Gene Information

Name : Gobs_4210 (Gobs_4210)
Accession : YP_003411143.1
Strain : Geodermatophilus obscurus DSM 43160
Genome accession: NC_013757
Putative virulence/resistance : Resistance
Product : cystathionine gamma-synthase
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0626
EC number : 2.5.1.48
Position : 4420674 - 4421825 bp
Length : 1152 bp
Strand : +
Note : PFAM: Cys/Met metabolism pyridoxal-phosphate- dependent protein; aromatic amino acid beta-eliminating lyase/threonine aldolase; KEGG: sgr:SGR_2579 cystathionine gamma-synthase

DNA sequence :
ATGAGCCCCACGCACGGCTTCAACACCCGCGCCATCCACGCCGGGCAGGACCCGGACCCGGCCACCGGCGACGTCGTCGT
CCCCCTGCACCTGGCGACCACCTTCAAGCAGGACGGCGTCGGCGGGCTGCGCGGCGGCTACGAGTACGCGCGCAGCGCCA
ACCCCACGCGGACGGCGCTGCAGGAGGCGCTGGCCGCCCTCGAGCAGGGCCGCACCGCGCTGGCGTTCGCCTCCGGCCTG
GCCGCCGAGGACACGCTGCTGCGGACGGTCTGCGAGCCGGGCAGCCACGTCGTCCTCGGGGGCGACGCCTACGGCGGGAC
GTTCCGGCTCATCTCCAAGGTGGCCTCCCGCTGGGGCGTCGAGCACACGCCGGCCGACCTCAACGACCCCGACGCGCTGC
GGGCGGCGATCCGGCCGAGCACGCGGGTCATCTGGTGCGAGACGCCGACCAACCCGCTGCTCAACATCGCCGACATCGCG
CTGACCGCCGAGGTCGCCCACGACGCCGGTGCGCTGCTCGTTGTCGACAACACCTTCGCCTCGCCCTACCTGCAGCAGCC
GCTGACCCTCGGCGCCGACGTCGTCGTCCACTCGACGACGAAGTACCTCGGTGGGCACTCCGACGTCGTCGGCGGCGCGC
TGGTCGTCGGGGACGACGCCGAGCTCGCCGAGCAGCTGGCCTTCTCGCAGAACGCGATGGGTGCCGTCTCCGGCCCGCTG
GCCGACTGGCTGGTGCTGCGCGGCATCAAGACCCTCGGCGTCCGGATGGACCGGCACCAGGACAACGCCGCCCGGGTGGT
GGAGTTCCTGCTCGGCCACCCGGCCGTCGCCTCGGTGCGCTACCCGGGCCTGCCCGACCACCCCGGGCACGAGATCGCCG
CGAAGCAGATGTCCGGGTTCGGCGGGATGCTCTCGTTCCGCCTGGCAGCCGGGGAGGACGCCGCGCTGCGGGTGTGCGAG
CGGGCGCAGGTCTTCACCCTCGCGGAGTCCCTGGGCGGGGTGGAGTCGCTGATCGAGCACCCGGCGCGGATGACCCACGC
CAGCGCCGCCGGCTCCCCGCTGGAGGTGCCGGCCGACCTGGTCCGGCTCTCGGTCGGCATCGAGGACGCCGAGGACCTGA
TCGCCGACCTCGACCAGGCCCTGGCACTGTGA

Protein sequence :
MSPTHGFNTRAIHAGQDPDPATGDVVVPLHLATTFKQDGVGGLRGGYEYARSANPTRTALQEALAALEQGRTALAFASGL
AAEDTLLRTVCEPGSHVVLGGDAYGGTFRLISKVASRWGVEHTPADLNDPDALRAAIRPSTRVIWCETPTNPLLNIADIA
LTAEVAHDAGALLVVDNTFASPYLQQPLTLGADVVVHSTTKYLGGHSDVVGGALVVGDDAELAEQLAFSQNAMGAVSGPL
ADWLVLRGIKTLGVRMDRHQDNAARVVEFLLGHPAVASVRYPGLPDHPGHEIAAKQMSGFGGMLSFRLAAGEDAALRVCE
RAQVFTLAESLGGVESLIEHPARMTHASAAGSPLEVPADLVRLSVGIEDAEDLIADLDQALAL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAR0460 YP_039909.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 6e-65 44
SAS0418 YP_042545.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 6e-66 44
metB YP_281510.1 cystathionine beta-lyase Not tested Not named Protein 5e-47 41

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Gobs_4210 YP_003411143.1 cystathionine gamma-synthase BAC0207 Protein 9e-52 44