Gene Information

Name : Gobs_0191 (Gobs_0191)
Accession : YP_003407368.1
Strain : Geodermatophilus obscurus DSM 43160
Genome accession: NC_013757
Putative virulence/resistance : Virulence
Product : urease subunit alpha
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0804
EC number : 3.5.1.5
Position : 204565 - 206286 bp
Length : 1722 bp
Strand : +
Note : KEGG: rha:RHA1_ro05680 urease subunit alpha; TIGRFAM: urease, alpha subunit; PFAM: amidohydrolase; Urease alpha-subunit domain protein

DNA sequence :
ATGGTGCTGCTGTCCCGCGAGCGCTACGCGCAGCTCTACGGCCCGACGGTCGGCGACCGCGTCCGGCTGGCCGACACCGA
CCTGCTCATCGAGGTGGAGGAGGACCGCTGCGGCGGCCCCGGCCGGGCCGGCGAGGAGGCGGTCTTCGGCGGCGGCAAGG
TGATCCGCGAGTCGATGGGGCAGGGCCGGGCCACCCGCGCCGAGGGCGCGCCCGACCTGGTGATCACCGGTGCGGTCGTC
CTCGACCACTGGGGGGTCGTCAAGGCCGACGTCGGCATCCGGGACGGCCGGATCGTGGCGCTCGGCAAGGCGGGCAACCC
CGACACGATGGACGGCGTCCACCCCGGCCTGGTCATCGGCCCGGGCACCGAGGTGCTCGCCGGGAACGGCCGCATCCTCA
CCGCCGGCGGCATCGACTGCCACGTGCACTTCATCTGCCCGCAGATCGTCCCCACGGCGCTGGGCTCGGGCGTCACCACG
CTGATCGGCGGCGGCACCGGTCCGGCGGAGGGGTCCAAGGCCACCACGATCACCCCGGGCGACTGGTACCTGGCCCGCAT
GCTCGAGGCGATGGACCCGTGGCCGGTCAACGTCGCGCTGCTGGGCAAGGGCAACACCGTCTCGCAGGAGTCGATGGAGG
AGCAGCTCCGTGGCGGCGCCAGCGGGTTCAAGCTGCACGAGGACTGGGGGTCCACGCCGGCCGCCATCGACGCCTGCCTC
ACCGTGGCCGGGCGCAACGGCGTCCCGGTGGCCCTGCACTCGGACACGCTCAACGAGGCCGGCTTCATCGAGGACACCCT
GGCCGCCATCGCCGGCCGGAGCATCCACGCGTACCACACCGAGGGGGCCGGGGGTGGTCACGCGCCGGACATCATCACCG
TCGCCGGGCACCCGAACGTGCTACCGAGCAGCACCAACCCGACGCGGCCGCACACGGTCAACACCCTCGACGAGCACCTC
GACATGCTCATGGTCTGCCACCACCTCGACTCGTCGGTGCCCGAGGACCTGGCCTTCGCCGAGAGCCGGATCCGGCCGAC
GACGATCGCCGCCGAGGACCTGTTGCACGACGTCGGGGCCATCTCGATGATCGGCTCCGACGCGCAGGCGATGGGCCGGG
TCGGTGAGGTCGTGCTGCGGACCTGGCAGACCGCGCACGTGATGAAGCGCAAACGGGGGTCGCTGGCCGGGGACGGTGCG
GCGGACAACCTGCGGGCCCGCCGGTACGTCGCCAAGTACACGATCTGCCCGGCCGTGGCGCACGGGATCGACGGCGAGGT
CGGCTCGGTGGAGCCGGGCAAGCTGGCCGACCTGGTGCTGTGGGACCCGCGGTTCTTCGGCGTCCGCCCGCACGCCGTGC
TCAAGGGCGGGGTGATCGCCTGGGCGCAGATGGGTGACGCCAACGCCTCCATCCCCACCCCGCAGCCGCAGCTGCCCCGG
CCGATGTTCGGCGCGTACGGGCGGGTGCCGGCCCGGACGGCGCTGCACTTCGTCGCCCCCGCGGCGGTCGAGGCGGGGCT
GGCCGACCGGCTCGGCGTCGACCGCCGGCTGGTCGCGGTCACCGACACCACCCGGCTCGCCAAGGCTGACATGCCGGAGA
ACACCGCGCTGCCCGACATCCGGGTCGACCCCGACACCTTCACCGTGCGGGTGGACGGCGAGGTGTGGGAGCCCGAGCCG
GTGCGCGAGCTGCCGATGGCCCAGCGCTACTTCCTCTTCTGA

Protein sequence :
MVLLSRERYAQLYGPTVGDRVRLADTDLLIEVEEDRCGGPGRAGEEAVFGGGKVIRESMGQGRATRAEGAPDLVITGAVV
LDHWGVVKADVGIRDGRIVALGKAGNPDTMDGVHPGLVIGPGTEVLAGNGRILTAGGIDCHVHFICPQIVPTALGSGVTT
LIGGGTGPAEGSKATTITPGDWYLARMLEAMDPWPVNVALLGKGNTVSQESMEEQLRGGASGFKLHEDWGSTPAAIDACL
TVAGRNGVPVALHSDTLNEAGFIEDTLAAIAGRSIHAYHTEGAGGGHAPDIITVAGHPNVLPSSTNPTRPHTVNTLDEHL
DMLMVCHHLDSSVPEDLAFAESRIRPTTIAAEDLLHDVGAISMIGSDAQAMGRVGEVVLRTWQTAHVMKRKRGSLAGDGA
ADNLRARRYVAKYTICPAVAHGIDGEVGSVEPGKLADLVLWDPRFFGVRPHAVLKGGVIAWAQMGDANASIPTPQPQLPR
PMFGAYGRVPARTALHFVAPAAVEAGLADRLGVDRRLVAVTDTTRLAKADMPENTALPDIRVDPDTFTVRVDGEVWEPEP
VRELPMAQRYFLF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ureC NP_286680.1 urease subunit alpha Virulence TAI Protein 2e-163 61
ureC NP_287088.1 urease subunit alpha Not tested TAI Protein 2e-163 61
ureC YP_005684266.1 Urease alpha subunit Not tested PiCp 7 Protein 4e-157 57
ureC YP_005682174.1 Urease alpha subunit Not tested PiCp 7 Protein 4e-157 57
ureC YP_003784325.1 urease subunit alpha Not tested PiCp 7 Protein 4e-157 57
ureC YP_005686358.1 Urease alpha subunit Not tested PiCp 7 Protein 4e-157 57

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Gobs_0191 YP_003407368.1 urease subunit alpha VFG0270 Protein 2e-146 56