Gene Information

Name : arsA (BpOF4_02665)
Accession : YP_003425492.1
Strain : Bacillus pseudofirmus OF4
Genome accession: NC_013791
Putative virulence/resistance : Resistance
Product : arsenical pump-driving ATPase
Function : -
COG functional category : P : Inorganic ion transport and metabolism
COG ID : COG0003
EC number : -
Position : 2800165 - 2801940 bp
Length : 1776 bp
Strand : -
Note : COG0003 Oxyanion-translocating ATPase

DNA sequence :
ATGACACAATTTCAATTAACTTCTCATCGCTTTAACCCAGTAAAAGAAGAGCTTACTCCTTATTTATTTTTTACAGGTAA
AGGGGGAGTAGGGAAGACTTCTACAGCTTGTGCGACAGCTGTTGCCTTAGCTGATCAGGGGAAGAAAGTGCTCTTGGTTA
GTACAGATCCTGCCTCTAACCTACAAGATGTCTTTGAACAGGAAATTGGCTATCACGAAACGAAAATCGATGAACTTCCT
AACGTTACAGCGATTAACTTAGATCCCGAGGAAGCAGCAGCTGCTTATCGAAATAAAATGATTGGGCCGTTTCGAGATAA
GCTGCCAGCACCAGTGATTGATCAAATGGAAGAGCAGTTATCGGGTGCATGTACTGTAGAAATTGCCGCATTTGATGAAT
TTGCTACGATCCTGACAAATCCGGAACGAACAAATGAGTATGATCATATTCTTTTTGATACGGCACCGACCGGACATACC
CTTCGTCTCTTACAGCTGCCAACTGCTTGGTCTGGCTTTTTAGATACGAGCACTCATGGAGCTTCATGTCTTGGTCCATT
ATCAGGGTTAGCTGAGAAGAAGGCACTGTATGAACATACAGTTAAAGCCCTGTCAGATGCAGCGAAAACAACACTTATTT
TAGTGGCAAGACCAGAACCGTCTACACTTAAAGAGGCAGCCCGTGCATCAGAAGAGCTGAAGGAGATCGGCCTTGTTAAT
CAATGGCTGCTTATAAACGGGAAAATGCAATCCTATGTAAACGATGATCTGACATCAACTGCGTTTTATAAGCGCCAAGA
ACAAGCCCTGCAATCAATGCCTGCAAAATTACAAGAAACAAAGCAATATGAGCTGCCGTATGTCCCTTATCAGCTGACGG
GAATAGAGTCGCTGCGATCTCTTTTTAATGAGCTGCCTAAGTGCAATGCGCGATTGGTGCCTCGTGCAGACGTTCAGGCT
GATTCTCTTTCTGTCCTGATTAATGACCTTGCGAAAAAAGAGCAAGGAGTTATTTTAACAATGGGAAAAGGTGGAGTCGG
TAAAACGACGGTCGCTGCCGCCGTTGCAGCAGGCCTTGCAAACAAGGGGCTTAAAGTGAAATTAACAACGACAGATCCGG
CTGCGCATGTAAGTGATTTATTCTCTAAAAAAGAGGATCAGCTTATAACGATCAGCCGAATTGACCCGAAAGCCGAAGTA
GAGGCGTATAAACAGGAAGTGTTGTCTGCATCTAGTGAGCATTTAGATGAAGATGGACTTGCCTATTTAGAGGAAGATTT
AAACTCGCCATGTACAGAAGAAATCGCAGTCTTTAGAGCGTTTGCTGATGTAGTTGAAGAAGCCGATGATGCATTTGTCG
TCATTGATACTGCGCCAACCGGCCACACTCTGCTCTTATTAGATGCGGCACATTCCTATCATAAGGAAATGGAACGCAGT
ACGGGGGAAGTGCCTGAATCTGTGAAGAAGTTACTGCCAAGACTGCGAAATCCAAAAGAGACAGATGTGCTTGTCGTCAC
CTTGCCAGAAGCCACGCCGGTATTTGAGGCATCAAGGCTGCAAGATGATCTTATTCGTGCTGATATTACACCAAGCTGGT
GGGTGATTAATCAAAGTTTTGCTGGCACGAATACAATCGACCCAATCTTATCTGAGCGAGCACAAAGTGAGTTCAAATGG
ATCAACGAAGTCATCACCACTCACGCAAAACATACCGTCGTTATTCCTTGGCAGTCTGAAACCATTGAGGGCAGAAAACA
ATTAACCTCATTATAA

Protein sequence :
MTQFQLTSHRFNPVKEELTPYLFFTGKGGVGKTSTACATAVALADQGKKVLLVSTDPASNLQDVFEQEIGYHETKIDELP
NVTAINLDPEEAAAAYRNKMIGPFRDKLPAPVIDQMEEQLSGACTVEIAAFDEFATILTNPERTNEYDHILFDTAPTGHT
LRLLQLPTAWSGFLDTSTHGASCLGPLSGLAEKKALYEHTVKALSDAAKTTLILVARPEPSTLKEAARASEELKEIGLVN
QWLLINGKMQSYVNDDLTSTAFYKRQEQALQSMPAKLQETKQYELPYVPYQLTGIESLRSLFNELPKCNARLVPRADVQA
DSLSVLINDLAKKEQGVILTMGKGGVGKTTVAAAVAAGLANKGLKVKLTTTDPAAHVSDLFSKKEDQLITISRIDPKAEV
EAYKQEVLSASSEHLDEDGLAYLEEDLNSPCTEEIAVFRAFADVVEEADDAFVVIDTAPTGHTLLLLDAAHSYHKEMERS
TGEVPESVKKLLPRLRNPKETDVLVVTLPEATPVFEASRLQDDLIRADITPSWWVINQSFAGTNTIDPILSERAQSEFKW
INEVITTHAKHTVVIPWQSETIEGRKQLTSL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
arsA2 YP_001007632.1 arsenical pump-driving ATPase Not tested YAPI Protein 2e-110 48
SH0111 YP_252026.1 arsenical pump-driving ATPase Not tested SCCmec Protein 5e-91 42

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
arsA YP_003425492.1 arsenical pump-driving ATPase BAC0572 Protein 6e-111 50
arsA YP_003425492.1 arsenical pump-driving ATPase BAC0571 Protein 2e-113 50
arsA YP_003425492.1 arsenical pump-driving ATPase BAC0030 Protein 4e-109 50