Gene Information

Name : HTH_1295 (HTH_1295)
Accession : YP_003432949.1
Strain : Hydrogenobacter thermophilus TK-6
Genome accession: NC_013799
Putative virulence/resistance : Virulence
Product : UDP-glucose/GDP-mannose dehydrogenase
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG0677
EC number : -
Position : 1180670 - 1181983 bp
Length : 1314 bp
Strand : -
Note : -

DNA sequence :
GTGATTGACTTTAAAAGTCTGTTGGAAGGCAAGGAGAAAATCTGCGTAGTTGGACTTGGTTATGTGGGCCTTCCTTTGGC
TTTAGCTTTTTCCAAGCACTTCAAAGTGGTTGGTTACGATAAAAAGGTATCAAGAATAGACGAGCTTCTCTCCGGAGTGG
ATACCACAGGTGAGATAAAAAAAGAAGACCTTCTTAAGCACAGTGTAGAGTTTACCAGCGACGAAAGACGCATATCGGAA
GCGAGGTTTATAGTGGTGGCAGTTCCCACACCTGTTGACAAGCTAAAAAATCCAGACCTTTCTTTCCTGAAAGAAGCCTC
TAAAACTGTAGGAAGGCATTTAAGTAAAGGTAGCGTCGTAGTGTATGAGTCCACCGTTTATCCGGGAGCTACCGAGGAAG
TCTGCGTGCCTATACTTGAGAAGGAGAGCGGATTAAAGTGGAAGAGGGACTTCTTTGTAGGGTACTCACCAGAGAGAGTA
AATCCTGGTGATAAGGAGCATACCATAGAAAAAATTGTCAAGGTGGTGGCTGGAGATACAGAGAGCACCCTTGAGCTGAT
AGCATCGGTTTATGGCAAAGTCATAGAGGTGGGTGTTTACAGAGCACCTGATATAAGGACTGCAGAGGCTGCAAAGGTCA
TAGAGAACATACAGAGAGACATAAACATAGCTCTCATGAACGAGCTTTCTGTAATATTTCACAAGTTGGGGATTGATACA
AAGGAAGTTTTAAAAGCTGCAAGCACCAAATGGAACTTTTTGAGGTTTGAGCCAGGACTTGTAGGTGGACACTGTATACC
TGTAGACCCCTACTATCTTGCCCATAAATCCTTAGAGGCTGGACATGTGCCAGAGCTAATTCTGGCGGGAAGAAGGATAA
ATGAGAACATGCCTTACTATGTAGCTTATCAGACAGTAAAACTGCTCATAAAGAGCGGTAAAAGGGTAAATTCTGCAAAA
GTTTTGCTGATGGGCATAACCTTTAAAGAGAATGTACCTGATATCAGAAACAGCAAGGTTTATGAACTTTATAAGGAGCT
AAAAGAGTTCGGCATGGAGGTTTATGTATACGACCCTGTGGCTAACCAGAAGGAGGTAAAGGAAGAGTACGGTATAGACC
TTCTTAAGGACTTAAAAGCGCACGCACCTTATGACTGTATCCTTTTAGCTGTCAAACACAGCATATTTTTAGAGAGTTTT
GACCTTTCCTTTTACAAGGCAATAATGACTGAGCCATACATCCTTGTGGACATAAAAGGCATTTACGAAAAAGATGCAGC
CATTAAAGAGGGTTTTGTTTACTGGAGGCTATAA

Protein sequence :
MIDFKSLLEGKEKICVVGLGYVGLPLALAFSKHFKVVGYDKKVSRIDELLSGVDTTGEIKKEDLLKHSVEFTSDERRISE
ARFIVVAVPTPVDKLKNPDLSFLKEASKTVGRHLSKGSVVVYESTVYPGATEEVCVPILEKESGLKWKRDFFVGYSPERV
NPGDKEHTIEKIVKVVAGDTESTLELIASVYGKVIEVGVYRAPDIRTAEAAKVIENIQRDINIALMNELSVIFHKLGIDT
KEVLKAASTKWNFLRFEPGLVGGHCIPVDPYYLAHKSLEAGHVPELILAGRRINENMPYYVAYQTVKLLIKSGKRVNSAK
VLLMGITFKENVPDIRNSKVYELYKELKEFGMEVYVYDPVANQKEVKEEYGIDLLKDLKAHAPYDCILLAVKHSIFLESF
DLSFYKAIMTEPYILVDIKGIYEKDAAIKEGFVYWRL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
cap1L AAA64651.1 type 1 capsule synthesis gene Virulence SCCcap1 Protein 4e-101 55
tviB NP_458740.1 Vi polysaccharide biosynthesis protein, UDP-glucose/GDP-mannose dehydrogenase Virulence SPI-7 Protein 4e-93 54
tviB NP_807945.1 VI polysaccharide biosynthesis UDP-glucose/GDP-mannose dehydrogenase Virulence SPI-7 Protein 4e-93 54

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
HTH_1295 YP_003432949.1 UDP-glucose/GDP-mannose dehydrogenase VFG0431 Protein 2e-93 54