Gene Information

Name : Kvar_1222 (Kvar_1222)
Accession : YP_003438162.1
Strain : Klebsiella variicola At-22
Genome accession: NC_013850
Putative virulence/resistance : Unknown
Product : GMP synthase, small subunit
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : -
Position : 1289348 - 1290925 bp
Length : 1578 bp
Strand : +
Note : TIGRFAM: GMP synthase, small subunit; GMP synthase, large subunit; PFAM: GMP synthase domain protein; tRNA methyl transferase-like; glutamine amidotransferase class-I; KEGG: kpe:KPK_1284 GMP synthase

DNA sequence :
ATGACGGAAAACATTCATAAACATCGCATTCTCATTCTCGACTTCGGCTCTCAGTATACTCAGCTGGTGGCGCGTCGCGT
GCGTGAGCTGGGCGTCTACTGTGAGCTGTGGGCGTGGGATGTCACAGAAGCACAGATCCGCGAATTCAATCCAAGCGGCA
TCATTCTTTCCGGCGGCCCGGAAAGTACTACCGAAGAGAACAGCCCGCGCGCGCCGCAGTATGTGTTTGAAGCCGGCGTG
CCGGTATTTGGCGTCTGCTACGGCATGCAGACCATGGCGATGCAACTGGGCGGCCATGTGGAAGGTTCTAACGAGCGTGA
GTTTGGCTACGCGCAGGTTGAAGTGGTTAACGACAGCGCGCTGGTGCGCGGTATCGAAGACTCCCTGACCGCAGACGGTA
AACCGCTGCTGGACGTGTGGATGAGCCACGGCGACAAGGTCACCGCCATCCCGTCTGACTTCGTCACCGTCGCCAGCACC
GACAACTGCCCGTTCGCCATTATGGCCAACGAAGAAAAACGCTTCTACGGCGTGCAGTTCCACCCGGAAGTGACCCACAC
CCGTCAGGGGATGCGTATGCTGGAGCGCTTCGTGCGCGACATCTGCCAGTGCGAAGCCCTGTGGACCCCGGCGAAAATCA
TCGACGACGCCGTCGAGCGTATCCGCCAGCAGGTTGGCGATGACAAAGTGATCCTTGGCCTCTCCGGCGGCGTGGACTCC
TCCGTGACCGCGATGTTGCTGCACCGCGCCATCGGCAAAAACCTGACCTGCGTATTCGTGGATAACGGCCTCCTGCGTCT
GAATGAAGCGCAGCAGGTGATGGACATGTTTGGCGACCACTTTGGCCTGAACATTGTTCACGTCGAAGGCGAGCAGCGCT
TCCTCGACGCGCTGAAAGGCGAGAACGATCCGGAAGCGAAACGTAAAATCATCGGCCGCGTCTTCGTGGAAGTGTTCGAC
GAAGAAGCGCTGAAGCTGGACGACGTCAAATGGCTGGCGCAGGGCACCATCTACCCTGACGTTATCGAATCTGCCGCTTC
CGCTACCGGTAAAGCACACGTCATTAAATCTCACCACAATGTGGGCGGCCTGCCGAAAGAGATGAAGATGGGGCTGGTTG
AGCCGCTGCGTGAGCTGTTCAAAGACGAAGTGCGTAAGATCGGTCTGGAACTGGGCCTGCCGTACGATATGCTCTACCGT
CACCCGTTCCCGGGCCCGGGCCTCGGCGTGCGCGTGCTGGGCGAAGTGAAGAAAGAGTACTGCGACCTGCTGCGTCGTGC
GGACGCTATCTTCATCGAAGAGCTGCACAAAGCTGACCTGTACAACAAAGTGAGCCAGGCGTTTACCGTGTTCCTGCCGG
TTCGTTCCGTCGGCGTAATGGGCGATGGCCGTAAATACGACTGGGTCGTTTCCCTGCGTGCGGTGGAAACCATCGACTTT
ATGACCGCGCACTGGGCGCACCTGCCGTATGATTTCCTCGGCCGCGTCTCTAACCGCATTATCAATGAAGTGAACGGTAT
CTCCCGCGTGGTGTATGACATCAGCGGTAAGCCGCCAGCAACGATTGAGTGGGAATGA

Protein sequence :
MTENIHKHRILILDFGSQYTQLVARRVRELGVYCELWAWDVTEAQIREFNPSGIILSGGPESTTEENSPRAPQYVFEAGV
PVFGVCYGMQTMAMQLGGHVEGSNEREFGYAQVEVVNDSALVRGIEDSLTADGKPLLDVWMSHGDKVTAIPSDFVTVAST
DNCPFAIMANEEKRFYGVQFHPEVTHTRQGMRMLERFVRDICQCEALWTPAKIIDDAVERIRQQVGDDKVILGLSGGVDS
SVTAMLLHRAIGKNLTCVFVDNGLLRLNEAQQVMDMFGDHFGLNIVHVEGEQRFLDALKGENDPEAKRKIIGRVFVEVFD
EEALKLDDVKWLAQGTIYPDVIESAASATGKAHVIKSHHNVGGLPKEMKMGLVEPLRELFKDEVRKIGLELGLPYDMLYR
HPFPGPGLGVRVLGEVKKEYCDLLRRADAIFIEELHKADLYNKVSQAFTVFLPVRSVGVMGDGRKYDWVVSLRAVETIDF
MTAHWAHLPYDFLGRVSNRIINEVNGISRVVYDISGKPPATIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 6e-128 51
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 3e-128 51
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 3e-128 51
guaA NP_938969.1 GMP synthase Not tested Not named Protein 2e-111 47