGAATAATGCGC
TTAACTGGAATATTCAACAGGGTTACGGCACTCACGACGTGGCCTATACCGGCAATATGAATGGTGATTATCGAGGCACC
TATGGCGAACTGACGGCCGGGTACAGCTATGACAAAAATACCGACCGTCTGAATTATGGGATTCAGGGAGGCGTGGTTGC
GCATGCCAATGGCGTGACGTTCTCTCAGCCACTGGGTGAAACCAACGTGCTGATTGCTGCCCCCGGGGCTGCCGGTGTAG
GAATCCAGAATATGACCGGCGCGACAACCGATTATCGCGGATACACGCTTGCCTCTAACTTAATGCCTTATCGCAAAAAT
GATGTGTCATTAATCACTGAAACATTGCCGGCTAACGTTGAGTTAGAACAAACGGTCAAAACCGTGGTCCCGACGCGTGG
CGCGATTGTCAGGGCGAACTATCTGGCAAGCGTAGGCGTTCGCATGTTGATGAGCTTGACCCAGCAAAACGGCCAGTCGG
TTCCGTTTGGTGCAATTGCCAGCATTGAAGGCGCAGAACACAGCAGCTTTATCGTTGGCGAAAGCGGTCAGGTGTATTTG
ACGGGCCTGGCTCCCCAGGTCAACCTGACCGTGAAATGGGGAAATCAATCCGCAAACACCTGCAGGGTGCATTACTCGAT
TAATATGGCGAAGCTGAATAACGATGTGATTATCGATAATGCTGCTTGCCGTTAA

Protein sequence :
MMMAMDYIKVRSPRLALLITIALFGNTQNSYSRDFFNPELVELDNPGTERVDLSGFESGAQAPGNYHVDVVLDDQLVDTR
DIMFVLLKEPGGDEKLVPCLSIEQLASWGVKTGLFPALKGETSCANLSAIPQASTDFQFAMQRLVLSIPQAAISAQARGS
VPPDRWDEGINAALLNYSLSGANNWAKNNNSSNSDSQYANLRPGVNIGPWRLRNYTTWSRDSQGHDAWDTVYTYAQRTII
PLKSQLTLGDSSAPADVFDSMPFRGGQLASDDDMLPDSLKGYAPVVRGIARTNAQVIIRQNGYQIYQSFVAPGAFEITDM
YPTGGAGDLDVTIKEADGSEQHFSVPFASLPVLQREGRIKYALTGGQYRSYNGSVDKTPFGQMSVILGLPYGFTFYGGLQ
ESSKYQSLAAGVGKNMGDFGAISSDITQGWSTPYNMPKSNGQSWRARYSKNFASTGTNFAIAGYRYSTSGYYGMQEVLDS
YGDSNALQDRRRNRAELTLSQGLGDNLGSLMLNASHEDYWNSGKAMESWSVGYNNYWHSISYGLTWTLSRNGSTGSYSAH
QSDGKNQMLALNISIPLEKLLPQTWANYGMNASKHNGTTHSVGLNGVAMPNNALNWNIQQGYGTHDVAYTGNMNGDYRGT
YGELTAGYSYDKNTDRLNYGIQGGVVAHANGVTFSQPLGETNVLIAAPGAAGVGIQNMTGATTDYRGYTLASNLMPYRKN
DVSLITETLPANVELEQTVKTVVPTRGAIVRANYLASVGVRMLMSLTQQNGQSVPFGAIASIEGAEHSSFIVGESGQVYL
TGLAPQVNLTVKWGNQSANTCRVHYSINMAKLNNDVIIDNAACR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
fim2D AFH78429.1 putative fimbrial usher protein Virulence KpGI-5 Protein 3e-137 42
lpfC NP_839216.1 long polar fimbriae Not tested SHI-2 Protein 4e-136 41
lpfC NP_709462.1 long polar fimbriae Not tested SHI-2 Protein 4e-136 41
lpfC YP_006098365.1 fimbrial outer membrane usher protein Not tested Tn2411 Protein 3e-139 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Kvar_2589 YP_003439511.1 fimbrial biogenesis outer membrane usher protein VFG0454 Protein 2e-160 45
Kvar_2589 YP_003439511.1 fimbrial biogenesis outer membrane usher protein VFG0876 Protein 5e-142 41
Kvar_2589 YP_003439511.1 fimbrial biogenesis outer membrane usher protein VFG0446 Protein 6e-140 41