Gene Information

Name : UCYN_11750 (UCYN_11750)
Accession : YP_003422225.1
Strain : Cyanobacterium sp. UCYN-A
Genome accession: NC_013771
Putative virulence/resistance : Virulence
Product : pyruvate kinase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0469
EC number : 2.7.1.40
Position : 1326145 - 1327896 bp
Length : 1752 bp
Strand : -
Note : PFAM: PEP-utilising enzyme, mobile domain; Pyruvate kinase, alpha/beta domain; Pyruvate kinase, barrel domain; TIGRFAM: pyruvate kinase

DNA sequence :
ATGCCTCGTCGAACTAAGATAGTGGCAACTATTGGTCCTGCTACTCAAGACAAAGAAATTCTACGCAAATTAATTTTGGC
TGGCGCAACTACCTTTCGTCTTAATTTTTCCCATGGTGATCATGAATGTCATGCACAAAGTATTAAGCTTATCCGACAAA
TTGCTTTTGAATTACATCAACCTGTAGCTATTCTTCAAGATTTACAAGGACCTAAAATTCGTCTTGGATTATTTAAAAAC
AATTCCATAACTCTCGAAGCTGGTGATTCTTTTATTCTTACAAGCAGAGAAGTAGAATGTAATAAAGAAATTAGTTACGT
TACATATAAAAATTTAATAAAAGAGGTTCCAGAACAGGCAAGAATTTTAATGGATGATGGCAAAGTCGAAATGCTAGTTG
AGAAAGTTGATATTGATAATCAAAATTTATATTGCAGAGTAGTTATTGGCGGGATTTTGTCTAATAATAAAGGTGTTAAT
TTTCCGGGAATTTCCTTATCCGTAAAAGCGTTAACAACTAAAGATAAAAAAGATCTGATCTTTGGTTTGGAAAATCAAGT
AGATTGGGTCGCATTAAGTTTTGTAAGAAGTTCGCAAGATATTTTAGAAGTGAAAGAAATTATAACTAATGCAGGAAAAA
ATATTCCGATAATTGCAAAAATTGAAAAACACGAAGCTATTGACAATATGGAACAAATTCTCAATTTATGTGATGGTGTA
ATGGTTGCCAGAGGGGACTTAGGCGTTGAGTTACCACCAGAAGATGTTCCTATTTTACAAAAACGCTTAATTGCCACTGC
AAACAATTTAGGAATCCCCGTAATTACTGCTACTCAGATGTTAGATAGCATGGTTAATAATCCTCGTCCTACTCGTGCAG
AAGTGTCTGATGTAGCCAATGCAATTTTAGATGGTACTGATGCAGTCATGTTATCAAATGAAACAGCTGTAGGAAAATAT
CCTGTTCAGGCTGTCAAAACTATGGCGACTATTGCCGAACGTATAGAAAAAGAGCCTACAACCATAAAAATTTCCTCTCA
GAGAAAACAATCTATTACTAATGCAATTTCGGCAGCAGTTAGTCAAATTGCCGAACAATTAAACGCAGCTGCAATAATGT
CTTTAACAAAAACAGGCTTAACTGCTCGTAATATTTCTAAATTTCGTCCTCATATTCCAATATTGGCTGTAACTCCTCGA
ATAGATGTTGCAAGACAATTACAATTAGTTTGGGGGTTGGAAACTTTATTAGTTTTAGATTCACCATCAGCTACTCAGAC
TTTCCAATCAGCAATTAATGTAGCTCAAGAAAATAATTTACTTAAAGACGGAGATTTGGTCGTCATGACAGCTGGAAGTA
TTCAAGGGATAACGGGATCAACCGACTTAATAAAGATAGAGACGATTAGAGCAATACTAGGTAAAGGTATAGGTGTTGGG
CAGGGTTTAGCAAGTGGTAGAGCAAGAATTGCTAGTTATGCTAAAGATTTAAATAACTTTGAATCAGGAGATATTTTAGT
AGTACCTGAAACAAATGCACAATTTGTAGAAATCATGAGAAAAGCATCAGGAGTTATTACAGAGGAATCAAGCCTAGACA
GCCATGCTGCAGTAATTGGAACTCGTTTAGGTGTACCAGTTATTCTTGGCTTTAAAGATGCAACTAAAAATATTTCCGAA
GGTATAATCATCACCATAGATACTGAAAAAGGACAAGTCTATTCTGGTATTACTAAGGATAAATATTGTTAG

Protein sequence :
MPRRTKIVATIGPATQDKEILRKLILAGATTFRLNFSHGDHECHAQSIKLIRQIAFELHQPVAILQDLQGPKIRLGLFKN
NSITLEAGDSFILTSREVECNKEISYVTYKNLIKEVPEQARILMDDGKVEMLVEKVDIDNQNLYCRVVIGGILSNNKGVN
FPGISLSVKALTTKDKKDLIFGLENQVDWVALSFVRSSQDILEVKEIITNAGKNIPIIAKIEKHEAIDNMEQILNLCDGV
MVARGDLGVELPPEDVPILQKRLIATANNLGIPVITATQMLDSMVNNPRPTRAEVSDVANAILDGTDAVMLSNETAVGKY
PVQAVKTMATIAERIEKEPTTIKISSQRKQSITNAISAAVSQIAEQLNAAAIMSLTKTGLTARNISKFRPHIPILAVTPR
IDVARQLQLVWGLETLLVLDSPSATQTFQSAINVAQENNLLKDGDLVVMTAGSIQGITGSTDLIKIETIRAILGKGIGVG
QGLASGRARIASYAKDLNNFESGDILVVPETNAQFVEIMRKASGVITEESSLDSHAAVIGTRLGVPVILGFKDATKNISE
GIIITIDTEKGQVYSGITKDKYC

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
pykF NP_805051.1 pyruvate kinase Not tested SPI-2 Protein 3e-81 45
pykF CAA68205.1 pyruvate kinase like protein Not tested SPI-2 Protein 1e-80 45
STY1744 NP_456147.1 pyruvate kinase Not tested SPI-2 Protein 3e-81 45
pykF YP_216386.1 pyruvate kinase Not tested SPI-2 Protein 3e-81 45

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
UCYN_11750 YP_003422225.1 pyruvate kinase VFG0479 Protein 1e-81 45