Gene Information

Name : Kvar_1079 (Kvar_1079)
Accession : YP_003438019.1
Strain : Klebsiella variicola At-22
Genome accession: NC_013850
Putative virulence/resistance : Virulence
Product : aldehyde dehydrogenase (NAD(+))
Function : -
COG functional category : C : Energy production and conversion
COG ID : COG1012
EC number : 1.2.1.3
Position : 1127615 - 1129135 bp
Length : 1521 bp
Strand : +
Note : PFAM: aldehyde dehydrogenase; KEGG: kpe:KPK_1140 aldehyde dehydrogenase

DNA sequence :
ATGCGTTATGCACATCCTGGCCAGCCCGGCGCCCTGGTTTCATTTAAATCCGCTTACGGCAACTTCATTGACGGTAAATT
TGTCGAGCCGCTGAGCGGTGAATTCTTTATGAATACCTCCCCGGTCGACGGCAGCAACATTGCGCAGTTTCCCCGCTCGG
ACGCCAAAGACATTGAGTTCGCCCTCGATGCCGCTCACCGTGCGGCGCCGGCGTGGGGTAAAACGTCAGTGCAGCAGCGC
TCCAGGCTGCTGCTACAGGTCGCCGATCGTATTGAACAGCACCTGGAGTATCTGGCCGTCGCGGAGAGCTGGGACAACGG
GAAACCGATCCGCGAAACCCTGAATGCCGACCTGCCGCTGGCGGTGGACCATTTCCGCTACTTCGCCGGCTGCCTGCGCG
CCCAGGAGGGAAGCACCGCCGAGATTGACGAAACGACGGTGGCCTATCATTTCCATGAACCGCTGGGGGTGGTCGGGCAG
ATTATCCCGTGGAACTTTCCGCTGCTGATGGCCGCGTGGAAGCTGGCCCCGGCCCTGGCGGCGGGTAACTGCGTGGTGCT
CAAGCCGGCTGAACAGACGCCGCTGAGCATTACCCTGCTGCTGGAGCTGATCGGCGATCTGTTCCCGGCCGGGGTGCTTA
ACGTGGTACAGGGATTCGGCAAAGAGGCAGGCGAGGCGCTGGCCACCAGCAAGCGTATCGCCAAGCTGGCGTTCACTGGC
TCCACGCCGGTCGGGCGGCATATTCTCGCCTGCGCGGCGGAAAATATTATCCCCTGCACTGTCGAGCTGGGGGGCAAATC
GCCCAACATCTACTTCGCCGACGTAATGGAGGGAGAAGAGGAGTTTATTGAGAAGGCGGTGGAGGGACTGGTGCTTGGCT
TCTTCAACCAGGGGGAGGTATGTACCTGCCCGTCGCGGGCGCTGATCCATGAATCCATCTATGAGCCCTTTATGGCGCGG
GTCATGGAGAAGGTGGCGCAGATCCGCCGTGGTGACCCGTTAGATACCGACACCATGATCGGCGCGCAGGCTTCCCGCCA
GCAGTTCGATAAGATCCTCTCCTACATTCAGATTGCGCGGGAAGAGGGCGGGCAAATTCTGACCGGCGGCGAGCGGGCGG
CTATCGCGCCGGCGCTGGATAACGGTTTTTATATTCAGCCCACGCTGATTAAAGGCCGCAACGATATGCGCAGCTTCCAG
GAGGAGATCTTTGGGCCCGTGATCGGGGTGACCACCTTTAAGGACGAAGCGGAAGCGCTGACCATCGCCAATGAGACCCA
GTTTGGCCTTGGCGCCGGGGTCTGGACGCGGGATACCAACCTCGCCTATCGCATGGGCCGCGGGATTAAAGCCGGCCGCG
TATGGACCAACTGCTATCATGTCTACCCGGCGCATGCGGCGTTCGGTGGCTATAAACAGTCCGGCGTCGGCCGGGAAACG
CACAAGATGGCGCTGGATGCCTATCAGCAAACCAAAAATCTGCTGGTGAGCTACGGCACCGCGCCGCTGGGCCTGTTCTA
A

Protein sequence :
MRYAHPGQPGALVSFKSAYGNFIDGKFVEPLSGEFFMNTSPVDGSNIAQFPRSDAKDIEFALDAAHRAAPAWGKTSVQQR
SRLLLQVADRIEQHLEYLAVAESWDNGKPIRETLNADLPLAVDHFRYFAGCLRAQEGSTAEIDETTVAYHFHEPLGVVGQ
IIPWNFPLLMAAWKLAPALAAGNCVVLKPAEQTPLSITLLLELIGDLFPAGVLNVVQGFGKEAGEALATSKRIAKLAFTG
STPVGRHILACAAENIIPCTVELGGKSPNIYFADVMEGEEEFIEKAVEGLVLGFFNQGEVCTCPSRALIHESIYEPFMAR
VMEKVAQIRRGDPLDTDTMIGAQASRQQFDKILSYIQIAREEGGQILTGGERAAIAPALDNGFYIQPTLIKGRNDMRSFQ
EEIFGPVIGVTTFKDEAEALTIANETQFGLGAGVWTRDTNLAYRMGRGIKAGRVWTNCYHVYPAHAAFGGYKQSGVGRET
HKMALDAYQQTKNLLVSYGTAPLGLF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
VC0819 NP_230467.2 aldehyde dehydrogenase Not tested VPI-1 Protein 1e-154 66
aldA AAC12273.1 aldehyde dehydrogenase Virulence VPI Protein 1e-160 64
aldA AAK20747.1 aldehyde dehydrogenase Virulence VPI Protein 1e-160 64
aldA AAK20776.1 aldehyde dehydrogenase Virulence VPI Protein 1e-160 64
aldA-1 YP_001216300.1 aldehyde dehydrogenase Not tested VPI-1 Protein 7e-160 64
ORF SG19 AAN62241.1 putative aldehyde dehydrogenase Not tested PAGI-3(SG) Protein 2e-57 42

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Kvar_1079 YP_003438019.1 aldehyde dehydrogenase (NAD(+)) VFG0082 Protein 5e-155 66